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Development of blood in adults Klaus O. Kaefer 7th 1 Components of blood tissue: Plasma (water, ions, organic molecule, vitamins, gases) and cells (red blood cells, white blood cells, platelets) 2 All cells are production from Blood stem cell, this cell is formed in the red bone marrow. 3 Slides de Exemplo After blood stem divided in Myeloid stem cell and lymphoid stem cell. 4 Slides de Exemplo Myeloid stem cell form: red blood cells (5.106 for ml/blood) and platelets (150-450.103 for ml/blood) and myeloblast (form one type white blood cells) Lymphoid stem cells form: Lymphoblast and it form other white blood cells(4-11.103 for ml/blood) 5 Erythrocyte (main function is transport O2 from lung to cells by circulator system, don´t have a nucleus) is need 7 days to form in red bone marrow, need stimulation from hormone that called Erythropoietin, this hormone is formed in kidney (85%) or liver (15%) when pressure O2 is minor than 60mmHg (hypoxia) 6 White cell (main function is defence and immunity of the organism, have a nucleus) formed by Lymphoid stem cell and Myeloblast, divided in 5 type cells: Neutrophils(62%), Lymphocytes (30%), Monocytes (5%), Eosinophil (2,5%) and Basophils(0,75%). 7 Platelets (main function is haemostasis and clotting) form from fragmentation of Megakaryocytes. 8
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