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Farmacocinética
É a passagem do fármaco
aos tecidos.
A distribuição dele é maior em
orgãos ricos em vasos sanguíneos,
Após ser absorvido ou administrado
diretamente na corrente sanguínea,
o fármaco se distribui por todos os
sistemas incluído o líquido intersticial,
líquido intracelular, tecido muscular,
tecido ósseo, SNC, tecido adiposo além
de unhas e pêlos
Distribuição
Nesta fase
ocorre a
liberação do
fármaco na forma
farmacêutica.
Biofarmacêutica
É a passagem do
fármaco ao sangue,
os medicamentos
lipofilicos são mais
absorvidos porque as
membranas plasmáticas
das células contém
uma camada de lipideos.
Absorção
EXCREÇÃO
DISTRIBUIÇÃO
METABOLISMO
ABSORÇÃO
Farmacocinética
A remoção de um fármaco
do organismo humano pode
ocorrer através de varias vias:
renal, biliar, intestinal,
pulmonar,além do suor,
saliva, secreção
nasal, e, leite em mães que
amamentam. A principal
via de excreçãode
fármacos é constituída pelo
sistema renal.
Excreção
processo de alteração na
estrutura química
que os fármacos sofrem no
organismo,geralmente por
conversão enzimática,
com a finalidade dediminuir
sua lipossolubilidade e
facilitar sua excreção.
Metabolismo
8287.jpg
Camada 1
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"secondaryColor": "RGB255,USER,255,255,255,100,00000000-0000-0000-0000-000000000000",
"winding": "1"
},
"InnerMarkerFill": {
"type": "1",
"primaryColor": "RGB255,USER,0,0,0,100,00000000-0000-0000-0000-000000000000",
"secondaryColor": "RGB255,USER,255,255,255,100,00000000-0000-0000-0000-000000000000",
"winding": "1"
}
}
}
},
"symmetry": {
"~symmetry~": {
"type": "0",
"outline": {
"width": "762",
"color": "RGB255,USER,0,160,255,100,00000000-0000-0000-0000-000000000000"
},
"numLines": "1",
"joinThreshold": "20000",
"originX": "0",
"originY": "0",
"rotation": "90000000"
}
},
"color styles": {
"palette_xml": {
"tag": "palette",
"attributes": {
"guid": "488dcf65-47d2-42e9-84fb-9f29c54afa28",
"name": "Paleta de estilos de cores"
}
},
"ruled-harmonies": [
]
},
"fom data": {
}
}
META-INF/metadata.xml
2021-03-05T14:10:32-03:00
2021-03-05T15:07:16-03:00
2021-03-05T15:07:16-03:00
application/x-vnd.corel.zcf.draw.document+zip
Cliente
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201c6c25-6765-4cb6-909a-bd974976f60c
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0
Anamortee
Arial
Baby Lovely
Batang
Kaufmann BT
MS Gothic
Monotype Corsiva
Cliente
CorelDRAW 2020
1046
false
2200
2
0
2200
412
0
true
1046
a1454cda-45ab-4c53-8efc-4f4513e70b37
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30800000
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3080 x 3080 mm
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1046
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Paleta RGB padrão
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CMYK
RGB
Paleta RGB padrão
META-INF/links.xml
META-INF/container.xml
content/data/Bitmaps.dat
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