What is the sequence of events in the termination of transcription in bacteria E. coli? I- There are two basic mechanisms of transcription termina...
What is the sequence of events in the termination of transcription in bacteria E. coli?
I- There are two basic mechanisms of transcription termination in E. coli.
II- The first mechanism is called direct (intrinsic) termination and involves a DNA sequence that signals the end of transcription.
III- The second mechanism is called Rho-dependent termination and involves a protein called Rho factor.
IV- Rho factor is a protein with approximately 40,000 Daltons that acts as a hexamer with 275,000 Daltons.
V- Rho factor binds to the nascent RNA molecule at specific sites called rut sites.
VI- Rho factor interacts directly with the RNA polymerase to induce a conformational change that leads to pausing.
a) I, II, and IV are correct.
b) II, III, and V are correct.
c) III, IV, and VI are correct.
d) I, III, and V are correct.
I- There are two basic mechanisms of transcription termination in E. coli.
II- The first mechanism is called direct (intrinsic) termination and involves a DNA sequence that signals the end of transcription.
III- The second mechanism is called Rho-dependent termination and involves a protein called Rho factor.
IV- Rho factor is a protein with approximately 40,000 Daltons that acts as a hexamer with 275,000 Daltons.
V- Rho factor binds to the nascent RNA molecule at specific sites called rut sites.
VI- Rho factor interacts directly with the RNA polymerase to induce a conformational change that leads to pausing.
a) I, II, and IV are correct.
b) II, III, and V are correct.
c) III, IV, and VI are correct.
d) I, III, and V are correct.
💡 1 Resposta
Ed 
A sequência correta de eventos na terminação da transcrição em bactérias E. coli é a seguinte: I- Existem dois mecanismos básicos de terminação da transcrição em E. coli. II- O primeiro mecanismo é chamado de terminação direta (intrínseca) e envolve uma sequência de DNA que sinaliza o fim da transcrição. III- O segundo mecanismo é chamado de terminação dependente de Rho e envolve uma proteína chamada fator Rho. A alternativa correta é a letra d) I, III e V estão corretas.
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