What factors influence drug absorption? pH effect on drug absorption Blood flow at the absorption site Area or surface available for absorption Con...
What factors influence drug absorption?
pH effect on drug absorption
Blood flow at the absorption site
Area or surface available for absorption
Contact time with the absorption surface
Expression of P-glycoprotein
The pH effect on drug absorption is related to the ionization of weak acids and bases.
The higher the blood flow at the absorption site, the more efficient the drug absorption.
The larger the area or surface available for absorption, the more efficient the drug absorption.
The longer the contact time with the absorption surface, the more efficient the drug absorption.
P-glycoprotein is a transmembrane protein responsible for transporting various molecules, including drugs, across the cell membrane.
a) I, II, III, IV and V are correct.
b) I, II, III and IV are correct.
c) II, III, IV and V are correct.
d) I, III, IV and V are correct.
pH effect on drug absorption
Blood flow at the absorption site
Area or surface available for absorption
Contact time with the absorption surface
Expression of P-glycoprotein
The pH effect on drug absorption is related to the ionization of weak acids and bases.
The higher the blood flow at the absorption site, the more efficient the drug absorption.
The larger the area or surface available for absorption, the more efficient the drug absorption.
The longer the contact time with the absorption surface, the more efficient the drug absorption.
P-glycoprotein is a transmembrane protein responsible for transporting various molecules, including drugs, across the cell membrane.
a) I, II, III, IV and V are correct.
b) I, II, III and IV are correct.
c) II, III, IV and V are correct.
d) I, III, IV and V are correct.
💡 1 Resposta
Ed 
A alternativa correta é a letra "b) I, II, III e IV estão corretas". Os fatores que influenciam a absorção de drogas são: o efeito do pH na absorção de drogas, o fluxo sanguíneo no local de absorção, a área ou superfície disponível para absorção e o tempo de contato com a superfície de absorção. A expressão da glicoproteína P também pode influenciar a absorção de drogas, mas não é mencionada em todas as alternativas.
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