What is the effect of tissue infection on local anesthesia? I. Infected tissues tend to be more acidic, reducing the proportion of non-ionized dru...
What is the effect of tissue infection on local anesthesia?
I. Infected tissues tend to be more acidic, reducing the proportion of non-ionized drug and slowing down the onset of action.
II. Infected tissues may have a higher local blood flow, leading to greater removal of the local anesthetic before it can act on neurons.
III. Infected tissues may have a higher concentration of PABA, which can cause allergic reactions to ester-type local anesthetics.
IV. Infected tissues may have a higher concentration of adrenaline, which can increase the absorption of local anesthetics.
a. I and II only
b. II and III only
c. I, II, and III only
I. Infected tissues tend to be more acidic, reducing the proportion of non-ionized drug and slowing down the onset of action.
II. Infected tissues may have a higher local blood flow, leading to greater removal of the local anesthetic before it can act on neurons.
III. Infected tissues may have a higher concentration of PABA, which can cause allergic reactions to ester-type local anesthetics.
IV. Infected tissues may have a higher concentration of adrenaline, which can increase the absorption of local anesthetics.
a. I and II only
b. II and III only
c. I, II, and III only
💡 1 Resposta
Ed 
O efeito da infecção tecidual na anestesia local é que os tecidos infectados tendem a ser mais ácidos, reduzindo a proporção de droga não ionizada e retardando o início da ação. Portanto, a alternativa correta é a letra "a" - I e II apenas.
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