What is the main cause of acute myocardial infarction?

The main cause of acute myocardial infarction is the rupture or erosion of an atheromatous plaque.
The risk of plaque rupture depends on its composition, vulnerability, and degree of stenosis.
Around 75% of thrombi related to myocardial infarction develop in plaques that cause mild or moderate stenosis.
The necrosis of subepicardial myocytes needs 4 to 6 hours to complete.
a) Statements 1 and 2 are correct.
b) Statements 2 and 3 are correct.
c) Statements 1 and 4 are correct.
d) Statements 2 and 4 are correct.