What Is the Treatment for Candida Infection of Implantable Cardiac Devices? 65. For pacemaker and implantable cardiac defibrillator infections, t...

What Is the Treatment for Candida Infection of Implantable Cardiac Devices?


65. For pacemaker and implantable cardiac defibrillator infections, the entire device should be removed (strong recommendation; moderate-quality evidence).
66. Antifungal therapy is the same as that recommended for native valve endocarditis (strong recommendation; low-quality evidence).
67. For infections limited to generator pockets, 4 weeks of antifungal therapy after removal of the device is recommended (strong recommendation; low-quality evidence).
68. For infections involving the wires, at least 6 weeks of antifungal therapy after wire removal is recommended (strong recommendation; low-quality evidence).
69. For ventricular assist devices that cannot be removed, the antifungal regimen is the same as that recommended for native valve endocarditis (strong recommendation; low-quality evidence). Chronic suppressive therapy with fluconazole if the isolate is susceptible, for as long as the device remains in place is recommended (strong recommendation; low-quality evidence).