LIVRO Velio Bocci Ozone-A New Medical Drug
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LIVRO Velio Bocci Ozone-A New Medical Drug


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OZONE
A New Medical Drug
by
Velio Bocci
OZONE
 A New Medical Drug
Emeritus Professor of Physiology at the University of Siena,
Siena, Italy
Medical Doctor, Specialist in Respiratory Diseases and Haematology and
A C.I.P. Catalogue record for this book is available from the Library of Congress.
Published by Springer,
P.O. Box 17, 3300 AA Dordrecht, The Netherlands.
Sold and distributed in North, Central and South America
by Springer,
101 Philip Drive, Norwell, MA 02061, U.S.A.
In all other countries, sold and distributed
by Springer,
P.O. Box 322, 3300 AH Dordrecht, The Netherlands.
Printed on acid-free paper
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All Rights Reserved
No part of this work may be reproduced, stored in a retrieval system, or transmitted
in any form or by any means, electronic, mechanical, photocopying, microfilming, recording
or otherwise, without written permission from the Publisher, with the exception
of any material supplied specifically for the purpose of being entered
and executed on a computer system, for exclusive use by the purchaser of the work.
Printed in the Netherlands.
ISBN 1-4020-3139-4 (HB)
ISBN 1-4020-3140-8 (e-book)
© 2005 Springer
This book is dedicated to all patients with the wish to regain their
health with or without oxygen-ozonetherapy
vii
PREFACE
Is there any reason to write a third book on the topic of oxygen-ozone
therapy? The first was written four years ago for italian physicians, who, for 
some time, had complained about the lack of precise ozone informations. 
Then it became unavoidable to write a book for english-speaking people and 
it took a couple of years because i considered worth it while to examine the
problem in details with attention to basic findings, so that it could also be
useful to scientists and clinicians. The book was briefly reviewed in the new
york academy of sciences magazine ( 1-2, 2003, 14) and was awarded the
\u201cTramezzi\u201d prize in Rome, October 2003. However the book had not been as
successful as i had hoped because, particularly american scientists remained
sceptical and disinterested. However a letter from prof. L.Packer was
encouraging saying: \u201cthere is growing evidence that oxidants like many ros
including ozone provide a mild oxidant stress which under certain
circumstances actually induce the formation of phase 1 and phase 2
enzymes, strengthening the antioxidant defence system through an
adaptation process. Thus it would be rational that a mild treatment with
ozone stimulates the antioxidant defence system. So i think some of your 
ideas have a foundation in current scientific work.\u201d Indeed i have several 
reasons to believe that one of the most important pedestals of ozonetherapy 
is based on the induction of oxidative stress proteins.
In Chapter 34 of my previous book (2002), I emphasized the usefulness
of biooxidative therapies in poor-countries, where a billion people have no
other medical resources but world health authorities, particularly WHO had
remained disinterested in this approach. It is depressing to realize how useful
proposals remain unheard of and how much time and work are requested 
before their implementation.
However, the worst disappointment has been on reading a few letters of 
distinguished American scientists in the field of free-radicals, who were and
remained biased towards ozonetherapy. Actually several scientists, who
surely received the book did not even bother to answer. Someone, who, by
reading his papers, I judged to be very clever, politely wrote me that,
although the book presented some interesting aspects, it could not convince
him because the ruling dogma in the USA is that \u201cozone is toxic and should 
not be used in medicine\u201d. Although several others were not so naïve to say
such a thing, it was clear that the book had failed to remove the prejudice
from their heads.
viii
On the other hand, I received a few positive responses from clinicians,
who appreciated my effort in creating a rational scheme able to clarify how
ozone acts and why toxicity could be avoided. Several practitioners
confessed to be disinterested in the biochemical aspects because they hardly
had the time to read the practical part.
On the whole these remarks taught me that much more work was needed
before reversing the antagonism, for correcting the problem of charlatans
and objectively establish the pros and cons of ozonetherapy. During the last 
three years, personal experience has convinced me that a judicious use of 
ozone can be very useful in some diseases when orthodox medicine has no 
further resources and patients are abandoned to their fate. For them ozone is
more valuable than gold because, at least for some, it can restore hope and 
health. I feel I am a lucky man because towards the end of my academic life,
in 1988, by mere accident, I stumbled on the ozone problem that although
quite controversial, is a real trove. I believe so because ozone, like oxygen,
is such a basic molecule able to activate a great number of vital processes. It
depresses me to think that ozone, the cheapest drug on earth, is today either 
badly or minimally used because orthodox medicine refuses to evaluate it 
and Health Authorities are antagonistic or negligent. Both are responsible for 
leaving millions of people suffering and dying. I must not get discouraged 
and continue to work and hope that ozonetherapy will eventually benefit 
many people. I cannot hide my dream of organizing and gratuitously
working in a large clinic with enthusiastic collaborators able to evaluate the
full relevance of ozonetherapy. There are many philanthropists helping the
development of arts, science and sport and one day we may be lucky to find 
someone who believes and values this approach.
In conclusion what are the aims of this book?
This has been specifically written for physicians, who want to learn and
then perform a correct ozonetherapy. Moreover, by using a plain scientific
language, the book should be useful for the layman, who must receive the
most objective information avoiding any undue hype. In comparison with
the former book, I will strive to be clear without omitting the basic concepts 
that are essential to understand how ozone works without causing deleterious 
effects. I will refrain from adding chemical formulae and complex diagrams 
because I have been told that they are somewhat irritating or useless for 
inexpert people. I would be enthusiastic to help and collaborate with clinical
researchers if they are genuinely interested in evaluating the validity of 
ozone-therapy.
The greatest effort will be dedicated to clarify in which diseases
ozonetherapy has been proved to be really useful and in others where the
efficacy remains uncertain. Because mass media and popular books often
tend to elicit unrealistic hopes, it appears necessary that the reader is
precisely informed on the best available options provided by orthodox
ix
medicine and, if necessary, by ozonetherapy that, in any case, remains a 
complementary approach or the last resort. For the sake of brevity and
minimal competence, I will not suggest other important complementary
approaches unless scientific data have proven their value.
Velio Bocci
xi
ACKNOWLEDGEMENTS
It has taken some time to have this book ready because I wanted to fully
update results of both orthodox and ozone therapies. I would like to thank
many collaborators who, throughout the years, have helped me in studying
the biological and therapeutic effects of ozone.
Although I tried to do my best in writing the book, I apologise for the 
poor style and probably some mistakes although the manuscript has
undergone the linguistic revision. I am very grateful