What is the recommended treatment for Leishmaniasis Mucosa? I - The treatment of LM should preferably be carried out in reference centers with oto...
What is the recommended treatment for Leishmaniasis Mucosa?
I - The treatment of LM should preferably be carried out in reference centers with otorhinolaryngological evaluation.
II - The first choice for treatment is pentamidine isethionate for all patients except those with renal, hepatic or cardiac comorbidity, diabetics, pregnant or lactating women.
III - The second choice for treatment is meglumine antimoniate, followed by deoxycholate amphotericin B and liposomal amphotericin B.
IV - The recommended dose of meglumine antimoniate is 20 mg Sb+5/kg/day for 30 consecutive days.
V - The use of pentoxifylline is contraindicated in pediatric patients.
a) I, II, III and IV are correct.
b) I, III and IV are correct.
c) II, III and V are correct.
d) I, II, IV and V are correct.
I - The treatment of LM should preferably be carried out in reference centers with otorhinolaryngological evaluation.
II - The first choice for treatment is pentamidine isethionate for all patients except those with renal, hepatic or cardiac comorbidity, diabetics, pregnant or lactating women.
III - The second choice for treatment is meglumine antimoniate, followed by deoxycholate amphotericin B and liposomal amphotericin B.
IV - The recommended dose of meglumine antimoniate is 20 mg Sb+5/kg/day for 30 consecutive days.
V - The use of pentoxifylline is contraindicated in pediatric patients.
a) I, II, III and IV are correct.
b) I, III and IV are correct.
c) II, III and V are correct.
d) I, II, IV and V are correct.
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Ed 
A leishmaniose mucosa é uma forma de leishmaniose que afeta principalmente as mucosas do nariz, boca e garganta. O tratamento recomendado para a leishmaniose mucosa é o uso de medicamentos antileishmania, como o antimoniato de meglumina, anfotericina B desoxicolato e anfotericina B lipossomal. A pentamidina isetionato também pode ser usada, mas é menos eficaz e deve ser evitada em pacientes com comorbidades renais, hepáticas ou cardíacas, diabéticos, grávidas ou lactantes. A dose recomendada de antimoniato de meglumina é de 20 mg Sb+5/kg/dia por 30 dias consecutivos. Portanto, a alternativa correta é a letra b) I, III e IV estão corretas.
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