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<p>Title: Dynamics of Chemical Diversity During Co-cultures: An</p><p>Integrative Time-scale Metabolomics of Fungal Endophytes</p><p>Cophinforma mamane and Fusarium solani</p><p>Authors: Asih Triastuti, Mohamed Haddad, Fatima Barakat, Patricia</p><p>Jargeat, Gabriel Rabouille, Nicolas Fabre, Carlos Amasifuen,</p><p>Kember Mejia, and Marieke Vansteelandt</p><p>This manuscript has been accepted after peer review and appears as an</p><p>Accepted Article online prior to editing, proofing, and formal publication</p><p>of the final Version of Record (VoR). This work is currently citable by</p><p>using the Digital Object Identifier (DOI) given below. The VoR will be</p><p>published online in Early View as soon as possible and may be different</p><p>to this Accepted Article as a result of editing. Readers should obtain</p><p>the VoR from the journal website shown below when it is published</p><p>to ensure accuracy of information. The authors are responsible for the</p><p>content of this Accepted Article.</p><p>To be cited as: Chem. Biodiversity 10.1002/cbdv.202000672</p><p>Link to VoR: https://doi.org/10.1002/cbdv.202000672</p><p>http://crossmark.crossref.org/dialog/?doi=10.1002%2Fcbdv.202000672&domain=pdf&date_stamp=2020-12-07</p><p>Chem. Biodiversity</p><p>1</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>2</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>3</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>4</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>5</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>6</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>7</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>8</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>9</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>10</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>11</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>http://blast.ncbi.nlm.nih.gov/Blast.cgi</p><p>Chem. Biodiversity</p><p>12</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>13</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>14</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>15</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>16</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p><p>Chem. Biodiversity</p><p>17</p><p>Entry for the Graphical Illustration ((required for publication))</p><p>((Insert Graphical Abstract here; max. width: 17.5 cm; max. height: 7.0 cm))</p><p>10.1002/cbdv.202000672</p><p>A</p><p>cc</p><p>ep</p><p>te</p><p>d</p><p>M</p><p>an</p><p>us</p><p>cr</p><p>ip</p><p>t</p><p>Chemistry & Biodiversity</p><p>This article is protected by copyright. All rights reserved.</p>