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<p>5' 3' T UV radiation produces AA a thymine dimer. 3' 5' 5' 3' Once the dimer has been detected, the surrounding DNA is opened to form a bubble. AA 3' 5' T 5' 3' Enzymes cut the damaged region out of the bubble. A A 3' 5' new, undamaged DNA 5' 3' TT A DNA polymerase replaces the excised (cut-out) DNA, and a ligase seals the backbone. 3' 5'</p>

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