What are the characteristics of determinants recognized by T cells? I- They are created by the primary sequence of amino acids in proteins. II- Th...
What are the characteristics of determinants recognized by T cells?
I- They are created by the primary sequence of amino acids in proteins.
II- They can be located on the surface of the antigen.
III- They are limited to approximately 8-15 amino acids.
IV- The number of antigenic determinants per antigen is very high.
a) I and II are correct.
b) I and III are correct.
c) II and IV are correct.
d) I and III are correct.
I- They are created by the primary sequence of amino acids in proteins.
II- They can be located on the surface of the antigen.
III- They are limited to approximately 8-15 amino acids.
IV- The number of antigenic determinants per antigen is very high.
a) I and II are correct.
b) I and III are correct.
c) II and IV are correct.
d) I and III are correct.
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Ed 
A alternativa correta é a letra b) I e III estão corretas. Os determinantes antigênicos reconhecidos pelas células T são peptídeos curtos, geralmente com cerca de 8 a 15 aminoácidos, que são criados pela degradação proteolítica de proteínas endógenas ou exógenas. Esses peptídeos são apresentados na superfície de células apresentadoras de antígenos (APCs) ligados a moléculas do complexo principal de histocompatibilidade (MHC) de classe I ou II.
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