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<p>5' 3' U Deamination converts a cytosine base into a uracil. G 3' 5' nucleotide minus base 5' 3' The uracil is detected and III removed, leaving a base-less G nucleotide. 3' 5' 5' 3' The base-less nucleotide is II removed, leaving a small hole G in the DNA backbone. 3' 5' new, correct nucleotide 5' 3' C The hole is filled with the right III II base by a DNA polymerase, and G the gap is sealed by a ligase. 3' 5'</p>