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What are the symptoms of acromegaly? Prognathism, prominent nose, succulent hand (increase in soft tissues) -> acromegalic facies (increase in GH).

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Hipertensao Arterial Secundária
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Nefrologia Universidade Metropolitana de SantosUniversidade Metropolitana de Santos

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Acromegaly is a hormonal disorder that occurs when the pituitary gland produces excessive growth hormone (GH) after the growth plates have closed. The symptoms of acromegaly can vary, but some common signs include: 1. Enlarged hands and feet: This is often one of the first noticeable symptoms. The hands and feet may become larger and wider, and the fingers and toes may appear thicker. 2. Facial changes: Acromegaly can cause changes in facial features, such as a protruding jaw (prognathism), enlarged nose, thickened lips, and an enlarged tongue. These changes are collectively known as acromegalic facies. 3. Soft tissue swelling: The soft tissues in various parts of the body, including the hands, feet, and face, may become swollen and thickened. 4. Joint pain: Acromegaly can lead to joint pain and stiffness, particularly in the hands and wrists. 5. Enlarged organs: Over time, the excessive GH can cause the organs to enlarge, including the heart, liver, and kidneys. 6. Sleep apnea: Acromegaly can increase the risk of sleep apnea, a condition characterized by pauses in breathing during sleep. It's important to note that these symptoms can develop gradually over time, and the severity can vary from person to person. If you suspect you may have acromegaly, it's best to consult with a healthcare professional for a proper diagnosis and treatment.

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