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TRABAJOS PUBLICADOS POR GRUPOS DE INVESTIGACIÓN 
DEPARTAMENTO DE QUÍMICA BIOLÓGICA
2006-2009
Laboratorio de Biología Molecular: Transducción de señales (Silvia Moreno/ Silvia 
Rossi)
1. Gironella M, Malicet C, Cano C, Sandi MJ, Hamidi T, Tauil RM, Baston M, Valaco P, 
Moreno S, Lopez F, Neira JL, Dagorn JC, Iovanna JL. p8/nupr1 regulates DNA-repair 
activity after double-strand gamma irradiation-induced DNA damage.J Cell Physiol. 2009 
Dec;221(3):594-602.
2. Ocampo J, Fernandez Nuñez L, Silva F, Pereyra E, Moreno S, Garre V, Rossi S. A 
subunit of protein kinase A regulates growth and differentiation in the fungus Mucor 
circinelloides. Eukaryot Cell. 2009 Jul;8(7):933-44.
3. Rinaldi J, Ocampo J, Rossi S, Moreno S. A novel activating effect of the regulatory 
subunit of protein kinase A on catalytic subunit activity. Arch Biochem Biophys. 2008 Dec 
15;480(2):95-103.
4. Ocampo J, Moreno S, Rossi S.PKA from Mucor circinelloides: model to study the role 
of linker I in the interaction between R and C subunits. Biochem Biophys Res Commun. 
2007 Oct 26;362(3):721-6. Epub 2007 Aug 20.PMID: 17761146
5. Argimón S, Galello F, Pereyra E, Rossi S, Moreno S. Mucor rouxii Rho1 protein; 
characterization and possible role in polarized growth. Antonie Van Leeuwenhoek. 2007 
Apr;91(3):237-51.
6. Pereyra E, Ingerfeld M, Anderson N, Jackson SL, Moreno S. Mucor rouxii 
ultrastructure: cyclic AMP and actin cytoskeleton. Protoplasma. 2006 Sep;228(4):189-99.
7. Portela P, Moreno S, Rossi S. Characterization of yeast pyruvate kinase 1 as a protein 
kinase A substrate, and specificity of the phosphorylation site sequence in the whole 
protein. Biochem J. 2006 May 15;396(1):117-26.
8. Valacco MP, Varone C, Malicet C, Cánepa E, Iovanna JL, Moreno S. Cell growth-
dependent subcellular localization of p8. J Cell Biochem. 2006 Apr 1;97(5):1066-79
9. Portela P, Moreno S. Glucose-dependent activation of protein kinase A activity in 
Saccharomyces cersiae and phosphorylation of its TPK1 catalytic subunit. Cell Signal. 
2006 Jul;18(7):1072-86.
10. Espinosa, L., Schebor, C., Buera, P., Moreno, S. and Chirife, J. Inhibition of trehalose 
crystallization by cytoplasmic yeast components Cryobiology , 52: 157-160, 2006.
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http://www.ncbi.nlm.nih.gov/pubmed/19650074
http://www.ncbi.nlm.nih.gov/pubmed/19650074
http://www.ncbi.nlm.nih.gov/pubmed/16226873
http://www.ncbi.nlm.nih.gov/pubmed/16226873
http://www.ncbi.nlm.nih.gov/pubmed/16294328
http://www.ncbi.nlm.nih.gov/pubmed/16294328
http://www.ncbi.nlm.nih.gov/pubmed/16426231
http://www.ncbi.nlm.nih.gov/pubmed/16426231
http://www.ncbi.nlm.nih.gov/pubmed/16426231
http://www.ncbi.nlm.nih.gov/pubmed/16983486
http://www.ncbi.nlm.nih.gov/pubmed/16983486
http://www.ncbi.nlm.nih.gov/pubmed/17080289
http://www.ncbi.nlm.nih.gov/pubmed/17080289
http://www.ncbi.nlm.nih.gov/pubmed/17761146
http://www.ncbi.nlm.nih.gov/pubmed/17761146
http://www.ncbi.nlm.nih.gov/pubmed/18854166
http://www.ncbi.nlm.nih.gov/pubmed/18854166
http://www.ncbi.nlm.nih.gov/pubmed/19411621
http://www.ncbi.nlm.nih.gov/pubmed/19411621
http://www.ncbi.nlm.nih.gov/pubmed/19411621
11. María Pía Valacco, Cecilia L. Varone, Cédric Malicet, Eduardo T. Cánepa, Juan L. 
Iovanna and Silvia M. Moreno. Cell growth-dependent subcellular localization of p8. 
(2006) J Cell Biochem. 97: 1066-79 ISSN 0730-2312
Laboratorio de Biología Molecular: Regulación de la expresión génica y control del 
ciclo celular (Eduardo T. Cánepa)
1. Carcagno Abel L., María F. Ogara, Silvina V. Sonzogni, Mariela C. Marazita, Pablo F. 
Sirkin, Julieta M. Ceruti and Eduardo T. Cánepa. E2F1 transcription is induced by 
genotoxic stress through ATM/ATR activation. IUBMB Life 61 (2009), 537-543.
2. Ceruti Julieta M., María E. Scassa, Mariela C. Marazita, Abel L. Carcagno, Pablo F. 
Sirkin and Eduardo T. Cánepa. Transcriptional upregulation of p19INK4d upon diverse 
genotoxic stress is critical for optimal DNA damage response. Int. J. Biochem. Cell Biol. 41 
(2009), 1344-1353
3. Cánepa Eduardo T., Marıa E. Scassa, Julieta M. Ceruti, Mariela M. Marazita, Abel L. 
Carcagno, Pablo F. Sirkin and Marıa F. Ogara. INK4 proteins, a family of mammalian CDK 
inhibitors with novel biological functions. IUBMB Life 59 (2007), 419-426 
4. Scassa, María E. Mariela C. Marazita, Julieta M. Ceruti, Abel L. Carcagno, Pablo F. 
Sirkin, Marcela González-Cid, Omar P. Pignataro, and Eduardo T. Cánepa. Cell cycle 
inhibitor, p19INK4d, promotes cell survival and decreases chromosomal aberrations after 
genotoxic insult due to enhanced DNA repair. DNA Repair 6 (2007), 626-638
5. Cánepa Eduardo T. Proliferación o quiescencia: una difícil decisión celular. Química 
Viva 6 (2007), publicación online
Laboratorio de Biosensores y bioanálisis (Eduardo Cortón)
1. Ximena C. Abrevaya, Eduardo Cortón and Pablo J. D. Mauas. UV habitability and dM 
stars: an approach for evaluation of biological survival. Proceedings of the International 
Astronomical Union, 2009, 5, 443-445, ISSN: 1743-9213. 
2. Diego J. Kormes and Eduardo Cortón. Development of a Novel Method for in vivo 
Determination of Activation Energy of Glucose Transport across S. cerevisiae Cellular 
Membrane. A Biosensor-like Approach. Sensors, 2009, 9, 1599-1608. ISSN: 1424-8220.
3. X. C. Abrevaya, H. P. Adamo, E. Cortón, P. J. D. Mauas. UV limits of life on extrasolar 
planets: an experiment with halophile archaeabacteria at different UV doses. Boletín de la 
Asociación Argentina de Astronomía, BAAA, 2008, 51, 126-130. ISSN: 1669–9521.
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4. E. Cortón, J. A. García-Calzón, M. E. Díaz-García. Kinetics and Binding Properties of 
Chloramphenicol Imprinted Polymers. Journal of Non-Crystalline Solids, 2007, 353, 974-
980. ISSN: 0022-3093. 
5. Mariela F. Martínez, Astrid Hilding Ohlsson, Alberto A. Viale and Eduardo Cortón. 
Membrane Entrapped Saccharomyces cerevisiae in a Biosensor-like Device as a Generic 
Rapid Method to Study Cellular Metabolism. Journal of Biochemical and Biophysical 
Methods, 2007, 70, 455-464. ISSN: 0165-022X.
6. Santiago Chiappini, Peter Hans Döhmer Pisani and Eduardo Cortón. Characterization 
of a First-Generation Microbial Fuel Cell and its Possible Applications in Environmental 
Chemistry. Proceedings del 5º Congreso Iberoamericano de Sensores, Ibersensor 2006, 
Montevideo, Uruguay, 27 al 29 de septiembre del 2006, 1-6.
REVISTAS DE DIVULGACIÓN CIENTÍFICA
1. La Contaminación de Nuestros Ríos. Estrategias para su Estudio y Uso Racional”. 
Eduardo Cortón. Kuxulkab, México. Volumen 12, Número 23, diciembre del 2006. ISSN: 
1665-0514.
2. Solucionando Grandes Problemas Ambientales con la Ayuda de Pequeños Amigos: las 
Técnicas de Biorremediación”. Eduardo Cortón y Alberto A. Viale. Revista electrónica 
Ecosistemas, año XV Nº 3 / 2006 Septiembre - Diciembre, Páginas 1-10. Asociación 
Española de Ecología Terrestre. ISBN: 1697-2473.
3. INFORMES TÉCNICOS, PARTICIPACIÓN EN MEDIOS MASIVOS DE 
COMUNICACIÓN Y ARTÍCULOS ESCRITOS POR TERCEROS
4. “Bacterias + Barro = Electricidad”. Revista Exactamente, revista de divulgación 
científica de la FCEN, Nro. 43, septiembre 2009, páginas 18-20. Artículo escrito por 
Cecilia Draghi, basado en material y entrevistas proporcionadas y revisadas pro E.C.
5. “Astrobiología”. Participación (entrevistas) en el programa “Recurso Natural”, emitido 
el sábado 19 de septiembre, canal 7, de 11 a 12 hs. 
6. “Transferencia de tecnología. De microscopios y fierros”. Nota acerca del premio 
IB50K (entregado por el Instituto Balseiro, a los mejores proyectos), en Bariloche. El grupo 
dirigido por el Dr. Cortón recibió una mención de honor. Cable Semanal 726, 15 de 
septiembre del 2009, página 4.
7. “Habrá un seguimiento minucioso y con tecnología de las aguas del río Pilcomayo; 
descartan contaminación”. Publicado en La Mañana de Formosa, diario (versión papel y 
electrónico) el 11-09-09. En el artículo se destaca la presentación del proyecto “Biosensores 
de Calidad de Agua”, presentado por el Dr. Cortón el 02 de septiembre en Formosa.
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8. “Proyectan instalar unrobot para alerta temprana de contaminación. Miércoles, 02 de 
Septiembre de 2009”. Nota publicada en la página del canal 11, Lapacho TV, acerca de las 
Jornadas de Calidad del Agua, desarrolladas en Formosa Capital, 02 de septiembre del 
2009.
9. Participación en el programa televisivo “Aportes”, en vivo, emitido el 02 de septiembre 
del 2009, en el canal 11, Lapacho TV, Formosa. Se presentó el proyecto Biosensores de 
Calidad de Agua, con la participación de Marina Jakomin (Subsecretaria de Recursos 
Hídricos, Nación) y el Dr. Oscar Orfeo (CECOAL, CONICET, Corrientes) y el coordinador 
ejecutivo de la Unidad Provincial Coordinadora de Agua (UPCA), Rafael Silva, Pcia. de 
Formosa.
10. Entrega de premio Innovatekne por el Dr. Lino Barañao, Ministro de Ciencia y 
Tecnología de la Nación. http://www.youtube.com/watch?v=d90m9dmxmz8.
11. “Convocatoria Incubacen 2009”. Nota acerca del premio Incubacen 2008 recibido por 
el Laboratorio de Biosensores. Cable Semanal 712, 31 de marzo del 2009, pagina 7.
12. “Cosechan Energía a Partir de Bacterias”. Entrevista filmada en los Laboratorios del 
Depto. de Química Biológica, para el programa televisivo Pura Energía (Canal Metro, 
dirigido por Guillermo Lobo), mayo del 2009. Emitido el 23 de julio del 2009, 8 minutos.
13. “Desarrollan un Biosensor para el Diagnóstico Rápido de Mastitis”. Articulo 
periodístico escrito por Cecilia Draghi (incluye foto color). Diario La Nación, Edición 
Nacional, Suplemento Campo, página 5, sábado 10 de enero del 2009. Examinado y 
corregido técnicamente por E.C. 
14. “Cosechan Energía a Partir de Bacterias”. Radio el Mundo, AM 1070, entrevistado en 
el programa “Ciencia que Habla”, conducido por Cecilia Farré y Gabriela Vizental. Unos 
15 minutos al aire, martes 09 de diciembre del 2008.
15. “Cosechan Energía a Partir de Bacterias”. Articulo periodístico escrito por Cecilia 
Draghi (incluye foto color), acerca del proyecto financiado por la Fundación YPF. Diario 
La Nación, edición Nacional, sección noticias de Ciencia/Salud. Examinado y corregido 
técnicamente por E.C. 17 de noviembre del 2008, página 12.
16. “CUM LAUDE. Astrid Hilding Ohlsson, UBA, Exactas”. Articulo periodístico 
(incluye foto color), acerca del la entrega del Premio Incubacen. Diario Clarín, edición 
Nacional, sección Campus, del domingo 13 de julio del 2008, página 18.
17. “Galardón”, Premio Incubacen. Nota periodística acerca de la entrega del premio 
“Mejor Plan de Negocios.” Incluye foto color. El Cronista Comercial, día 05 de junio de 
2008, Sección Mundo PYME, página VII.
18. “De la Idea a la Empresa”. Artículo escrito por Gabriel Rocca, acerca de la entrega del 
premio al mejor plan de negocios, realizada por el Ministro de Ciencia y Tecnología, Dr. 
Lino Barañao y el Decano Dr. Jorge Aliaga. Premio recibido por el proyecto “Intensive 
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Farm Care Products”, dirigido por el Dr. E.C., acerca de los trabajos realizados en el 
laboratorio del mismo. Examinado y corregido técnicamente por E.C. Cable Semanal 687, 
28 de mayo del 2008, páginas 1-3.
19. “Ganador premio “Mejor Plan de Negocio”. Nota referida al otorgamiento del premio 
al mejor plan de negocios por el proyecto “Intensive Farm Care Products” (proyecto 
mastitis). Nota en la sección Noticias, del 21/05/2008, en al página WEB del 
INCUBACEN, replicada en otros medios como en la página de canal-AR (22/05/2008).
20. “Emprender para Ganar”. Nota referida al otorgamiento de los premios a la Mejor 
Idea-Proyecto (Incubacen-Innova Tekne). El grupo liderado por E.C. obtuvo el primer 
premio por el proyecto titulado “Desarrollo de Biosensores o Lenguas Electrónicas para el 
Diagnostico Rápido de Mastitis Subclínica. Septiembre 2007. Cable Semanal 664, 2 de 
octubre del 2007, pagina 1 y 2
21. Ámbito Financiero 10.10.2007, Ámbito Financiero - Sup. Especial - Pág. 4, Noticias, 
PROYECTOS PREMIADOS, Mastitis.
22. “Científicos Industria Argentina”, programa de Televisión del canal 7, dirigido por el 
Dr. Adrián Paenza. Eduardo Cortón Científico Invitado, programa emitido lunes 24 de 
Septiembre del 2007.
23. “Medir con Bacterias”. “Dialogo con Eduardo Cortón, Biólogo”. Sección Ciencia, 
diario Página 12, miércoles 12 de agosto del 2007. Por Leonardo Moledo.
24. “Laboratorio de Biosensores y Bioanálisis”. Artículo escrito por Patricia Olivilla, 
basado en entrevistas realizadas al Dr. Cortón, acerca de los trabajos realizados en el 
laboratorio del mismo. Examinado y corregido técnicamente por E.C. Cable Semanal 642, 
11 de abril del 2007, pagina 6.
25. “Intentan Medir la Contaminación del Agua… con Bacterias”. Artículo escrito por 
Cecilia Draghi, basado en entrevistas realizadas al Dr. Cortón, acerca de los trabajos 
realizados en el laboratorio del mismo. Examinado y corregido técnicamente por E.C. 
Publicado en el diario de edición nacional “La Nación”, página 13, del 16 de junio de 2006. 
Artículo replicado en varios medios electrónicos, incluyendo su traducción al portugués. 
26. “Cuando las bacterias “trabajan” para el hombre.” Artículo escrito por Cecilia Draghi, 
basado en entrevistas realizadas al Dr. Cortón, acerca de los trabajos realizados en el 
laboratorio del mismo. Examinado y corregido técnicamente por E.C., Centro de 
Divulgación Científica-SEGB-FCEyN, martes 18 de julio de 2006.
27. “Pila de Microbios”, articulo de divulgación en la revista “NEO”, Nro. 16, julio del 
2006, páginas 102-103, ISSN 1669-1687. Artículo escrito por Cecilia Draghi, basado en 
entrevistas realizadas al Dr. Cortón, acerca de los trabajos realizados en el laboratorio del 
mismo. Examinado y corregido técnicamente por E.C.
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Laboratorio de Disturbios metabólicos por xenobióticos (Leonor San Martín de Viale/ 
Carlos Lantos)
1. Altuna ME, Mazzetti, M.B., Rago LF, San Martín de Viale LC and Damasco MC. 
Hepatic 11 beta-hydroxysteroid dehydrogenase 1 involvement in alterations of glucose 
metabolism produced by acidotic stress in rat . J. Physiol Biochem 65, 329-338 (2009) 
ISSN: 1138-7548, Official Journal of the University of Navarra, Spain
2. Lelli, S.M., Mazzetti, M.B. and San Martin de Viale, L.C. “Hepatic alteration of 
tryptophan metabolism in an acute porphyria model. Its relation with the gluconeogenic 
blockage”. Biochem. Pharmacol. 75, 704-712 (2008) ISSN 006-2952, Editorial Elsevier 
Ireland Ltd. Co. Clare 
3. Llambías, E.B.C., Mazzetti, M.B., Lelli, S.M.,. Aldonatti, C. and San Martin de Viale, 
“Melatonin formation in pineal glands from rats with HCB experimental porphyria” L.C. 
International Journal of Toxicology 26: 545-551 (2007). ISSN 1091-5818, The official 
Journal ofAmerican College of Toxicology, Francis & Taylor Group, London, England
4. Lelli, SM., Ceballos NR, Mazzetti, MB, Aldonatti, and San Martín de Viale, LC 
Hexachlorobenzene as hormonal disruptor- studies about glucocorticoid: Their hepatic 
receptor, adrenal synthesis and plasma levels in relation to impaired gluconeogenesis”. 
Reino Unido. Inglaterra. Biochem Pharmacol. 73: 873-879 (2007) ISSN 006-2952. Elsevier 
Ireland Ltd. Co. Clare, Ireland.
Laboratorio de Enzimología, Estrés oxidativo y Metabolismo (María del Carmen 
Ríos)
1. Causin H.F., Roberts I.N., Criado M.V., Gallego S.M., Pena L.B., Ríos M.C., Barneix 
A.J.Changes in hydrogen peroxide homeostasis and cytokinin levels contribute to the 
regulation of shade-induced senescence in wheat leaves. Plant Science 2009. 
doi:10.1016/j.plantsci.2009.08.014. ISSN: 0168-9452.
2. Sabatini S. E., Chaufan G., Juárez A. B., Coalova I., Bianchi L., Eppis M.R., Ríos de 
Molina M.C. Dietary copper effects in the estuarine crab, Neohelice (Chasmagnathus) 
granulata, maintained at two different salinities. Compar. Biochem. Physiol., Part C. 150 
(2009) 521–527. doi:10.1016/j.cbpc.2009.07.006. ISSN: 1532-0456. 
3. Sabatini S. E., Juárez A. B., Eppis M. R., Bianchi L., Luquet C. M., Ríos de Molina M. 
C. Oxidative stress and antioxidant defenses in two green microalgae exponed to copper. 
Ecotoxicol. Environ. Safety. 72 (2009) 1200-1206. doi:10.1016/j.ecoenv.2009.01.003.ISSN: 0147-6513.
4. Miller E. A., Ríos de Molina M. C., Domínguez G, Guerra L. N.Thyroid hormone 
effect in human hepatocytes. Redox Report, 13 (4) (2008) 185-191. ISSN 1351-0002.
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5. Rocchetta I., Leonardi P. I., Amado Filho G. M., Rìos de Molina M.C., Conforti V. 
Ultraestructure and X-ray microanálisis of Euglena gracilis (Euglenophyta) under 
chromium stressPhycologia 46 (3) (2007) 300-306. ISSN: 0031-8884.
6. Juárez A., Aldonatti C., Vigna S., Ríos de Molina M.C.Studies on Uroporphyrinogen 
decarboxylase (UroD) from Chlorella kessleri (Trebouxiophyceae, Chlorophyta). Can. J. 
Microbiology. 53 (2) (2007) 303-315. ISSN: 1480-3275.
7. Chaufan G., Juárez A., Basack S., Ithuralde E., Sabatini S. E., Genovese G., Oneto 
M.L., Kesten E., Ríos de Molina M.C. Toxicity of hexachlorobenzene and its transference 
from microalgae (Chlorella kessleri) to crabs (Chasmagnathus granulatus). Toxicology 227 
(2006) 262-270. ISSN 0300-483X.
8. Riva D.A., Ríos de Molina M.C., Rocchetta I., Gerhardt E., Coulombié F.C., Mersich 
S.E. Oxidative stress in Vero cells infected with vesicular stomatitis virus. Intervirology, 49 
(2006) 294-298. ISSN 0300-5526/06/0495-0294
9. Rocchetta I., Ruiz L., Ríos de Molina M.C., Conforti V. Chromium toxicity to Euglena 
gracilis strains depending on the physicochemical properties of the culture medium. Bull. 
Environ. Contam. Toxicol., 76 (2006) 512-521. ISSN 0007-4861.
10. Rocchetta I., Mazzuca M., Conforti V., Ruiz L.B., Balzaretti V., Ríos de Molina M.C. 
Effect of chromium on the fatty acid composition of two strains of Euglena gracilis. 
Environmental Pollution, 141(2) (2006) 353-358. ISSN 0269-7491.
11. Julianelli Vanina L., Guerra Liliana N.*, Calvo Juan C.*. Cell-cell communication 
between Mouse mammary epithelial cells and 3T3-L1 preadipocytes: Effect on triglyceride 
accumulation and cell proliferation. Biocell, 2007, 31: 237-245.
12. L N Guerra, E. Miler, M. Moiguer, S. Karner, A. Orlando, H. Fideleff and J. Burdman 
Telomerase Activity in Fine Needle Aspiration Biopsy Samples: Application to Diagnosis 
of Human Thyroid Carcinoma. Clinica Chimica Acta, ISSN 0009-8981, 2006, 370: 180-
184.
13. Liliana N. Guerra, Ma del Carmen Ríos de Molina, Eliana A. Miler, Silvia Moiguer, 
Mirta Karner and José A. Burdman. Antioxidants and methimazole in the treatment of 
Graves’ disease: effect on urinary maondialdehyde levels. Clinica Chimica Acta, ISSN 
0009-8981, 2005, 352: 115-120. 
Capítulos de libros
14. Chaufan G., Juárez A. B., Sabatini S. E., Ríos de Molina M.C Impacto del 
hexaclorobenceno sobre el cangrejo Chasmagnathus granulatus (=Neohelice granulata) de 
la Bahía de Samborombón.. En: RED CYTED - Programa Iberoamericano de Ciencia y 
Tecnología para el Desarrollo. 406RT0285, Fernández Reyes L., Volpedo A., Rial A. (eds.). 
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Efecto de cambios globales sobre humedales de Iberoamérica. 2008, pp. 191-205. ISBN 
978-987-05-5533-9.
15. Juárez A.B., Schiariti A., Aldonatti C., Rodríguez M.C., Ríos de Molina M.C.Estudios 
de toxicidad celular de contaminantes ambientales. En: Herkovits J. (ed.) Salud Ambiental 
y Humana. Una visión Holística. Libro de SETAC (Sociedad de Toxicología Ambiental y 
Química) América Latina. 2006, pp. 69-72. ISBN 10: 987-05-1959-8 y ISBN 13:978-987-
05-1059-1. 
16. Capítulo: Telomerase Activity: Application to Diagnosis of human carcinoma. Libro: 
DNA-Directed DNA Polymerase Editorial: Nova Science Publisher, Inc, (2009) Web: 
www.novapublisher.com
Revistas de divulgación científica
17. Scaglia, HE; Viola, AM; Guevel, L; Guerra, LN; Mohr, AL; Jozami, LS; Aquilano, DR; 
Scaglia, Perfil androgenico en mujeres hirsutas. Modificaciones de sus niveles en la fase 
lutea. J. Revista Argentina de Endocrinología y Metabolismo, ISSN: 0326-4610, 2007, 44: 
233- 241.
Laboratorio de Expresión Génica en Mama y Apoptosis (Adalí Pecci)
1. Pecci A, Alvarez LD, Veleiro AS, Ceballos NR, Lantos CP, Burton G. New lead 
compounds in the search for pure antiglucocorticoids and the dissociation of 
antiglucocorticoid effects. 2009 J Steroid Biochem Mol Biol. 113(3-5):155-62. ISSN: 
0960-0760. 
2. Romorini L, Coso OA, Pecci A. Bcl-XL mediates epidermal growth factor dependent 
cell survival in HC11 mammary epithelial cells. 2009 Biochim Biophys Acta. 1793(3):496-
505. ISSN 0304-4165
3. Alvarez LD, Martí MA, Veleiro AS, Misico RI, Estrin DA, Pecci A, Burton G. 
Hemisuccinate of 21-Hydroxy-6,19-Epoxyprogesterone: A Tissue-Specific Modulator of 
the Glucocorticoid Receptor. 2008 ChemMedChem. 3(12):1869-77. ISSN: 1860-7179. 
4. L. Rocha Viegas, E. Hoijman, M. Beato and A. Pecci. Mechanisms involved in tissue-
specific apopotosis regulated by glucocorticoids 2008 J Steroid Biochem Mol Biol. 
109:273-8. ISSN:0960-0760. 
5. L.D. Alvarez, M.A. Martí, A.S. Veleiro, D.M. Presman, D.A. Estrín, A. Pecci and G. 
Burton. Exploring the molecular basis of action of the passive antiglucocorticoid 21-
hydroxy-6,19-epoxyprogesterone. 2008. J Med Chem 51:1352-60. ISSN: 0022-2623. 
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http://www.novapublisher.com/
6. Rodríguez Granillo, J.C. Boffi, L. Barañao, E. Kordon, A. Pecci and A.
7. Guberman. STAT5 transcriptional activity is impaired by LIF in a mammary epithelial 
cell line. 2007 Biochem. & Bioph. Res. Comm. (356:727). ISSN:0006-291X
8. L. Rocha Viegas, G.P. Vicent, J.L. Barañao, M. Beato and A. Pecci. Glucocorticoids 
repress bcl-X expression in lymphoid cells through the recruitment of STAT 5 B to the 
distal promoter P4 2006 J. Biological Chemistry (281:33959. ISSN: 0021-9258. 
9. D. Presman, E. Hoijman, N.R. Ceballos, M.D. Galigniana and A. Pecci. Melatonin 
inhibits glucocorticoid receptor nuclear translocation in mouse thymocytes 2006 
Endocrinology (147:5452)ISSN: 0013-7227
Sistema de señales intracelulares y diferenciación celular (María del Carmen Vila)
1. Martini, Claudia. N., Romero, Damian, Yanes, Licy L. y M.C. Vila. Induction of 5-
aminolevulinate-synthase by activators of steroid biosynthesis. Life Sciences 81, 19-25 
(2007) 
2. PKA-dependent and independent cAMP signalling in 3T3-L1 fibroblasts 
differentiation. Martini, Claudia, Plaza, María Victoria y M.C.Vila 
Mol. Cell Endocrinol. 298, 42-47 (2009) 2008 Oct 25 
Biología Celular y Molecular (Mario Galigniana/ Martín Monte)
1. M. Monte, M. Simonatto, L.Y. Peche, D.R. Bublik, S. Gobessi, M.A. Pierotti, M. 
Rodolfo and C. Schneider. MAGE-A tumor antigens target p53 transactivation function 
through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. 
Proc.Natl.Acad.Sci (USA), 103: 11160-11165, 2006. 1. M. Monte, M. Simonatto, L.Y. 
Peche, D.R. Bublik, S. Gobessi, M.A.
2. Pierotti, M. Rodolfo and C. Schneider. MAGE-A tumor antigens target p53 
transactivation function through histone deacetylase recruitment andconfer resistance to 
chemotherapeutic agents. Proc.Natl.Acad.Sci (USA),103: 11160-11165, 2006.
3. Salatino M, Beguelin W, Peters MG, Carnevale R, Proietti CJ, Galigniana MD, Vedoy 
CG, Schillaci R, Charreau EH, Sogayar MC, Elizalde PV. Progestin-induced caveolin-1 
expression mediates breast cancer cell proliferation. Oncogene. 2006; 25(59):7723-39. 
4. Aviezer-Hagai K, Skovorodnikova J, Galigniana M, Farchi-Pisanty O, Maayan 
5. E, Bocovza S, Efrat Y, von Koskull-Döring P, Ohad N, Breiman A. Arabidopsis 
immunophilins ROF1 (AtFKBP62) and ROF2 (AtFKBP65) exhibit tissue specificity, are 
heat-stress induced, and bind HSP90. Plant Mol Biol. 2007 Jan;63(2):237-55. 2006.
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6. Piwien Pilipuk G, Vinson GP, Sanchez CG, Galigniana MD. Evidence forNL1-
independent nuclear translocation of the mineralocorticoid receptor. Biochemistry. 2007 
Feb 6;46(5):1389-97. 
7. Colo GP, Rubio MF, Nojek IM, Werbajh SE, Echeverría PC, Alvarado CV, Nahmod 
VE, Galigniana MD, Costas MA. The p160 nuclear receptor co-activator RAC3 exerts an 
anti-apoptotic role through a cytoplasmatic action. Oncogene. 2008;27(17):2430-44. 
8. Gallo LI, Ghini AA, Piwien Pilipuk G, Galigniana MD. Differential Recruitment of 
tetratricorpeptide repeat domain immunophilins tothe mineralocorticoid receptor 
influences both heat-shock protein 90-dependent retrotransport and hormone-dependent 
transcriptional activity. Biochemistry. 2007;46(49):14044-57.
9. Echeverría PC, Mazaira G, Erlejman A, Gomez-Sanchez C, Piwien Pilipuk G, 
Galigniana MD. Nuclear import of the glucocorticoid receptor-hsp90 complex through the 
nuclear pore complex is mediated by its interaction with Nup62 and importin beta. Mol 
Cell Biol. 2009; 29(17):4788-97.
Regulación de la expresión génica en el crecimiento, supervivencia y diferenciación 
celular (Lino Barañao)
1. Scassa M.E., Fernández Espinosa D., Questa M., Videla Richardson G.,Losino N., 
Luzzani C., Guberman A.S., Grancelli H., Sevlever G., Miriuka S.G.. (2009) 
Diferenciación en cardiomiocitos a partir de células madre embrionarias humanas. Rev. 
Argent. Cardiol.; 77 458-464.
2. Rodríguez Granillo, A.; Boffi J. C.; Barañao L.; Kordon E., Pecci A., Guberman, A. 
(2007). STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line. 
Biochemical and Biophysical Research Communications 356 727-732.
Laboratorio de Regulación génica en levaduras (Susana Correa/ Mariana Bermudez 
Moretti) 
1. Bermúdez Moretti M., Maskin L., Gudesblat G., Correa García S. and Iusem N. ASR1, 
a stress-induced tomato protein, protects yeast from osmotic stress. Physiologia Plantarum 
127, 111-118, 2006.
2. Luzzani, C., Cardillo, S. B., Bermudez Moretti, M. & Correa Garcia, S. New insights 
into the regulation of the Saccharomyces cerevisiae UGA4 gene: two parallel pathways 
participate in carbon-regulated transcription. Microbiology 153, 3677-84. 2007.
3. Perullini, M., Jobbágy, M., Bermúdez Moretti, M., Correa García, S. and Bilmes S.A. 
Optimizing silica encapsulation of living cells: in situ evaluation of cellular stress. Chem. 
Mater. 20 (9), 3015-3021, 2008.
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Grupo interdisciplinario de Bioquímica Estructural (Adrián Turjanski/ Valeria Levi)
1. De Biase, P.; Alvarez Paggi, D; Doctorovich, F; Hildebrandt, P; Estrin, D. A; Murgida, 
D,H; Marti, M,A. Molecular Basis for the Electric Field Modulation of Cytochrome c 
Structure and Function. J. Am. Chem. Soc. 2009. 131 (44), 16248-56.
2. Leonardo Boechi, Pau Arroyo Mañez, Javier Luque, Marcelo A. Marti and Dario A. Es
trin. 
Unraveling the molecular basis for ligand binding in truncated hemoglobin: the trHbO B. s
ubtils case. Proteins, Struc. Func. And Bionf. 2010;78(4):962-70.
3. Ariel Lewis-Ballester, Dipanwita Batabyal, Tsuyoshi Egawa, Changyuan Lu, Yu Lin, 
Marcelo A. Marti, Luciana Capece, Dario A. Estrin and Syun-Ru Yeh. Evidence for a 
Ferryl Intermediate in a Heme-based Dioxygenase. Proc. Natl. Acad. Sci USA. 2009, 
106(41) 17371-17376.
4. Ariel A. Petruk, Marcelo A. Marti, and Rosa María S. Alvarez. Thyroid Hormones 
Interactions with DMPC bilayers. A Molecular Dynamics Study. J. Phys. Chem B. 2009, 
113(40) 13357-64.
5. Diego F. Gauto, Santiago Di Lella, Carlos M. A. Guardia, Darío A. Estrin and Marcelo 
A. Martí. Carbohydrate-binding proteins: Dissecting ligand structures through solvent 
environment occupancy. J. Phys. Chem B. 2009 113(25) 8717-8724.
6. Lama A, Pawaria S, Bidon-Chanal A, Anand A, Gelpí JL, Arya S, Martí MA, Estrin 
DA, Luque FJ, Dikshit KL. Role of Pre-A motif in nitric oxide scavenging by truncated 
hemoglobin, HbN, of mycobacterium tuberculosis. J Biol Chem. 2009 284(21), 14457-
14468.
7. Giordano D, Boechi L, Vergara A, Martí MA, Samuni U, Dantsker D, Grassi L, Estrin 
DA, Friedman JM, Mazzarella L, di Prisco G, Verde C. The hemoglobins of the sub-
Antarctic fish Cottoperca gobio, a phyletically basal species-oxygen-binding equilibria, 
kinetics and molecular dynamics. FEBS J. 2009;276(8):2266-77.
8. D Alvarez Paggi, DF. Martín, A Kranich, P Hildebrandt, MA Martí,DH Murgida. 
Computer simulation and SERR detection of cytochrome c dynamics at SAM-coated 
electrodes Elctrochimica Acta. 2009, 54(21) 4963-70. 
9. Martí MA, Estrin DA, Roitberg AE. Molecular Basis for the pH Dependent Structural 
Transition of Nitrophorin 4. J Phys Chem B.2009;113(7):2135-2142. 
10. Swails JM, Meng Y, Walker FA, Marti MA*, Estrin DA, Roitberg AE. pH-dependent 
mechanism of nitric oxide release in nitrophorins 2 and 4. J Phys Chem B. 
2009;113(4):1192-201.
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11. Capece L, Marti MA, Bidon-Chanal A, Nadra A, Luque FJ, Estrin DA. High pressure 
reveals structural determinants for globin hexacoordination: Neuroglobin and myoglobin 
cases. Proteins. 2009, 75(4) 885-894.
12. L. Capece, D.A Estrin and M.A. Marti. Dynamical characterization of the Heme NO 
Oxygen binding (H-NOX) domain. Insight into soluble guanylate cyclase allosteric 
transition. Biochemistry 2008; 47(37):9793-802.
13. L.L. Perissinotti, M.A. Marti, F. Doctorovich, F.J. Luque and D.A. Estrin. A 
microscopic study of the deoxy-hemoglobin catalyzed generation of nitric oxide from 
nitrite anion. Biochemistry, 2008; 47(37):9793-802. 
14. Marti, MC. González Lebrero, AE. Roitberg and DA Estrin. J. Bond or Cage Effect: 
How Nitrophorins Transport and Release Nitric Oxide MA. Am. Chem. Soc, 2008; 130(5); 
1611-1618.
15. G. Pierdominici-Sottile, MA. Martí and J. Palma. The role of residue Thr122 of 
methylamine dehydrogenase on the proton transfer from the iminoquinone intermediate to 
residue Asp76. Chem Phys Lett. 2008, Vol. 456 (4), 243-246
16. Boechi L, Martí MA, Milani M, Bolognesi M, Luque FJ, Estrin DA. Structural 
determinants of ligand migration in Mycobacterium tuberculosis truncated hemoglobin O. 
Proteins. 2008
17. Alvarez LD, Martí MA, Veleiro AS, Misico RI, Estrin DA, Pecci A, Burton G. 
Hemisuccinate of 21-hydroxy-6,19-epoxyprogesterone: a tissue-specific modulator of the 
glucocorticoid receptor. ChemMedChem. 2008 (12):1869-77
18. Lautaro D. Álvarez, Marcelo A. Martí, Adriana S. Veleiro, Diego M. Presman, Darío A. 
Estrin, Adalí Pecci, and Gerardo Burton. Exploring the Molecular Basis of Action of the 
Passive Antiglucocorticoid 21-Hydroxy-6,19-epoxyprogesterone J. Med. Chem. 2008 
13;51(5):1352-60. 
19. MA Martí, A. Bidon-Chanal, A. Crespo, S. Yeh, V. Guallar, F. J. Luque, D. A. Estrin. 
Mechanism of Product Release in NO detoxification from Mycobacterium tuberculosis 
Truncated Hemoglobin N. J. Am. Chem. Soc. 2008; 130(5); 1688-1693. 
20. Alejandro D. Nadra, Marcelo A. Martí, Alessandra Pesce, Martino Bolognesi, Darío A. 
Estrin. Exploring the molecular basis of heme coordination in human neuroglobin. Proteins. 
2008, 71(2):695-705.
21. Tioni MF, Llarrull LI, Poeylaut-Palena AA, Martí MA, Saggu M, Periyannan GR, Mata 
EG, Bennett B, Murgida DH, Vila AJ. Trapping and characterization of a reaction 
intermediate in carbapenem hydrolysis by B. cereus metallo-beta-lactamase. J Am Chem 
Soc. 2008;130(47):15852-63.
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22. Di Lella S, Marti MA, Alvarez RM, Estrin DA, Ricci JC.Characterization of the 
Galectin-1 Carbohydrate Recognition Domain in Terms of Solvent Occupancy. J Phys 
Chem B. 2007, 111, (25) 7360-7366
23. Marcelo A. Marti, Luciana Capece, Damian E. Bikiel, Bruno Falcone, and Dario A 
Estrin. Oxygen Affinity Controlled by Dynamical Distal Conformations: The Soybean 
Leghemoglobin and the Paramecium Caudatum Hemoglobin cases. Proteins 2007, 
27;68(2):480-487.
24. Bidon-Chanal, Marcelo A. Martí, Darío A. Estrin, and F. Javier Luque. Dynamical 
Regulation of Ligand Migration by a Gate-Opening Molecular Switch in Truncated 
Hemoglobin-N from Mycobacterium Tuberculosis Axel J Am Chem Soc. 2007, 
30;129(21):6782-6788. 
25. Sebastián A. Suárez, Marcelo A. Martí, Pablo M. De Biase, Darío A. Estrin, Sara E. 
Bari and Fabio Doctorovich. HNO trapping and assisted decomposition of nitroxyl donors 
by ferric hemes Polyhedron 2007, 26(16):4673-4679. 
26. Capece L, Marti MA, Crespo A, Doctorovich F, Estrin DA. Heme protein oxygen 
affinity regulation exerted by proximal effects. J Am Chem Soc. 2006,128(38):12455-61
27. Crespo A, Marti MA, Roitberg AE, Amzel LM, Estrin DA. The catalytic mechanism of 
peptidylglycine alpha-hydroxylating monooxygenase investigatedby computer simulation 
J Am Chem Soc. 2006;128(39):12817-28.
28. Damián E. Bikiel, Leonardo Boechi, Luciana Capece, Alejandro Crespo, Pablo M. De 
Biase, Santiago Di Lella, Mariano C. González Lebrero, Marcelo A. Martí, Alejandro D. 
Nadra, Laura L. Perissinotti, Damián A. Scherlis and Darío A. Estrin. Modeling heme 
proteins using atomistic simulations Phys. Chem. Chem. Phys. 2006
29. Bidon-Chanal, A. Marti, MA. Crespo, A. Milani, M. Orozco, M. Bolognesi, M. Luque, 
FJ and Estrin DA. Ligand-induced dynamical regulation of NO conversion in 
Mycobacterium Tuberculosis truncated-hemoglobin N Proteins, 2006;64(2):457-64. 
30. Xiong, H. Crespo, A. Marti, MA. Estrin DA, Roitberg AE. Free Energy Calculations 
with Non-equilibrium Methods: Applications of the Jarzynski Relationship. Theoretical 
Chemistry Accounts, 2006, 106, 338-346.
31. Marti MA, Crespo A, Capece L, Boechi L, Bikiel DE, Scherlis DA, Estrin DA. 
Dioxygen affinity in heme proteins investigated by computer simulation. J. Inorg. Biochem. 
2006, 100(4):761-70.
32. Marti MA, Bikiel DE, Crespo A, Nardini M, Bolognesi M, Estrin DA. Two distinct 
heme distal site states define Cerebratulus lacteus mini-hemoglobin oxygen affinity. 
Proteins. 2006;62(3):641-8.
13
33. Capece L, Marti MA, Bidon-Chanal A, _Nadra A_, Luque FJ, Estrin DA. High 
pressure reveals structural determinants for globinhex acoordination: Neuroglobin and 
myoglobin cases”. Proteins. 2008 Oct 15.
34. Marcaida MJ, Prieto J, Redondo P, _Nadra AD_, Alibés A, Serrano L, Grizot S, 
Duchateau P, Pâques F, Blanco FJ, Montoya G.Crystal structure of I-DmoI in complex with 
its target DNA provides new insights into meganuclease engineering.” Proc Natl Acad Sci 
U S A. 2008 Nov 4;105(44):16888-93. 
35. Alejandro D. Nadra_, Marcelo A. Marti, Alessandra Pesce, Martino Bolognesi, and 
Dario A. Estrin. Exploring the molecular basis of heme coordination in human 
neuroglobin”. _ Proteins: Structure, Function, and Bioinformatics. Proteins. 2008 May 
1;71(2):695-705. 
36. Bikiel DE, Boechi L, Capece L, Crespo A, De Biase PM, Di Lella S, González Lebrero 
MC, Martí MA, _Nadra AD_, Perissinotti LL, Scherlis DA, Estrin DA. Modeling heme 
proteins using atomistic simulations.” Phys Chem Chem Phys. 2006 Dec 28;8(48):5611-28 
37. Maia Brunstein, Luciana Bruno, Marcelo Desposito, Valeria Levi. Anomalous 
dynamics of melanosomes driven by myosin-V in Xenopus laevis melanophores. Biophys J 
97:1548-57 2009.
38. L. Bruno, V. Levi, M. Brunstein and M. A. Despósito. Intracellular actin-based 
transport mediated by molecular motors: transition to superdiffusive behavior. Phys Rev E 
Stat Nonlin Soft Matter Phys. 80(1 Pt 1):011912. 2009.
39. Javier Baier, Cristina Gallegos, Valeria Levi and Francisco Barrantes. Cholesterol 
modulates nicotinic acetylcholine receptor mobility at the cell membrane. Eur Biophys J. 
39(2):213-27. 2009.
40. Luciana Bruno, Mercedes Echarte and Valeria Levi. Exchange of Microtubule 
Molecular Motors During Melanosome Transport in Xenopus laevis Melanophores is 
Triggered by Collisions with Intracellular Obstacles. Cell Biochem Biophys. 52(3):191-
201. 2008.
41. Levi V. Villamil Giraldo A, Castello PR, Rossi JP, Gonzalez Flecha FL. Effects of 
phosphatidylethanolamine glycation on lipid-protein interactions and membrane protein 
thermal stability. Biochem J. Nov 15;416(1):145-52. 2008.
42. Levi V, Gratton E. Chromatin dynamics during interphase explored by single particle 
tracking. (Review) Chromosome Research and Technique 16:439-449 2008.
43. Levi V, Gratton E. Exploring dynamics in living cells by tracking single particles. 
(Review) Cell Biochemistry and Biophysics 48(1):1-15. 2007. 
44. Levi V, Gelfand VI, Serpinskaya AS, Gratton E. Melanosomes Transported by Myosin 
V in Xenopus Melanophores Perform Slow 35 nm Steps. Biophys J. 90:L7-9. 2006.
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45. Levi V, Serpinskaya AS, Gratton E, Gelfand V. Organelle transport along microtubules 
in Xenopus melanophores: evidence for cooperation between multiple motors. Biophys J. 
90:318-327. 2006.
46. Turjanski AG, Hummer G, Gutkind JS. How mitogen-activated protein kinases 
recognize and phosphorylate their targets: A QM/MM study. J Am Chem Soc. 2009 May 
6;131(17):6141-8.
47. Amanda P. Skoumbourdis; Christopher A. Leclair; Eduard Stefan; Adrian G. Turjanski; 
William Maguire; Steven A. Titus; Ruili Huang; Douglas S. Auld; James Inglese; 
Christopher P. Austin; Stephen W. Michnick; Menghang Xia; Craig J. Thomas. Exploration 
and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 
inhibitors. Bioorganic & Medicinal Chemistry Letters. 2009.
48. Jaime G. Mayoral, Marcela Nouzova, Michiyo Yoshiyama, Tetsuro Shinoda, Salvador 
Hernandez-Martinez, Elena Dolghih, Adrian G. Turjanski, Adrian E. Roitberg, Horacio 
Priestap, Mario Perez, Lucy Mackenzie, Yiping Li, Fernando G. Noriega. Molecular and 
functional characterization of a juvenile hormone acid methyltransferase expressed in the 
corpora allata of mosquitoes. Insect Biochemistry and Molecular Biology. 2009. vol. 39 n. 
1 p.31-37 ISSN 0965-1748 
A. G. Turjanski, J. S. Gutkind, R. Best, G. Hummer. Binding Induced Folding of a 
Natively Unstructured Transcription Factor. PLOS Computational Biology, 4(4): e1000060.
A. G. Turjanski, J P. Vaqué, J.S. Gutkind. MAPKs and the control of nuclear events. 
Oncogene. 2007 May 14;26 (22):3240-53
49. VM Sanchez, A. Crespo, JS. Gutkind, AG. Turjanski. Investigation of the Catalytic 
Mechanism of Farnesyl Pyrophosphate Synthase by Computer Simulation. Journal of 
Physical Chemistry B, 2006 Sep 14;110(36):18052-7.
50. L. Sigman, VM Sanchez, AG. Turjanski. Characterization of the farnesyl 
pyrophosphate synthase of Trypanosoma cruzi by homology modeling and molecular 
dynamics. Journal of Molecular Graphics and Modeling. 2006, 25, 345-352.
51. Clara Smal, Diana E. Wetzler, Karina I. Dantur, Lucia B. Chemes, María M. García-
Alai, Mariano Dellarole, Leonardo G. Alonso, Kevin Gaston and Gonzalo Prat-Gay. The 
human papillomavirus E7-E2 interaction mechanism reveals a finely tuned regulatory 
system for modulating available E7 and E2 protein levels. Biochemistry, 2009, 48 (50), pp 
11939–11949
52. Diana E. Wetzler, Mariana Gallo, Riccardo Melis, Tomasso Eliseo, Alejandro D. 
Nadra, Diego U. Ferreiro, Maurizio Paci, Ignacio E. Sánchez, Daniel O. Cicero, Gonzalo de 
Prat Gay. A strained DNA binding helix is conserved for site recognition, folding 
nucleation, and conformational modulation. Biopolymers, 2009, 91(6), 432-443.
15
53. Diana E. Wetzler, Eduardo M. Castaño, Gonzalo de Prat-Gay. Quasi-spontaneous 
amyloid route in a dna binding gene regulatory domain of the papillomavirus hpv16 e2 
protein. Protein Sicence, 2007, 16(4), 744-754.
54. D. E. Wetzler, D. García-Fresnadillo, G. Orellana. A Solid Reference System for 
Photosensitized 1O2 Production Measurements. P.C.C.P, 2006, 8, 2249-2256
55. Maria M. García-Alai, Mariana Gallo, Marcelo Salame, Diana E. Wetzler, Alison A. 
McBride, Maurizio Paci, Daniel O. Cicero, and Gonzalo de Prat-Gay. Molecular basis for 
phosphorylation dependent PEST mediated protein turnover. Structure, 2006, 14, 309-319.
Capitulos de libro
56. 3-Dimensional particle tracking in a laser scanning fluorescence microscope. Valeria 
Levi and Enrico Gratton. En: Single Particle Tracking and Single Molecule Energy Transfer 
published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim ("WILEY-VCH"). (in 
press)
57. Exploring the Nitric Oxide Detoxification Mechanism of Mycobacterium tuberculosis 
Truncated Haemoglobin N, A. Bidon-Chanal, M.A. Marti, D.A. Estrin, and F.J. Luque. In 
Self organization of Molecular system: From Molecules and Clusters to Nanotubes and 
Proteins. Edited by N Russo, VY Antochenko and E Kryachko. NATO Science for Peace 
and Security Series A: Chemistry and Biology. Springer 2009, p33-47.
58. NO reactivity with globins as investigated through computer simulation. M.A. Marti, 
L. Capece, A. Bidon-Chanal, A. Crespo, V. Guallar, F.J. Luque,and D. A. Estrin. Globins 
and Other Nitric Oxide-Reactive Proteins, Part B Edited by R.k Poole for Methods in 
Enzymology Volumen 437 Páginas 477-98 Elsevier 2008. 
Trabajos publicados en Revistas Nacionales o de Divulgación
59. La bioinformática estructural o la realidad virtual de los medicamentos. Marcelo A. 
Martí y Adrian A. Turjanski. Quimica Viva, Número 1, Año 8, Abril 2009.
Regulación de la respuesta inmune celular por proteínas de señalización (Verónica 
García)
1. María F. Quiroga, Virginia Pasquinelli, Gustavo J. Martínez, Javier O. Jurado, Liliana 
Castro Zorrilla, Rosa M. Musella, Eduardo Abbate, and Verónica E. García. Inducible 
Costimulator (ICOS): a modulator of IFN- production in human tuberculosis. The 
Journal of Immunology, 176:5965-5974. 2006. ISSN: 0022-1767.
16
2. Verónica E. García, H. Eduardo Chuluyan. SLAM and CD31: signaling molecules 
involved in cytokine secretion during the development of innate and adaptive immune 
responses. Cytokine and Growth Factor Reviews, 18(1-2): 85-96, 2007. ISSN: 1359-6101
3. Paulo C. Maffia, Sandra E. Zittermann, M. Lucila Scimone, Nancy Tateosian, Nicolás 
Amiano, Diego Guerrieri, Viviana Lutzky, Diego A. Rosso, Horacio E. Romeo, Verónica E. 
García, Andrew C. Issekutz and H. Eduardo Chuluyan. Neutrophil elatase converts 
immature dendritic cells into TGF-B secreting cells and reduces allostimulatory ability. 
The American Journal of Pathology, 2007 Sep;171(3):928-37 ISSN: 0002-9440. 
4. Maria F. Quiroga, Javier O. Jurado, Gustavo J. Martínez, Virginia Pasquinelli, Rosa M. 
Musella, Eduardo Abbate, Andrew C. Issekutz, Peter A. Sieling, H. Eduardo Chuluyan, 
Verónica E. García. Cross-talk between CD31 and the signaling lymphocytic activation 
molecule-associated protein during interferon- gamma production against Mycobacterium 
tuberculosis. The Journal of Infectious Diseases, 2007, 196:1369-1378. ISSN: 0022-1899. 
5. Ankita Garg, Peter F. Barnes, María F. Quiroga, Sugata Roy, Shiping Wu, Verónica E. 
García, Steven E. Weis, and Ramakrishna Vankayalapati. Mannose-capped 
lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in 
human Mycobacterium tuberculosis infection. European Journal of Immunology, 2008, 
38:459-69. ISSN: 0014-2980
6. Javier O. Jurado, Ivana B. Alvarez, Virginia Pasquinelli, Gustavo J. Martínez, María F. 
Quiroga, Eduardo Abbate, Rosa M. Musella, H. Eduardo Chuluyán, Verónica E. García. 
PD-1:PD-L1/PD-L2 pathway inhibits T cell effector functions during human tuberculosis”. 
The Journal of Immunology. 2008. Vol: 181: 116-125.
7. Sonia A. Gómez, Claudia L. Argüelles, Diego Guerrieri, Nancy L. Tateosián, Nicolás 
O. Amiano, Ruth Slimovich, Paulo C. Maffía, Eduardo Abbate, Rosa M. Musella, 
Verónica E. Garcia*, H. Eduardo Chuluyan*. Secretory leukocyte protease inhibitor: a new 
secreted pattern-recognition receptor for Mycobacteria. * Igual contribución al trabajo. Am 
J Respir Crit Care Med. 2009 ;179(3):247-53. ISSN: 1073-449X 
8. Virginia Pasquinelli; James C Townsend; Javier O Jurado; Ivana B Alvarez; María F 
Quiroga; Peter F Barnes; Buka Samten; Verónica García. IFN-γ production during active 
tuberculosis is regulated by mechanisms that involve IL-17, SLAM and CREB”. Journal of 
Infectious Diseases. 2009;199(5):661-5.
Publicaciones en revistas nacionales
9. “Contribución de la respuesta inmune del huésped al control de la infección por 
Mycobacterium tuberculosis”. Revista Química viva. Revista Electrónica del Depto. de 
Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos 
Aires, Argentina. Volumen 7. Número 2. Agosto 2008.
Capítulos de libros
17
10. Verónica García, Virginia Pasquinelli, Javier Jurado, Ivana Alvarez, Darío Fernández 
Do Porto. En edición. 2010Fainboim- Geffner. Introducción a la Inmunología Humana. 
6ta edición. Capítulo Inmunidad antibacteriana. 
Cáncer de próstata: modulación génica e inmunología (Gabriel Rabinovich)
a.i.1. GALECTIN-1 SUPPRESSES AUTOIMMUNE RETINAL INFLAMMATION BY 
PROMOTING CONCOMITANT T HELPER-2- AND T REGULATORY--MEDIATED 
ANTI-INFLAMMATORY RESPONSES. Marta A. Toscano, Alessandra Commadoro, Juan 
Ilarregui, Germán Bianco, Ana Liberman, Horacio M. Serra, Jun Hirabayashi, Luis V. 
Rizzo, Gabriel Rabinovich, Journal of Immunology, (2006) 176 (10)6323-6332.
a.i.2. SYNTHETIC LACTULOSE AMINES: NOVEL CLASS OF ANTICANCER 
AGENTS THAT INDUCE TUMOR-CELL APOPTOSIS AND INHIBIT GALECTIN-
MEDIATED HOMOTYPIC CELL AGGREGATION AND ENDOTHELIAL CELL 
MORPHOGENESIS. Gabriel Rabinovich, Albana Cumashi, Germán A. Bianco, Domenico 
Ciavardelli, Ida Iurisci, Maurizia D´Egidio, Enza Piccolo, Nicola Tinari, Nikolay Nifantiev, 
and Stefano Iacobelli. Glycobiology, (2006) 16: 210-220.
a.i.3. OVEREXPRESSION OF INDUCIBLE NITRIC OXIDE SYNTHASE AND 
CYCLOOXYGENASE- 2 IN RAT ZINC-DEFICIENT LUNG: INVOLVEMENT OF A 
NFκB- DEPENDENT PATHWAY. Nidia N. Gomez, Roberto C. Davicino, Veronica S. 
Biaggio, German A. Bianco, Silvina M. Alvarez, Patricia Fischer Lucas Masnatta, Gabriel 
A. Rabinovich, and María S. Gimenez. Nitric oxide, (2006) 14; 30-38. 
a.i.4. CIRCULATING ANTI-GALECTIN-1 AUTOANTIBODIES ARE ASSOCIATED 
WITH THE SEVERITY OF OCULAR DISEASE IN AUTOIMMUNE AND 
INFECTIOUS UVEITIS. Marta Romero, Juan.C. Muiñio, Germán A. Bianco, Mercedes 
Ferrero, Claudio P. Juarez, José D. Luna and Gabriel Rabinovich. Investigative 
Ophthalmology & Visual Sciences (2006) 47: 1550-1556. Trabajo distinguido con una 
editorial “Inside IOVS” de la revista IOVS.
a.i.5. HOW DO PROTEIN-GLYCAN INTERACTIONS REGULATE T-CELL 
PHYSIOLOGY? Marta Toscano, Juan M. Ilarregui, Germán Bianco, Natalia Rubinstein, & 
Gabriel Rabinovich. Medicina (Buenos Aires) (2006) 2006;66:357-62.
a.i.6. IMPACT OF PROTEIN-GLYCAN INTERACTIONS IN THE REGULATION OF 
AUTOIMMUNE AND CHRONIC INFLAMMATORY DISORDERS. Germán Bianco, 
Juan M. Ilarregui, Marta A. Toscano, Gabriel Rabinovich, Autoimmunity Reviews . (2006) 
5: 349-356.
a.i.7. LOW DOSES CYCLOPHOSPHAMIDE MODULATES EXPRESSION AND 
FUNCTION OF GALECTIN-1 IN AN EXPERIMENTAL LYMPHOMA MODEL. 
Mariano Zacarías, María J. Rico, Silvia I. Gervasoni, Juan M. Ilarregui, Marta Toscano, 
18
Gabriel Rabinovich, Graciela Scharovsky. Cancer Immunoloogy and Immunotherapy. 
(2007) 56(2):237-48.
a.i.8. FROM IMMUNE SURVEILLANCE TO TUMOR IMMUNE ESCAPE: STORY OF 
AN ENEMY WITH MULTIPLE COUNTERATTACK STRATEGIES. Graciela 
Scharovsky, Pablo Matar, Mariano Zacarías, María J. Rico, and Gabriel A. Rabinovich. 
Invitado por la revista Inmunología (España) (2006) 2006; 25(2)101-114.
a.i.9. ROLE OF GALECTINS IN CHRONIC INFLAMMATORY 
MICROENVIRONMENTS.Greg Parsonage, Emily Trebilcolck, Marta Toscano, Germán 
Bianco, Juan Ilarregui, Christopher Buckley, Gabriel Rabinovich. Future Rheumatology. 
(2006) 1(4) 441-454.
a.i.10. IMMUNOSUPPRESSIVE STRATEGIES THAT ARE MEDIATED BY TUMOR 
CELLS. Gabriel A. Rabinovich, Dmitry Gabrilovich and Eduardo Sotomayor. Annual 
Reviews Immunology. (2007) 25: 267-96. 
a.i.11. A NOVEL FUNCTION FOR GALECTIN-1 AT THE CROSSROAD OF INNATE 
AND ADAPTIVE IMMUNITY: GALECTIN-1 REGULATES MONOCYTE/ 
MACROPHAGE PHYSIOLOGY THROUGH A NON-APOPTOTIC ERK-DEPENDENT 
PATHWAY. Paula Barrionuevo, Macarena Beiger-Bompadre, Juan M Ilarregui, Marta 
Toscano, Germán Bianco, Martín Isturiz, Gabriel Rabinovich. Journal of Immunology, 
2007 178: 436-445.
a.i.12. TGF-β1 REGULATES GALECTIN-1 EXPRESSION IN METASTATIC 
MAMMARY ADENOCARCINOMA CELLS: IMPLICATIONS FOR TUMOR-IMMUNE 
ESCAPE. M. Cecilia Daroqui, Juan M. Ilarregui, Natalia Rubinstein, Mariana Salatino, 
Marta Toscano, Paula Vazquez, Lidia Puricelli, Elisa Bal de Kier-Joffe, Gabriel 
Rabinovich,Cancer Immunology and Immunotherapy, 2007 Apr;56(4):491-9. 
a.i.13. ALTERED EXPRESSION OF GALECTIN-3 INDUCES CORTICAL 
THYMOCYTE DEPLETION AND PREMATURE EXIT OF IMMATURE 
THYMOCYTES DURING TRYPANOSOMA CRUZI INFECTION. Elizangela Silva-
Monteiro, Luciana Reis-Lorenzato, Oscar Kenji-Nihei, Mara Junqueira, Gabriel A. 
Rabinovich, Dan Hsu, Fu-Tong Liu, Wilson Savino,Roger Chammas, Dea M. Serra Villa-
Verde. American Journal of Pathology, 2007;170:546-556.
a.i.14. COMPARATIVE STUDY OF THE ANTIINFLAMMATORY, ANTICOAGULANT 
AND ANTIANGIOGENIC ACTIVITIES OF SELECTED FUCOIDANS ISOLATED 
FROM BROWN SEAWEEDS. Albana Cumashi, Natalia A. Ushakova, Marina E. 
Preobrazhenskaya, Armida D’Incecco, Antonio Piccoli, Licia Totani, Nicola Tinari, Galina 
E. Morozevich, Albert E. Berman, Maria I. Bilan, Anatolii I. Usov, Nadezhda E. 
Ustuzhanina, Craig J. Sanderson, Maeve Kelly, Gabriel Rabinovich, Stefano Iacobelli, and 
Nikolay E. Nifantiev. Glycobiology, 2007, 2007 May;17(5):541-52.
a.i.15. DISSECTING THE PATHOPHYSIOLOGIC ROLE OF ENDOGENOUS 
LECTINS: GLYCAN-BINDING PROTEINS WITH CYTOKINE-LIKE ACTIVITY? 
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Marta A. Toscano, Juan M. Ilarregui, Germán Bianco, Diego Croci Russo, Leonardo 
Campagna, , Mariana Salatino, Gabriel Rabinovich. Cytokines and Growth Factors 
Reviews 2007; 18, 57-71.
a.i.16. CYTOKINES COMING OF AGE IN SOUTH AMERICA. Gabriel Rabinovich. 
Cytokines and Growth Factors Reviews 2007; 18, 1-3. 
a.i.17. GALECTINS: MATRICELLULAR GLYCAN-BINDING PROTEINS LINKING 
CELL ADHESION, MIGRATION AND SURVIVAL. Maria T. Elola, Carlota W. Todel, 
Gerardo Vasta, Gabriel Rabinovich. Cellular and Molecular Life Sciences 2007 ;64:1670-
700.
a.i.18. DYNAMIC CROSS-TALK BETWEEN TUMORS AND IMMUNE CELLS IN 
ORCHESTRATING THE IMMUNOSUPPRESSIVE NETWORK AT THE TUMOR 
MICROENVIRONMENT. Diego O. Croci, Mariano Zacarías Fluck, María J. Rico, Pablo 
Matar, Gabriel A. Rabinovich, and O. Graciela Scharovsky. Cancer Immunology & 
Immunotherapy (2007) 56:1687-700.
a.i.19. DIFFERENTIAL GLYCOSYLATION OF TH1, TH2 AND TH17 EFFECTOR 
CELLS SELECTIVELY REGULATES SUSCEPTIBILITY TO CELL DEATH. Marta A. 
Toscano, Germán A. Bianco, Juan M. Ilarregui, Diego Croci, Jorge Correale, Joseph 
Hernandez, Norberto W. Zwirner, Francoise Poirier, Eleanor Riley, Linda G. Baum, Gabriel 
A. Rabinovich. Nature Immunology(2007) 8(8) 825 – 834. a) Distinguido como feature 
article por Nature (www.nature.com). Mes de julio 2007. b) Destacado en la Sección 
“Research Highlights”(Nature Reviews Immunology 2007;7, 579. c)Distinguido en el sitio 
“Faculty of 1000 biology” como “Must Read”. Top 10 articles. d) Distinguido como 
ARTICULO DEL MES (agosto 2007) en Nature Glycomics (www.nature.com/glycomics). 
e) Distinguido en el TOP 10 del sitio de Nature Immunology (Septiembre 2007).
a.i.20. AN EMERGING ROLE FOR GALECTINS IN TUNING THE IMMUNE 
RESPONSE: LESSONS FROM EXPERIMENTAL MODELS OF INFLAMMATORY 
DISEASE, AUTOIMMUNITY AND CANCER. G. A. Rabinovich, F.T. Liu, M. Hirashima, 
A. Anderson. Scandinavian Journal of Immunology 2007; 66143-158.
a.i.21. TOLERANCE SIGNALING MOLECULES AND PREGNANCY: IDO, 
GALECTINS AND THE RENAISSANCE OF REGULATORY T CELLS. P. Terness, A. 
Mellor, G. Chaouat, G. Rabinovich, A. Betz, S. Saito, D. Clarck. American Journal of 
Reproductive Immunology. 2007;58:238-54.
a.i.22. NEURO-ENDOCRINE-IMMUNE DISEQUILIBRIUM AND ENDOMETRIOSIS: 
AN INTERDISCIPLINARY APPROACH Nadja Tariverdian Theoharis C. Theoharides, 
Friederike Siedentopf, Gabriela Gutiérrez, Udo Jeschke, Gabriel A. Rabinovich, Sandra M. 
Blois and Petra C. Arck Seminars in Immunopathology 2007; 29(2) 193-210.
a.i.23. Galectin-1 expression in human glioma cells: modulation by ionizing radiation and 
effects on tumor cell proliferation and migration. Herwig M. Strik, Katharina Schmidt, Paul 
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http://www.nature.com/glycomics
http://www.nature.com/
Lingor, Lars Tonges, Wilfried Kugler, Mirko Nitsche, Gabriel A. Rabinovich, Mathias Bähr. 
Oncology Reports, 18:483-488.
a.i.24. THE AP1-DEPENDENT SECRETION OF GALECTIN-1 BY REED-
STERNBERG CELLS FOSTERS IMMUNE PRIVILEGE IN CLASSICAL HODGKIN 
LYMPHOMA . Przemyslaw Juszczynski, Jing Ouyang, Jeffery Kutok, Stefano Monti, Wen 
Chen, Paola Dal Cin, Jeremy Abramson, Kunihiko Takeyama, Todd Golub, Jon Aster, 
Gabriel Rabinovich, Margaret Shipp. Proceedings of the National Academy of Science 
USA. (2007) 104: 13134-13139 (Agosto 1 early online publication).
a.i.25. INTEGRATING THE UNIVERSE OF REGULATORY CELLS IN CANCER: A 
MAJOR HURDLE FOR SUCCESSFUL IMMUNOTHERAPY. J. M. Ilarregui, D.O. Croci, 
M. Salatino, G.A. Bianco, M.A. Toscano and G.A. Rabinovich. Medicina (B Aires)- 
2007;67:25-31.
a.i.26. GALECTIN-CARBOHYDRATE LATTICES DURING INNATE AND ADAPTIVE 
IMMUNE RESPONSES. Gabriel Rabinovich, Marta Toscano, Gerardo Vasta. Current 
Opinion Structural Biology 2007 17(5):513-520. 
a.i.27. A PIVOTAL ROLE FOR GALECTIN-1 IN FETO-MATERNAL TOLERANCE. 
Sandra M. Blois, Juan M. Ilarregui, Mareike Tometten, Mariana García, Arif Suphi Orsal, 
Rosalia Cordo-Russo, Marta A Toscano, Germán Bianco, Bori Handjiski, Irene Tirado, Udo 
R. Markert, Francoise Poirier, Julia Szekeres-Bartho, Petra C Arck, Gabriel Rabinovich. 
Nature Medicine. (2007) 13:1450-1457.a) Distinguido como FEATURE ARTICLE en el 
area de Inmunología (Diciembre 2007) por Nature (www.nature.com). b) Distinguido con 
un RESEARCH HIGHLIGHT de Nature Reviews Immunology (mes de Enero 2008) 
(www.nature.com/nri). c) Distinguido en Nature Functional Glycomics como ARTICULO 
DEL MES (www.nature.com/glycomics). 
a.i.28. GALECTINS AS THERAPEUTIC TARGETS IN INFLAMMATORY DISEASES 
AND CANCER. Mariana Salatino, Diego Croci, Germán Bianco, Juan Ilarregui, Marta 
Toscano, Gabriel Rabinovich. Expert Opinion Biological Therapies. 2008 8(1):45-57.
a.i.29. CONTROL OF DENDRITIC CELL MATURATION AND FUNCTION BY 
TRIIODOTHYRONINE (T3). Iván Mascanfroni, S. Susperreguy, Juan M. Ilarregui, Susana 
Montesinos, Laura Cervi, Ana Repiso, Hector Targovnik, Gabriel Rabinovich, Claudia 
Pellizas. FASEB Journal. (2008); 22:1032-1042.
a.i.30. CRITICAL ROLE OF GALECTIN-1 IN THE CONTROL OF PLATELET 
ACTIVATION. Natalia Pacienza, Roberto G Pozner , Germán A. Bianco, Lina Paola 
D'Atri, Diego O. Croci, Soledad Negrotto, Elisa Malaver, Ricardo M. Gómez, Mirta 
Schattner, Gabriel A. Rabinovich. FASEB Journal (2008) 22: 1113-1123. TRABAJO 
DISTINGUIDO POR 1000 FACULTY BIOLOGY (Junio 2008). 
a.i.31. GALECTINS: STRUCTURE, FUNCTION AND THERAPEUTIC POTENTIAL. 
Ri-Yao Yang, Gabriel A. Rabinovich, and Fu-Tong Liu. Expert Reviews Molecular 
Medicine (2008) 10 doi: 10.1017/S1462399408000719. 
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http://www.nature.com/glycomics
http://www.nature.com/nri
http://www.nature.com/
a.i.32. INTRACELLULAR RETENTION OF MICA IN MELANOMAS PREVENTS 
RECOGNITION BY NK CELLS: NOVEL TUMOR IMMUNE ESCAPE MECHANISM. 
Mercedes B Fuertes, Luciana L Molinero, María V Girart, Carolina Domaica, Marcela 
Barrio, José Mordoh, Gabriel A Rabinovich and Norberto W Zwirner. Journal of 
Immunology- 2008; 180:4606-4614.
a.i.33. APOPTOSIS RESISTANCE IN HIV-1 PERSISTENTLY-INFECTED CELLS IS 
INDEPENDENT OF ACTIVE VIRAL REPLICATION AND INVOLVES MODULATION 
OF THE APOPTOTIC MITOCHONDRIAL PATHWAY. Pablo Nicolás Fernández Larrosa, 
Diego Croci, Diego Riva, Mariel Bibini, Renata Luzzi, Mónica Saracco, Susana Mersich, 
Gabriel A. Rabinovich, Liliana Martínez Peralta. Retrovirology (2008), 
5:19doi:10.1186/1742-4690-5-19. http://www.retrovirology.com/content/5/1/19. 
a.i.34. AP-1-DEPENDENT GALECTIN-1 EXPRESSION DELINEATES CLASSICAL 
HODGKIN AND ANAPLASTIC LARGE CELL LYMPHOMAS FROM OTHER 
TUMORS WITH SHARED MOLECULAR FEATURES. Scott J. Rodig, Jing Ouyang, 
Przemyslaw Juszczynski, Treeve Currie, Kenneth Law, Donna S. Neuberg, Gabriel A. 
Rabinovich, Margaret A. Shipp and Jeffery L. Kutok. Clinical Cancer Research (2008) 14: 
3338-3344.
a.i.35. PROTEIN-GLYCAN INTERACTIONS IN THE CONTROL OF INNATE AND 
ADAPTIVE IMMUNE RESPONSES. Yvette van Kooyk and Gabriel A. Rabinovich. 
Nature Immunology, (2008)9,593-601.
a.i.36. SILENCING SURVIVIN GENE EXPRESSION INHIBITS PROLIFERATION 
AND PROMOTES APOPTOSIS OF BREAST CANCER CELLS BY A CASPASE-
INDEPENDENT PATHWAY. Diego O. Croci, Ingrid S. Cogno, Natalia B. Rumie Vittar, 
Edgardo Salvatierra, Osvaldo L. Podhajcer, Eduardo Osinaga, Viviana A. Rivarola, 
Gabriel Rabinovich. Journal of Cellular Biochemistry 2008; 105: 2:381-390.
a.i.37. IMMUNOLOGY SOUTH OF THE EQUATORIN THE AMERICAS. Gabriel A. 
Rabinovich, Alexis Kalergis, Norberto W. Zwirner, Wilson Savino. Nature Immunology, 
2008, 9(10):1087-1090.
a.i.38. CRITICAL ROLE OF THE SOLVENT ENVIRONMENT IN GALECTIN-1 
BINDING TO ITS SPECIFIC DISACCHARIDE LACTOSE. Santiago Di Lella, Lu Ma, 
Juan C. Diaz-Ricci, Gabriel A. Rabinovich, Sanford A. Asher, and R. Maria S. Alvarez. 
Biochemistry, (2009) 48(4):786-91.
a.i.39. SYNTHETIC INHIBITORS OF GALECTINS-1 AND -3 SELECTIVELY 
MODULATE DIFFERENT STEPS OF TUMOR PROGRESSION. Ida Iurisci , Albana 
Cumashi, , Andrei A. Sherman, Nicola Tinari, Enza Piccolo, Maurizia D’Egidio, Yury E. 
Tsvetkov, Gabriel A. Rabinovich, Nikolay E. Nifantiev Stefano Iacobelli. Anticancer 
Research, 2009, 29:1 403-410.
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http://www.retrovirology.com/content/5/1/19
a.i.40. DUODENAL INTRAEPITHELIAL INTESTINAL LYMPHOCYTES FROM 
FOOD ALLERGY PATIENTS SELECTIVELY BIND THE GLYCAN-BINDING 
PROTEIN GALECTIN-3. Natalia Mercer, Ricardo Drut, Cueto Rua, Liliana Guzman, 
Marta Toscano, Gabriel Rabinovich, Guillemo H Docena International Journal of 
Immunopathology and Pharmacology, 2009 22(1):207-217.
a.i.41. TURNING ‘SWEET’ ON IMMUNITY: GALECTIN-GLYCAN INTERACTIONS 
IN IMMUNE TOLERANCE AND INFLAMMATION. Gabriel A. Rabinovich and Marta A 
Toscano. Nature Reviews Immunology, 2009; 9(5): 338-352.
a.i.42. GALECTIN-3 INDUCES A DISTINCTIVE PATTERN OF CYTOKINE AND 
CHEMOKINE PRODUCTION IN RHEUMATOID SYNOVIAL FIBROBLASTS VIA 
SELECITVE SIGNALLING PATHWAYS. Andrew D. Filer, Magdalena Bik, Greg N. 
Parsonage, John Fitton, Emily Trebilcock, Katherine Howlett, Karin Raza, David L. 
Simons, Mike Salmon, Dagmar Scheel-Toellner, Janet M. Lord, Gabriel A. Rabinovich, 
Christopher D. Buckley. Arthritis & Rheumatism 2009 60(6):1604-1614.
a.i.43. GUIDELINES FOR THE USE AND INTERPRETATION OF ASSAYS FOR 
MONITORING CELL DEATH IN HIGHER EUKARYOTES. Lorenzo Galluzzi, John 
Abrams, Emad S. Alnemri, Eric H. Baehrecke, Mikhail V. Blagosklonny, Catherine 
Brenner, Maria Castedo, Ruggero de Maria, Wafik S. El-Deiry, Simone Fulda, Carmen 
Garrido, Pierre Golstein, Douglas R. Green, Hinrich Gronemeyer, Michael Hengartner, 
Marja Jäättelä, Oliver Kepp, Daniel J. Klionsky, Richard A. Knight, Sally Kornbluth, Peter 
H. Krammer, Sharad Kumar, Stuart A. Lipton, Frank Madeo, Walter Malorni, Patrick 
Mehlen, Gerry Melino, Eugenia Morselli, Pierluigi Nicotera, Gabriel Nuñez, Josef 
Penninger, Marcus E. Peter, Mauro Piacentini, Gabriel A. Rabinovich, Guy S. Salvesen, 
Luca Scorrano, Hans-Uwe Simon, Andreas Strasser, Jürg Tschopp, Peter Vandenabeele, 
Andreas Villunger, Junying Yuan, Boris Zhivotovsky and Guido Kroemer. Cell Death and 
Differentiation, 2009, 16(8):1093-107. 
a.i.44. TUMOR EXPERIENCED-ACTIVATED T CELLS MODULATE NKG2D- AND 
NKp46-DEPENDENT NK CELL FUNCTIONS THROUGH TROGOCYTOSIS OF 
SPECIFIC LIGANDS FROM THE TUMOR CELL SURFACE. Carolina I. Domaica, 
Mercedes Fuertes, Maria V. Girart, Lucas Rossi, Damián Avila, Gabriel Rabinovich and 
Norberto Zwirner. EMBO Reports (2009) 10: 908–915. 
a.i.45. CONVEYING GLYCAN-CONTAINING INFORMATION INTO T-CELL 
HOMEOSTATIC PROGRAMS: A CHALLENGING ROLE OF GALECTIN-1 IN 
INFLAMMATORY AND TUMOR MICROENVIRONMENTS. G.A. Rabinovich and J.M. 
Ilarregui Immunological Reviews (2009) 230: 144-159.
a.i.46. EMERGING CONCEPTS IN TOLERANCE AND AUTOIMMUNITY: NOVEL 
THERAPEUTIC APPROACHES. Esteban Ciliberti, Leandro Carambia, Sebastian 
Cavallin, Osvaldo L. Cerda, Juan J. Poderoso and Gabriel A. Rabinovich. Medicina (B 
Aires) 2009; 69(4): 460-465.
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a.i.47. TOLEROGENIC SIGNALS DELIVERED BY DENDRITIC CELLS TO T CELLS 
VIA A GALECTIN-1-DRIVEN IMMUNOREGULATORY CIRCUIT INVOLVING IL-27- 
AND IL-10. Juan M. Ilarregui, Diego O. Croci, Germán A. Bianco, Marta Toscano, 
Mariana Salatino, Mónica Vermeulen, Jorge Geffner, Gabriel Rabinovich. Nature 
Immunology, (2009) 10(9): 981 – 991. Distinguido por 1000 Faculty Biology (sitio donde 
se destacan los mejores trabajos del año en cada área) como EXCEPCIONAL (Puntaje 9.0). 
Seleccionado entre los Top 10 Articles por Nature Immunology
a.i.48. Gérard A, Ghiotto M, Fos C, Guittard G, Compagno D, Galy A, Lemay S, Olive. D, 
Nunès JA. Dok-4 is a novel negative regulator of T cell activation.(2009) J Immunol, 
182(12):7681-7689.
Laboratorio de Estudios de estrés osmótico en bacterias Gram positivas (Carmen 
Sánchez/ Sandra Ruzal)
1. Palomino MM, Sanchez Rivas C and SM Ruzal. High salt stress in Bacillus subtilis: 
Involvement of PBP4* as a peptidoglycan hydrolase Research in Microbiology (2009) 
160:117-124
2. Prado-Acosta M, Palomino MM, Allievi MC, Sanchez Rivas C and SM Ruzal. The S-
layer of Lactobacillus acidophilus ATCC 4356 shows Murein Hydrolase Activity Applied 
and Environmental Microbiology (2008) 74:7824–7827
3. Lopez CS, Alice AF, Heras H, Rivas EA, Sanchez-Rivas C Role of anionic 
phospholipids in the adaptation of Bacillus subtilis to high salinity. Microbiology. (2006) 
152:605-16.
Genética y Ecología Microbianas (Beatriz Mendez/ Julia Pettinari)
1. Ayub, N. D.; Pettinari, M. J.; Méndez, BS and N. I. López. 2006.Impaired 
polyhydroxybutyrate biosynthesis from glucose in Pseudomonas sp. 14-3 is due to a 
defective beta-ketothiolase gene. FEMS Microbiology. Letters 264:125131.
2. Ruiz J. A, Fernández R. O, Nikel P.I, Méndez B.S & Pettinari M.J. 2006
dye (arc) mutants: insights into an unexplained phenotype and its suppression by the 
synthesis of poly (3-hydroxybutyrate) in Escherichia coli recombinants. FEMS Microbiol. 
Lett. 258: 55-60.
3. Nikel P.I, Pettinari M.J, Galvagno M.A and Méndez B.S. 2006. Poly(3 hydroxybutyric 
Acid) Synthesis by Recombinant Escherichia coli arcA mutants in microaerobiosis. Appl. 
Environ. Microbiol. 72: 2614-2620.
4. Nikel Pablo Iván, Alejandra de Almeida, Evelia Melillo, Miguel Ángel Galvagno and 
Ma. Julia Pettinari.(2006). New recombinant Escherichia coli strain tailored for the 
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production of poly(3-hydroxybutyrate) from agroindustrial by-products. Applied and 
Environmental Microbiology. 72: 3949-3954.
5. de Almeida Alejandra, Beatriz S. Méndez y M. Julia Pettinari (2006) Nuevas 
oportunidades para productos bacterianos. Revista Industria y Química. 354: 22-25
6. de Almeida Alejandra, Pablo I. Nikel, Andrea M. Giordano, and M. Julia
7. Pettinari (2007). Effects of Granule-Associated Protein PhaP on Glycerol-Dependent 
Growth and Polymer Production in Poly(3-Hydroxybutyrate)-Producing Escherichia coli. 
Applied and Environmental Microbiology. 73: 7912-7916.
8. Ayub, N.D., Pettinari, M.J. , Méndez B.S. & N.I. López. 2007. The 
polyhydroxyalkanoate genes of a stress resistant Antarctic Pseudomonas are situated within 
a genomic island. Plasmid 58:240-248.
9. Pettinari, M.J., Nikel. P.I., Ruiz, J.A. and Méndez, B. S. 2008. ArcA redox mutants as a 
source of reduced bioproducts. J. Molec. Microbiol. Biotechnol. 15: 41-47. (review upon 
invitation by the editors).
10. Nikel. P.I., Pettinari, M.J., Ramírez, C., Galvagno, M. A. and Méndez,
B. S. 2008. Escherichia coli arcA mutants: metabolic profile characterization of 
microaerobic cultures using glycerol as a carbon source. J. Molec. Microbiol. Biotechnol. 
15: 48-54. 
11. Nikel P.I., Pettinari, M.J., Galvagno, M. A. and Méndez B. S. 2008. Poly(3-
hydroxybutyrate) synthesis from glycerol by a recombinant Escherichia coli arcA mutant in 
fed-batch microaerobic cultures Appl. Microbiol. Biotechnol, 77: 1337-1343. 
12. Nikel. P.I., de Almeida A, Pettinari, M.J. and Méndez B. S. 2008. The Legacy of HfrH: 
Mutations in the Two-Component System CreBC are responsible for the Unusual 
Phenotype of an Escherichia coli arcA Mutant. J.Bacteriol.190: 3004-3007.
13. Nikel. P.I,. Zhu J, San K-Y, Méndez, B. S, and Bennett, G.N. 2009. Metabolic Flux 
Analysis of Escherichia coli creB and arcA Mutants Reveals Shared Control of Carbon 
Catabolism under Microaerobic Growth Conditions. J. Bacteriol. 5538-5548. 
14. López, N.I., Pettinari, M.J., Stackebrandt, E., Tribelli, P.M.,Potter, M., Steinbüchel, A. 
and B.S. Méndez 2009. Pseudomonas extremaustralis sp.nov. a polyhydroxybutyrate-
producer isolated from Antarctic environments. Current Microbiology 59: 514-519.
Laboratorio de Biotecnología Ambiental y Ecología Bacteriana (Nancy Lopez)
1. Ayub, N.D., Tribelli,P.M. and N.I. López. 2009. Polyhydroxyalkanoates are essential 
for maintenance of redox state in the Antarctic bacterium Pseudomonas sp. 14-3 during 
low-temperature adaptation. Extremophiles, 13:59-66. 
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2. Raiger Iustman, L.J. y N.I. López. 2009. Los biosurfactantes y la industria petrolera. 
Revista Química Viva. Número 3, año 8, Diciembre . Revista electrónica del Departamento 
de Química Biológica. FCEyN. UBA. ISSN 1666-7948. www.quimicaviva.qb.fcen.uba.ar. 
Laboratorio de Fisiología celular de la Eritropoyetina (Alcira Nesse)
1. Pregi N, Wenker S, Vittori D, Perez Leiros C, Nesse A (2009). TNF-alpha-induced 
apoptosis is prevented by erythropoietin treatment on SH-SY5Y cells. Exp Cell Res 
315:419-431.
2. Pregi N, Vittori D, Perez G, Perez Leiros C, Nesse A. (2006) Effect of erythropoietin 
on staurosporine-induced apoptosis and differentiation of SH-SY5Y neuroblastoma cells. 
Biochim Biophys Acta 1763: 238-246.
3. Callero M, Pérez G, Vittori D, Pregi N, Nesse A. Modulation of tyrosine phosphatase 
1B by erythropoietin in UT-7 cell line. Cell Physiol Biochem 20:319-28, 2007. ISSN: 
1015–8987. 
4. Pérez G, Romero MC, Trigo P, Lendoire J, Imventarza O, Nesse A. Polineuropatía 
amiloidótica familiar tipo I. Diagnóstico en la Argentina. Medicina (Bs As) 68:273-81, 
2008. ISSN 0025-7680. 
5. Calafat M, Larocca L, Roca V, Hauk V, Pregi N, Nesse A, Pérez Leirós C. Vasoactive 
intestinal peptide inhibits TNF--induced apoptotic events in acinar cells from non obese 
diabetic mice submandibular glands. Arthritis Research & Therapy 11(2):1-10, 2009 
(http://arthritis-research.com/content/11/2/R53). ISSN 1478-6354. 
Laboratorio de Apoptosis en el Sistema Nervioso-Nanooncología (Mónica Kotler)
1. Magariños, M.P.; Sánchez-Margalet, V.; Kotler, M.L.; Calvo, J.C. & Varone, C.L. 
Leptin promotes cell proliferation and survival of trophoblastic cells Biol. Reprod. (2007) 
76 (2) 203-210.
2. Gonzalez, L.E., Juknat A.A., Venosa A., Verrengia N. & Kotler M.L Manganese 
activates the mitochondrial apoptotic pathway in rat astrocytes by modulating the 
expression of proteins of the Bcl-2 family Neurochem. Int. (2008) 53, 408-415.
3. Llansola Portolés, M.; Rodriguez Nieto, F.; Soria, D.; Amalvy, J.; Peruzzo, P.; Mártire, 
D.; Kotler, M.L.; Holub, O; Gonzalez, M. Photophysical properties of blue – emitting 
silicon nanoparticles The Journal of Physical Chemistry C (2009) 113 (31), 13694–13702.
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http://arthritis-research.com/content/11/2/R53
http://www.quimicaviva.qb.fcen.uba.ar/
Laboratorio de Apoptosis y Cáncer (Elba Vázquez/ Adriana De Siervi)
1. Gueron G, De Siervi A, Ferrando M, Salierno M, De Luca P, Elguero B, Meiss R, 
Navone N, Vazquez ES. Critical role of endogenous heme oxygenase 1 as a tuner of the 
invasive potential of prostate cancer cells. 2009 Mol Cancer Res. 7(11):1745-55.
2. Becher E., Toblli J., Castruonovo C., Nolazco C., Rosenfeld C., Grosman H., Vazquez 
E., Mazza O. Expression of caveolin-1 in penile cavernosal tissue in a denervated animal 
model after treatment with sidenafil citrate. 2009 J. Sex. Med. 6: 1587-93.
3. Li ZG, Mathew P, Yang J, Starbuck M, Zurita A, Liu J, Sikes Ch., Multani A, 
Efstathiou E, Lopez A, Wang J, Fanning T, Prieto V, Kundra V, Vazquez E, Troncoso P, 
Raymond R, Logothetis C, Lin S-W, Maity S, Navone N. Androgen Receptor–Negative 
Human Prostate Cancer Cells Induce Osteogenesis through FGF9- Mediated Mechanisms. 
2008 J. Clin. Invest. 118: 2697-2710.
4. Li ZG, Yang J, Vazquez ES, Rose D, Vakar-Lopez F, Mathew P, Lopez A, Logothetis 
CJ, Lin S-H & Navone NM. Low-density lipoprotein receptor-related protein 5 (LRP5) 
mediates the prostate cancer-induced formation of new bone 2008 Oncogene 27: 596-603
5. Sacca P., Meiss R., Casas G., Mazza O., Calvo JC., Navone N., Vazquez E. Nuclear 
translocation of heme oxygenase-1 is associated to prostate cancer. 2007 Br. J. Cancer 97: 
1683-9.
6. Castronuovo C., Sacca P., Meiss R., Caballero A., Batlle A. & Vazquez E. Homeostatic 
response under carcinogen withdrawal, heme oxygenase 1 expression and cell cycle 
association. 2006 BMC Cancer 6, 286-295.
7. Byun JS, Wong MM, Cui W, Idelman G, Li Q, De Siervi A, Bilke S, Haggerty CM, 
Player A, Wang YH, Thirman MJ, Kaberlein JJ, Petrovas C, Koup RA, Longo D, Ozato K, 
Gardner K. Dynamic bookmarking of primary response genes by p300 and RNA 
polymerase II complexes. Proc Natl Acad Sci USA. 106(46):19286-91 (2009).
8. De Siervi A, De Luca P, Moiola C, Gueron G, Tongbai R, Chandramouli GV, Haggerty 
C, Dzekunova I, Petersen D, Kawasaki E, Kil WJ, Camphausen K, Longo D, Gardner K. 
Identification of new Rel/NFkappaB regulatory networks by focused genome location 
analysis. Cell Cycle. 8(13):2093-100 (2009).
9. Macias E, Miliani de Marval PL, De Siervi A, Conti CJ, Senderowicz AM, Rodriguez-
Puebla ML. CDK2 activation in mouse epidermis induces keratinocyte proliferation but 
does not affect skin tumor development. Am J Pathol. 173(2):526-35 (2008).
10. Ge Y, Byun JS, De Luca P, Gueron G, Li QQ, Yabe IM, Sadiq-Ali SG, Figg WD, 
Quintero J, Haggerty CM, De Siervi A, Gardner K. Combinatorial anti-leukemic disruption 
of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 
CPS49 and flavopiridol. Mol Pharmacol. 74(3):872-83 (2008).
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http://www.ncbi.nlm.nih.gov/pubmed/19880750?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=3
Laboratorio de Biología tumoral (Rosa Wainstok)
1. Gazzaniga S., Bravo A.I., Mordoh J., Wainstok R. Monocyte chemoattractant protein 
correlates with angiogenesis in metastatic melanoma. Acta Bioquím Clin Latinoam 40, 463-
467; 2006
2. Gazzaniga S., Bravo A. I., Guglielmotti A., van Rooijen N., Maschi F.,Vecchi A., 
Mantovani A., Mordoh J., Wainstok R. Targeting Tumor-Associated Macrophages and 
Inhibition of MCP-1 Reduce Angiogenesis andTumor Growth in a Human Melanoma 
Xenograft. Journal of Investigative Dermatology 2007, 127(8):2031-41.
3. Von Euw E., Barrio M.M., Furman D., Bianchini M., Levy E.M., Yee C., Li Y., 
Wainstok R., Mordoh J. Monocyte- derived dendritic cells loaded with a mixture of 
apoptotic/necrotic melanoma cells efficiently cross-present gp100 and MART-1antigens to 
specific CD8+ T lymphocytes. Journal of Translational Medicine 2007, 5:19
4. Von Euw E., Barrio M.M., Furman D., Levy E.M., Bianchini M., Peguillet I., Lantz O., 
Vellice A., Kohan A., Chacón M., Yee C., Li Y., Wainstok R., Mordoh J.A fase I clinical 
study of vaccination of melanoma patients with dendritic cells loaded with allogenic 
apoptotic/ necrotic melanoma cells. Analysis of toxicity and immune response to the 
vaccine and of IL-10-1082 promoter genotype as predictor of disease progression. Journal 
of Translational Medicine 2008, 6: 6
Laboratorio de Hemostasia y Trombosis (Lucía Kordich)
1. Quintana IL , Oberholzer MV, Kordich L, Lauricella AM. Impaired fibrin gel 
permeability by high homocysteine levels. Thrombosis Research. 2009 Sep 9.ISSN 0049-
3848, DOI: 10.1016/j.thromres.2009.08.013.
2. Ana María Rojas, Lucía Kordich, Ana María Lauricella. Homocysteine modifies fibrin 
clot deformability. Another possible explanation of harm. Biorheology. 2009; 46(5): 379-
87.
3. Lauricella AM, De Panis DN, Arín A, Rosa G. Importancia de la estructura de la 
fibrina en su lisabilidad: Estudio en distintas situaciones patológicas” Hematológica (ISSN 
1138-0381) (ed. esp.). 2009, 94 (Extraordinario Nº 1) 428-432.
4. Trimarchi H , Duboscq C, Genoud V, Lombi F, Muryan A, Young P, Schwab M, 
Castanon M, Rodriguez-Reimundes E, Forrester M, Pereyra H, Campolo-Girard V, 
Seminario O, Alonso M, Kordich L. Plasminogen activator inhibitor-1 activity and 4G/5G 
polymorphism in hemodialysis. The Journal of Vasccular Access. 2008 Apr-Jun;9(2):142-
7.
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http://www.ncbi.nlm.nih.gov/pubmed/18609532?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=4
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5. Quintana I., Lauricella A., Castañon M., Genoud V., Sassetti B., Kordich L. Trombosis: 
Conocerla para evitarla. Revista Industria y Química. 2008; 357: 9-11.
6. Castañon MM, Gamba C, Kordich L. Insight into the profibrinolytic activity of 
dermatan sulfate: effects on the activation of plasminogen mediated by tissue-type and 
urinary-type plasminogen activator. Thrombosis Research 2007; 120, 745-752. 
7. Castañon MM, Lauricella AM, Kordich L, Quintana I. Plasma homocysteine cut-off 
values associated to venous thrombosis. Clinical Chemistry and Laboratory Medicine 2007; 
45 (2): 232-6. 
8. Lauricella AM. Variabilidad de las Redes de Fibrina. Acta Bioquímica Clínica 
Latinoamericana (ISSN 0325- 2957) 2007; 41 (1): 7- 19. 
9. Ciancia M, Quintana I, Vizcargüénaga MI, Kasulin L, De Dios A, Estevez J Cerezo A. 
Polysaccharides from the green seaweed Codium fragile and C. vermilara with 
controversial effects on hemostasis. Internacional Journal of Biological Macromolecules 
(ISSN 0141- 8130) 2007; 41 (5): 641- 649. 
10. Lauricella A, Quintana I, Castañon M, Sassetti B, Kordich L. Influence of 
Homocysteine on fibrin network lysis. Blood Coagulation and Fibrinolysis 2006, 17: 181-
186
11. Castañon M., Lauricella AM., Genoud V., Quintana I. Importancia de la Determinación 
de Homocisteinemia y MTHF Reductasa. Acta Bioquímica Clínica Latinoamericana (ISSN 
0325- 2957) 2006; 40 (3): 335-339.
12. Ana María Lauricella. La Homocisteína Modifica las Redes de Fibrina. Revista 
Química Viva. Diciembre 2006, vol. 5, Número 003, pp. 56-72. Universidad de Buenos 
Aires.
13. Ciancia M, Quintana I, Vizcargüénaga MI, , Kasulin L, De Dios A, Estevez J Cerezo A. 
Polysaccharides from the green seaweed Codium fragile and C. vermilara with 
controversial effects on hemostasis. Internacional Journal of Biological Macromolecules 
(ISSN 0141- 8130) 2007; 41 (5): 641- 649.
Laboratorio de Inmunofarmacología (Claudia Perez Leirós)
1. Roca V, Calafat M, Larocca L, Ramhorst R, Farina M, Franchi AM, Perez Leiros C 
(2009). Potential immunomodulatory role of VIP in the implantation sites of prediabetic 
nonobese diabetic mice. Reproduction 138:733-742.
2. Fraccaroli L, Alfieri J, Leiros CP, Ramhorst R (2009). Immunomodulatory effects of 
chemokines during the early implantation window. Front Biosci (Elite Ed). 1:288-298.
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3. Calafat M, Larocca L, Roca V, Hauk V, Pregi N, Nesse, A, Perez Leiros C (2009). 
Vasoactive intestinal peptide inhibits TNF-¦Á-induced apoptotic events in acinar cells from 
nonobese diabetic mice (NOD) submandibular glands. Arthritis Res Ther. 11:R53 (pp1-10).
4. Fraccaroli L, Alfieri J, Larocca L, Calafat M, Roca V, Lombardi E, Ramhorst R, Perez 
Leiros C (2009). VIP modulates the pro-inflammatory maternal response inducing tolerance 
to trophoblast-cells. Br J Pharmacol 156:116-126
5. Fraccaroli L, Alfieri J, Larocca L, Calafat M, Mor Gil, Perez Leiros C, Ramhorst R. 
(2009) A potential tolerogenic immune mechanism by trophoblast cells through the 
activation of chemokine-induced T cell death and regulatory T cell modulation. Human 
Reproduction 24:166-175.
6. Larocca L, Ramhorst R, Roca V, Calafat M, Aisemberg J, Franchi A, Perez Leiros C 
(2008). Neuroimmune-endocrine interactions during early pregnancy in an autoimmune 
context: focus on macrophage activation. Neuroimmunomodulation 15:84-90.
7. Calafat M, Larocca L, Roca V, Perez Leiros C (2007). NOD mice exocrinopathy: 
towards a neuroimmune link. Neuroimmunomodulation. 14:175-181.
8. Larocca L., Calafat M, Roca V, Franchi, A, Perez Leiros C (2007). VIP limits LPS-
induced nitric oxide production through IL-10 in NOD mice macrophages. Int. 
Immunopharmacol. 7:1343-1349.
9. Roca V, Larocca L, Calafat M, Aisemberg J, Meiss R, Franchi AM, Perez Leiros C 
(2006). Reduced nitric oxide synthase and cyclo-oxygenase activity in the uterus of NOD 
mice. Reproduction 132: 931-938, 2006.
10. Rosignoli F, Torroba M, Juarranz Y, Garcia Gomez M, Martinez C, Gomariz RP, Perez 
Leiros C, Leceta J (2006). VIP tolerante induction in autoimmunity. Ann N Y Acad Sci 
USA 1070:525-530.
Laboratorio de Metabolismo del hemo: Porfirias y enfermedades relacionadas 
(Victoria Parera/ María Victoria Rossetti)
1. Lavandera, J.; Parera, V.; Batlle, A. & Buzaleh, A.M. CYP2D6 polymorphisms in 
patients with porphyrias. Mol. Med. 12 (9-10) (2006):259-263.
2. Lavandera, J.; Batlle, A. & Buzaleh, A.M. Metabolization of porphyrinogenic agents in 
brain: involvement of the Phase I drug metabolizing system. A comparative study in liver 
and kidney Cell. Mol. Neurobiol. 27 (2007) 717-729
3. Buzaleh, A.M.; Morán-Jiménez, M.J.; García-Bravo, M.; Sampedro, A.; Batlle A., 
Enríquez de Salamanca R. & Fontanellas, A. Induction of Hepatic Aminolevulinate Acid 
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Synthetase Activity by Isoflurane in a Genetic Model for Erythropoietic Protoporphyria. 
Cell. Mol. Biol 55 (1) (2009), 38-44
4. Lavandera, J.; Fossatti, M.; Azcurra,