Soroconverses

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Seroconversion of a Measles Disease
TPM-Microbiology
Infection Symptoms Early Diagnostic
IgG
IgM
Exanthema
Rel.
Conc.
ELISA
Days Days
Acute
Phase
Incubation
10 Days
Virus
Excretion
Weeks
–10 –8 –3 0 2 4 6 8 101214 3 4 5 6 7 8 3 4 5 6 1 2 10
Month Years
Seroconversion of a
Mononucleosis (EBV) Disease
Weeks Month YearsDaysDays
–14 –4 0 2 4 6 8 10 1214 3 4 5 6 7 8 3 4 5 6 1 2 10
IgG
IgM
Infection Early DiagnosticSymptoms
Incubation
4–14 Days Acute Phase
Rel.
Conc.
ELISA
TPM-Microbiology
Seroconversion of a Mumps Disease
Weeks Month YearsDaysDays
–35 –11 –6 0 42 6 8101214 3 4 5 6 7 8 3 4 5 6 1 2 10
IgG
IgM
Infection Early DiagnosticSymptoms
Incubation
11–35 Days Acute Phase
Virus in Saliva
Rel.
Conc.
ELISA
TPM-Microbiology
Seroconversion of a Rubella Disease
TPM-Microbiology
SymptomsContact Early Diagnostic
IgG
2048
1024
512
256
128
64
32
10321211121086420–7–14
Days Days Month Years
14
16
8
IgM
HIT
HIT
1:
Rel.
Conc.
ELISA
Incubation
14-21 Days
Virus in Pharynx
Virus
in Blood
Exanthema
Seroconversion of a Toxoplasmosis Disease
Weeks Month Years
10,5 32 4 2 3 4 5 6 7 10 11 128 9 2 3 10
Infection Early Diagnostic
IgG
IgM
Rel. 
Conc.
IgG
IU/ML
3200
1600
800
400
200
100
Incub.
TPM-Microbiology
Seroconversion of a Varizella-/Zoster Virus Disease
TPM-Microbiology
SymptomsInfection
IgG
3 4 5 6 7 8 3 4 5 6 7 8 1 28 10 12 146420–10 –5 –1–20
Days WeeksDays Month Years
CFT
1:
320
160
80
40
20
10
IgM
CFT
Rel.
Conc.
ELISA
Acute Phase
Virus
Excretion
Incubation
10-20 Days
Early Diagnostic
Seroconversion of a Cytomegalovirus Disease
WeeksDays Month Years
–40 0 2 31 4 5 6 72 3 4 10 11 128 9 2 3
10
20
40
80
160
320
CFT
1:
Infection Symptoms Early Diagnostic
IgG
CFT
IgM
Incubation
30–40 Days
Rel. 
Conc.
ELISA
TPM-Microbiology
Seroconversion of a 
Tick-Born-Encephalitis
WeeksDays Month Years
–10
36
37
38
39
40
°C
0 1 2 3 4 6 8 102 432
Infection Symptoms Early Diagnostic
IgG
Temperature Curve
IgM
Without
SymptomsStage I
Stage II
CNS-Symptoms
Incub.
7–14 Days
Rel. 
Conc.
ELISA
TPM-Microbiology
Seroconversion of a Candida Albicans Disease
Weeks Month YearsDays Days
–2 20 4 6 12108 18 20 221614 4 5 6 2 4 6 1 2 3 4 5
HT
IF
Infection Early DiagnosticHT
Incubation
1280
640
320
160
80
40
20
10
IF
IU/ML
6400
3200
1600
800
400
200
TPM-Microbiology
Seroconversion of a
Syphilis Disease (Untreated)
Infection Early DiagnosticRel.
Conc.
Incub. Primary SecondaryExanthema
Tertiary
Neuro Syphilis
Weeks
0 2 31 4 5 76 8 9 10 11 12 2 3 4 5 10 20 30 40 50
Years
IgG
EIA/Ig, 
TPHA
VDRL
IgM
Spontaneous
 Healing
TPM-Microbiology
Late Phase of a HIV 1 Disease
Years
HIV 1 Antigen
Anti-HIV-1 Envelope Protein
Anti-HIV 1 Core 
 Protein
Rel. 
Conc.
TPM-Microbiology
Early Diagnostic of a HIV 1 Disease
Years6–8 Weeks
Infection
HIV 1 Antigen
Anti-HIV 1/2 Total
Rel. 
Conc.
TPM-Microbiology
Seroconversion 
of a HIV 1 Disease
Years6–8 Weeks
Infection
Anti-HIV 1 Core
 Protein
Anti-HIV 1 Envelope
 Protein
HIV 1 Antigen
HIV 1 Antigen
Rel. 
Conc.
ELISA
TPM-Microbiology
Seroconversion of a 
Herpes Simplex Primary Disease
TPM-Microbiology
SymptomsInfection
IgG
4 6 8 3 4 5 6 2 38 10 12 14 16 18 206420– 6– 4 – 2– 8
Days WeeksDays Month Years
640
CFT
1:
320
160
80
40
20
10
IgM
CFT
Rel.
Conc.
ELISA
Vesical LesionIncubation3-9 Days
Early Diagnostic
Seroconversion of a
Lyme Disease (Untreated)
TPM-Microbiology
SymptomsInfection
IgG
23 4 5 6 7 8 9 10 11 12 3 486420–30
Days Weeks Month Years
IgM
AB Total
Rel.
Conc.
ELISA
Inkubation
14-21 Tage
Neurologic Symptoms
Arthritis
ACA
ECM
Incub.
2-30 Days
Seroconversion of a
Hepatitis A-Virus Disease
Rel.
Conc.
Icterus and other
Symptoms
Transaminases
Virus in Faeces and Liver
Weeks
1 2 3 4 5 6 7 8 9 10 11 12
IgG
Anti-HAV
(IgM/IgG)
IgM
TPM-Microbiology
Seroconversion of a
Hepatitis B-Virus Disease
Weeks Years
4–12 2–12 2–16
Symptoms
Anti-HBc
Anti-HBs
Anti-HBe
Anti-HBc IgM
HBsAg
HBe
Ag
Post Acute
Stage
Acute
Stage Post Disease StageIncub.
Rel. 
Conc.
TPM-Microbiology