What is the mechanism of action of the antibiotic chloramphenicol? Inhibits protein synthesis in bacterial ribosomes and mitochondria. Causes an i...
What is the mechanism of action of the antibiotic chloramphenicol?
Inhibits protein synthesis in bacterial ribosomes and mitochondria.
Causes an increase in the number of mitochondrial cristae.
Acts by correcting mutations in mitochondrial DNA.
Is used to treat diseases caused by defects in nuclear DNA.
a) I and II are correct.
b) II and III are correct.
c) I and IV are correct.
d) II and IV are correct.
Inhibits protein synthesis in bacterial ribosomes and mitochondria.
Causes an increase in the number of mitochondrial cristae.
Acts by correcting mutations in mitochondrial DNA.
Is used to treat diseases caused by defects in nuclear DNA.
a) I and II are correct.
b) II and III are correct.
c) I and IV are correct.
d) II and IV are correct.
💡 1 Resposta
Ed 
A alternativa correta é a letra A) I e II estão corretas. O cloranfenicol é um antibiótico que age inibindo a síntese proteica nas bactérias, tanto nos ribossomos bacterianos quanto nos mitocondriais. Isso ocorre porque o cloranfenicol se liga à subunidade 50S do ribossomo, impedindo a formação de ligações peptídicas entre os aminoácidos e, consequentemente, a síntese de proteínas. Além disso, o cloranfenicol pode atravessar a membrana mitocondrial e inibir a síntese proteica nas mitocôndrias bacterianas.
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