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Pág. 282 Guías de Procedimientos en Ginecología Índices de supervivencia general (%) Estadio 5 años Ia1 94,6 Ia2 92,6 Ib1 80,7 Ib2 79,8 IIa 76 IIb 73,3 IIIa 50,5 IIIb 46,4 IVa 29,6 IVb 22 Bibliografía: 1. Whelan, S., Parkin, D., et al. Patterns of cancer on five continent. Lyon, France: Intenational Agency for Research on Cancer, 1990. 2. Jemal, A., Tiwai, R., et al. Cancer statistics 2003. Cancer J Clinics, 2004; 54: 529 3. Walboomers, J., Jaikobs, M., et al. Human oapiloma virus. Necessary cause of invasive cervical cancer world wide. J Pathol , 1999; 189: 1219 4. DiSaia, P. Oncología Ginecológica Clínica. Madrid, 1999. 5ta edición, Harcourt Brace. 5. The 1988 Bethesda System for reporting cervical/vaginal cytological diagnoses. National Cancer Institute Workshop. JAMA 262 (7): 931-4, 1989 6. Landoni F, Maneo A, Colombo A, et al.: Randomised study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer. Lancet 350 (1977): 535-40, 1997. 7. NCI 8. Cunningham MJ, Dunton CJ, Corn B, et al.: Extended-field radiation therapy in early-stage cervical carcinoma: survival and complications. Gynecol Oncol 43 (1): 51-4, 1991. 9. Downey GO, Potish RA, Adcock LL, et al.: Pretreatment surgical staging in cervical carcinoma: therapeutic efficacy of pelvic lymph node resection. Am J Obstet Gynecol 160: 1055-61, 1989 10. Keys HM, Bundy BN, Stehman FB, et al.: Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med 340 (15): 1154-61, 1999 11. Thoms WW Jr, Eifel PJ, Smith TL, et al.: Bulky endocervical carcinoma: a 23-year experience. Int J Radiat Oncol Biol Phys 23 (3): 491-9, 1992 12. Patel FD, Sharma SC, Negi PS, et al.: Low dose rate vs. high dose rate brachytherapy in the treatment of carcinoma of the uterine cervix: a clinical trial. Int J Radiat Oncol Biol Phys 28 (2): 335-41, 1994. . 13. Hareyama M, Sakata K, Oouchi A, et al.: High-dose-rate versus low-dose-rate intracavitary therapy for carcinoma of the uterine cervix: a randomized trial. Cancer 94 (1): 117-24, 20 14. Lertsanguansinchai P, Lertbutsayanukul C, Shotelersuk K, et al.: Phase III randomized trial comparing LDR and HDR brachytherapy in treatment of cervical carcinoma. Int J Radiat Oncol Biol Phys 59 (5): 1424-31, 2004 15. Nag S, Chao C, Erickson B, et al.: The American Brachytherapy Society recommendations for low-dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 52 (1): 33-48, 2002. 16. Nag S, Erickson B, Thomadsen B, et al.: The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 48 (1): 201-11, 2000. 17. Rose PG, Bundy BN, Watkins EB, et al.: Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 340 (15): 1144-53, 1999. 18. Peters WA 3rd, Liu PY, Barrett RJ 2nd, et al.: Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol 18 (8): 1606-13, 2000 19. Thomas GM: Improved treatment for cervical cancer—concurrent chemotherapy and radiotherapy. N Engl J Med 340 (15): 1198-200, 1999 20. Sardi, J., Giaroli, A.., et al. Long-term follow-up of the first randomized trial using neoadjuvant chem otherapy in stage Ib squamous carcinoma of the cervix: the final results. Gynecol Oncol, 1997; 67:61-9 21. Sardi J., Sananes, C., et al. Results of a prospective randomized trial with neoadjuvant chemotherapy in stage IB, bulky, squamous carcinoma of the cervix. Gynecol Oncol, 1993; 49:156-65
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