The results of the trial comparing placebo, chlorpromazine, and imipramine in hospitalized patients, including pseudoneurotic schizophrenics, showed that there was a significant drug-placebo effect for imipramine in terms of global improvement. However, no significant drug-placebo effect was found for chlorpromazine. The trial was randomized and double-blind and included 311 hospitalized patients, including 32 pseudoneurotic schizophrenics.
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