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Solutions for Carbohydrates and Nucleic Acids
HO
OH
H
N
NO O
O
CH3
HO
N
H
N
NO O
O
CH3
N
N
N
H
N
NO O
O
CH3
N
N
OP
O
O
O
P
O
O
O
P
O
O
O
2'-deoxythymidine
(abbreviated dT)
72 Bonds from C to H are omitted for simplicity.
2'3'4'
5'
2'3'4'
5' 3'-azido-2',3'-dideoxythymidine
(AZT)
No phosphate can attach to the azide group, so
synthesis of the DNA chain is terminated.
2'3'4'
5'
AZT 5'-triphosphate
(a)
(b)
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