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ORIGINAL ARTICLE Understanding technology adoption by orthodontists: A quantitative study Laura Anne Jacox,a Clare Bocklage,a Teresa Edwards,b Paul Mihas,b Feng-Chang Lin,c and Ching-Chang Kod Chapel Hill, NC, and Columbus, Ohio aDivis of No bHow Caroli cDepa of No dDivis of No Denti All au Poten This w Resea to Ch ship f Assoc Fellow Gradu the U award Assoc Found Addre of De e-mai Subm 0889- � 202 https: 364 Introduction: Digital scanning, treatment planning, 3-dimensional imaging, and printing are changing the practice of orthodontics. These tools are adopted with the hope that treatment becomes more predictable, efficient, and effective while reducing adverse outcomes. Digital tools are impacting care, but knowledge of nationwide adoption trends and motivators is incomplete. Methods: We aimed to identify adoption decision- makers, information sources, incentives, and barriers through the first nationwide survey of American Association of Orthodontics members on their technology adoption habits, needs, and outcomes. Data were assessed using descriptive and bivariate analyses. The survey was developed from a comprehensive qualitative interview phase as part of a mixed methodology study. Results: Responses (n 5 343) revealed or- thodontists make adoption decisions on the basis of advice from other dentists and company representatives while rarely consulting staff or research literature. Continuing education and meetings are most effective at disseminating information to practicing doctors, whereas journals generate less impact. Key adoption incentives include added capabilities, practice efficiency, ease of implementation, and performance, whereas cost is the main barrier to purchase. Early adopters with larger practices charge higher fees than other adopters to support the costs of technologies. Treatment outcome is not a primary adoption incentive for specific technologies. Conclusions: Orthodontists positively perceive the influence of intraoral scanning, cone-beam computed tomography imaging, 3-dimensional printing, computer-aided design–computer-aided manufacturing archwires, and clear aligner therapy on their practice and patient care. The orthodontic technological transformation is underway, and knowledge of adoption can guide our transition into modern practice, in which digital tools are effective adjuncts to the specialists' expertise. (Am J Orthod Dentofacial Orthop 2022;161:364-74) ion of Craniofacial and Surgical Care, Adams School of Dentistry, University rth Carolina, Chapel Hill, NC. ard W. Odum Institute for Research in Social Science, University of North na, Chapel Hill, NC. rtment of Biostatistics, Gillings School of Global Public Health, University rth Carolina, Chapel Hill, NC. ion of Craniofacial and Surgical Care, Adams School of Dentistry, University rth Carolina, Chapel Hill, NC; currently, Division of Orthodontics, College of stry, The Ohio State University, Columbus, Ohio. thors have completed and submitted the ICMJE Form for Disclosure of tial Conflicts of Interest, and none were reported. ork was supported by the National Institute of Dental and Craniofacial rch at the National Institutes of Health (grant no. R01DE022816; award ing-Chang Ko) and the University of North Carolina (UNC) Hale Professor- und (award to Ching-Chang Ko). This work was funded by the American iation of Orthodontists Foundation Martin ‘Bud’ Schulman Postdoctoral ship (award to Laura Anne Jacox). This work was also supported by the ate School Masters Merit Assistantship for study in Dentistry awarded by NC Graduate School, the Southern Association of Orthodontics research , and the Masters Research Support Grant awarded by the Office of the iate Dean for Research at UNC Adams School of Dentistry and the Dental ation of North Carolina (awards to Laura Anne Jacox). ss correspondence to: Ching-Chang Ko, Division of Orthodontics, College ntistry, Ohio State University, 4088A Postle Hall, Columbus, OH 43210; l, ko.367@osu.edu. itted, April 2020; revised and accepted, August 2020. 5406/$36.00 1. //doi.org/10.1016/j.ajodo.2020.08.024 Technology is changing how orthodontists deliver care.1,2 Traditionally, patients begin treatment with alginate impressions; 2-dimensional radio- graphs; and bonded straight wire appliances that require monthly, chair-side modifications to achieve an ideal finish.3 In a digital office, patients begin with an intrao- ral and cone-beam computed tomography (CBCT) scan, followed by a digital tooth setup and fabrication of custom appliances including clear aligners (eg, Invisa- lign, U-Lab, Orchestrate), computer-aided design– computer-aided manufacturing (CAD-CAM) brackets (eg, Insignia, Incognito), or prebent CAD-CAM archwires (eg, SureSmile).4 The orthodontist spends nonpatient hours digitally planning treatment. Subsequent patient appointments can be shorter and more widely spaced, especially with clear aligners. The doctor tracks progress and compliance as the appliances execute planned movements until intervention or revision is needed. This change in workflow opens the door for remote treatment monitoring, teledentistry, and market disrup- tors like direct-to-consumer aligners.4 Jacox et al 365 Despite the excitement for and adoption of these tools, it is ambiguous whether digital approaches improve outcomes and efficiency, as results vary between products and studies.5-10 CAD-CAM brackets were initially more effective and efficient than standard appliances, but subsequent studies have found minimal improvement in outcome and treatment times.6,9,10 Robotically bent archwires are associated with reduced treatment times, but data on finish quality are conflicting.5,7,8,10 Although much improvement is needed, future development is likely to offer safer, more efficient, and effective orthodontic treatment, necessitating the adoption of the digital workflow.5-10 For digital workflows to improve care, orthodontists must effectively integrate technologies and track outcome metrics. Widespread adoption of digital tech- nologies is occurring, but we have an incomplete under- standing of how orthodontic practice is shaped by these tools and which factors impact technology dissemina- tion.11,12 To understand the current technology land- scape, we conducted a 2-phase, mixed methodology study to identify orthodontic decision-makers, informa- tion sources, incentives, and barriers for technology adoption. The first phase consisted of qualitative semistructured interviews with 24 privately practicing orthodontists, most affiliated as adjunct faculty in the graduate orthodontic programs at the University of North Carolina (UNC) Adams School of Dentistry and Harvard School of Dental Medicine.13 These interviews allowed us to identify key factors in the technology adoption process. To test the generalizability of our findings, we developed and distributed the first national survey on technology adoption of American Association of Orthodontics (AAO) members. Results provide quanti- tative insight into the state of technology adoption by orthodontists and can be used to guide innovation and information dissemination. MATERIAL AND METHODS This survey is the second part of a 2-phase, mixed- methods investigation in which we used qualitative in- terviews to identify factors important to technology adoption with the breadth and depth, followed by a quantitative survey to measure the generalizability of our findings.13 Results from our qualitative study guided the devel- opment of an online survey to assess technology adoption, influence, and future needs among the mem- bership of the AAO. For example, we learned in qualita- tive interviews that technology cost, performance, and ease of use are key adoption factors, which we incorpo- rated into the quantitative survey as options for why American Journal of Orthodontics and Dentofacial Orthoped technology was adopted or forgone. Because of a lack of validated questions available for this topic, published questionnaires were referenced,and questions were developed from our qualitative findings by the authors with significant input from a sociologist working in ed- ucation (Paul Mihas), an expert in survey development (Teresa Edwards), a biostatistician (Feng-Chang Lin), and an orthodontic faculty member (Ching-Chang Ko) to ensure representation of different viewpoints.2,14 The survey was fully pretested with probe questions by 8 orthodontic residents, 8 privately practicing doctors, and 2 academic orthodontic faculty at UNC Adams School of Dentistry following methods recommended by Willis, 2005.15 Probes were used to explore the ques- tion interpretation and identify points of ambiguity. The survey was iteratively revised on the basis of feedback to improve clarity. The survey consists of 30 demographic questions about the orthodontist and their primary place of work. These first 30 questions are identical across re- spondents, but later questions are customized using a preprogrammed decision tree in Qualtrics to display questions on the basis of which technologies doctors had used or forgone. The decision tree presents 6-10 questions asking about adopted tools, the influence of those tools, and avoided or abandoned technologies. As a result, each participant did not answer all questions about every technology but instead had a customized survey experience on the basis of their adoption history. This is reflected in a lower number of responses for questions on specific tools than the total participant pool. For example, if a doctor uses an intraoral scanner, the participant was asked why the practice purchased the scanner and how they perceived its influence in the of- fice. Alternatively, if an orthodontist had not used a 3- dimensional (3D) printer, they were asked why they had not adopted this technology. All methods were approved by the Institutional Re- view Board and the Office of Human Research Ethics of the UNC at Chapel Hill (Institutional Review Board no. 16-2743). Survey questions were submitted to the AAO Partners in Research Program for review and approval. Once approved, the AAO randomly selected 2,300 members with registered e-mail addresses to be contacted with informed consent documentation and a Qualtrics link for survey participation. Recipients were randomly selected from their total membership after nonqualifying members were excluded (Table I). Our sample includes actively practicing doctors in private or corporate clinics in the United States and Canada, excluding all current residents, retired doctors, recent graduates (\2 years of practice), full-time academics, public health doctors, ics March 2022 � Vol 161 � Issue 3 Table I. Survey inclusion and exclusion criteria Criteria Description Inclusion � An orthodontist who practices in a private orthodontics clinic that is orthodontics-only or a group multispecialty practice � An orthodontist can be an associate, partner, or sole owner of the practice in which they work � A doctor must have been actively working in private practice for .2 y and must provide informed consent � Member of the AAO Exclusion � A doctor who does not practice privately (eg, academic-only or public health orthodontists) � An orthodontist who has been practicing for\2 y in private practice � Current orthodontic residents � Retired doctors 366 Jacox et al hospital-based orthodontists, and doctors in other countries (Tables I and II; Supplementary Table I). Screening questions ensured all participants met inclu- sion criteria. Orthodontists who did not fill out the sur- vey within a week received a second e-mail, distributed at a different time and day to maximize responses. The survey was conducted through the UNC Qualtrics li- cense, and data was stored securely and deidentified. After an initial distribution and reminder e-mail, the AAO authorized an additional distribution to boost re- sponses. An additional 2,300 members were randomly selected from the total membership using the same inclu- sion and exclusion criteria (Table I) while excluding all previously emailed doctors. Therefore, a total of 4,600 AAO randomly selected members were emailed in both distribution waves, with a total combined response rate of 7.4% with 343 responses (Supplementary Table I). Although our response rate is on the low end of recent technology surveys, with average response rates of 7%- 11%, our survey was longer and more complex, leading to a higher incidence of partial completion.14,16 Responses were categorized as being from an early, middle, or late adopter on the basis of screening ques- tions. Participants were asked how often they were among the first people in their professional dental network or community to try a new technology or prod- uct. Early adopters self-reported as always or usually, while late adopters self-reported rarely or never explored new products. Self-reporting can be biased, so group- ings were revised relative to 3 follow-up questions. Doc- tors were asked if they are part of a corporate insider's group and if they participate in beta-testing new prod- ucts for companies, features of early adopters; if a doctor answered yes to either of these questions, they were moved to the early adopter group. Participants were also asked which technologies they had tried. Doctors who tried all technologies were moved to the early adopter category, whereas doctors who tried no technol- ogies were categorized as late adopters. Orthodontists who tried more than half of technologies while answering that they rarely or never explored new prod- ucts were moved from the late to middle pool. Middle adopters were practitioners who did not meet the criteria for being late or early adopters. Participants were indi- vidually reviewed to ensure group assignment was logi- cally consistent with their adoption history. Data analysis Survey data were assessed using descriptive and bivariate analyses. Descriptive statistics such as mean, standard deviation, and percentage are reported for collected variables. Bivariate association analysis March 2022 � Vol 161 � Issue 3 American between demographic variables and questions (scales) were explored using t tests, F tests, and chi-square tests when appropriate. Responses with continuous variables were analyzed using unpaired t tests for pairwise com- parisons and 1-way analysis of variance for the 3 adopter groups. Categorical data were assessed using the chi- square test. Multiple-choice questions in which respon- dents could choose up to 3 answers or as many options as desired are reported as frequencies with pairwise com- parisons by chi-square test. Final analyses were weighted by inverse probability weights that balance the sample to represent the whole population. RESULTS To understand the adoption process, we surveyed who is making purchasing decisions and where they learn about new technologies. Consistent with qualita- tive findings, 89% of orthodontic practice owners, partners, and associates participate in purchasing conversations, but adoption decisions are made with minimal staff input, regardless of the adopter group (Supplementary Table II). Assistants are consulted by only 16% of respondents, whereas 16% of office man- agers are included in discussions. Front desk, treatment coordinators, financial staff, and laboratory technicians are involved in purchasing choices by\10% of owners. Our qualitative data revealed that doctors leave staff out of the adoption process believing they are resistant to change, but owners are committed to thorough training with the goal of staff buy-in once a product is purchased.13 To identify information sources for adoption, ortho- dontists were asked how they first heard about technol- ogies and what resources are consulted for more Journal of Orthodontics and Dentofacial Orthopedics Table II. Practice demographics Demographics Adopter group P Early adopter (n 5 69) Middle adopter (n 5 177) Late adopter (n 5 97) Total (n 5 343) Appliances used at practice, % Traditional twin/edgewisebrackets 53 (77) 143 (81) 84 (87) 280 (82) 0.237 Self-ligating brackets 42 (61) 93 (53) 36 (37) 171 (50) 0.006 Clear aligners produced off-site (eg, Invisalign, ClearCorrect) 63 (91) 154 (87) 86 (89) 303 (88) 0.662 Clear aligners produced in-house, excluding active retainers (eg, Orchestrate) 32 (46) 34 (19) 5 (5) 71 (21) \0.001 Custom CAD-CAM lingual brackets (eg, Incognito, Harmony) 10 (14) 6 (3) 3 (3) 19 (6) 0.004 Custom CAD-CAM buccal brackets (eg, Insignia) 3 (4) 7 (4) 0 (0) 10 (3) 0.101 Custom bent CAD-CAM archwires (eg, Suresmile) 14 (20) 8 (5) 0 (0) 22 (6) \0.001 Patients treated with clear aligners, % 27.6 (20.2) 18.7 (16.3) 13.4 (11.8) 19.0 (16.8) \0.001 Patients receiving CBCT scans, % 28.2 (39.0) 14.4 (28.8) 6.20 (17.3) 14.8 (29.5) \0.001 Practice organization 0.020 Private orthodontics-only practice 58 (88) 130 (80) 72 (76) 260 (80) 0.161 Private multispecialty group practice 5 (8) 19 (12) 5 (5) 29 (9) 0.216 Corporate/DSO orthodontics-only practice 3 (5) 7 (4) 8 (8) 18 (6) 0.365 Corporate/DSO multispecialty group practice 0 (0%) 6 (4%) 10 (11%) 16 (5%) 0.005 Practice setting, % 0.901 Large city 22 (33) 45 (27) 25 (26) 92 (28) Small to medium city 12 (18) 33 (20) 17 (18) 62 (19) Suburb 21 (32) 53 (32) 29 (31) 103 (32) Rural 0 (0) 1 (1) 0 (0) 1 (0) Small to medium town 11 (17) 33 (20) 24 (25) 68 (21) Note. Values are percent mean (standard deviation). Jacox et al 367 information. As in our interview sample, the majority of doctors (72%) first hear about new technologies from other orthodontists and turn to colleagues to learn more about products (Supplementary Table III). Con- sistent with our qualitative data, the importance of person-to-person exchange extends to company repre- sentatives, which act as the second most cited source of initial and follow-up information for new tools (42%; Supplementary Table III). Conferences and live continuing education lectures are another significant in- formation source (41%; Supplementary Table III). All other sources were cited by less than one-third of re- spondents. Only about a quarter of orthodontists turn to academic journals to learn about technologies, similar to our interview cohort in which 17% cited journals as a resource.13 Social media reaches nearly as many ortho- dontists as published literature (Supplementary Table III). These data suggest conference continuing education is a more effective way to disseminate knowledge to practicing doctors than academic journals. Once some orthodontists are aware of technology, information is then dispersed to the dental community. Technology acquisition varies greatly among early, middle, and late adopters. To outline differences be- tween groups, we looked at practice characteristics and demographics. Notable trends emerged regarding American Journal of Orthodontics and Dentofacial Orthoped tech adoption, practice fees, and size. Early adopters began more patients per year than other groups, and early and middle adopters had significantly higher fees than late adopters (Fig 1; Supplementary Table IV). Late adopters' fees for nonextraction and extrac- tion patients fall well below the national average for comprehensive treatment of an adolescent ($5,748.17 6 $521.97; American Dental Association 2018 Sur- vey), whereas early and middle adopters charge fees consistent with the average for nonextraction (Fig 1; Supplementary Table IV).17 A larger fraction of late adopters is working in corporate offices, in which they may lack purchasing autonomy (Table II). There was no statistically significant difference in staff size between groups, meaning early adopters start more patients and charge more per patient, with similar staff overhead, relative to later adopters (Fig 1; Supplementary Table IV). Consistent with our qualita- tive findings, differences in patient starts and collec- tions per patient suggest that a more lucrative practice is required to support the cost and time re- quirements of technology integration. No significant trends were found relative to an ortho- dontists' age, gender, ethnicity, time in practice, resi- dency program, or practice setting (eg, rural or suburban) (Table II; Supplementary Table I). ics March 2022 � Vol 161 � Issue 3 Fig 1. Average fee, patient starts, and staff size by adopter group. A, Average fees for a nonextraction and extraction, comprehensive adolescent patient by adopter group.Arrow: The 2018 national average for comprehensive treatment of an adolescent, published by the American Dental Association, is $5,748.17 6 $521.97.17 B, Average patient starts per year by adopter group. C, Average staff size by adopter group. 368 Jacox et al Adopter categories vary greatly in their usage of appliances and technologies. Early and middle adopters are significantly more likely to use self- ligating brackets than late adopters (Table II; Supplementary Table V). Early adopters use CAD- CAM wires (eg, Suresmile) and have begun producing in-house clear aligners at a greater frequency than others (Table II; Supplementary Table V). Early adopters also order CBCT imaging and prescribe clear aligner therapy for a higher fraction of patients (Table II; Supplementary Table V). There is no significant dif- ference in the current use of twin brackets and clear aligners produced off-site (eg, Invisalign), indicating some level of universal adoption. More early adopters tried CAD-CAM brackets than middle and late adopters at some time, but there is no significant difference in the current use of custom buccal brackets, suggesting early adopters abandoned these appliances. The prac- tice of orthodontics differs between groups, with early adopters using newer appliances and imaging modal- ities than middle and late adopters. March 2022 � Vol 161 � Issue 3 American To understand what motivates a doctor to purchase or forgo a technology, orthodontists were asked what factors are most important when considering adoption. We hypothesized that primary factors include cost, capa- bilities, practice efficiency, ease of implementation, and performance on the basis of our qualitative findings.13 As anticipated, cost and return on investment were most frequently identified as important across all groups (Table III). Effect on treatment outcome is commonly cited, along with the impact on workflow and efficiency (Table III). More late and middle adopters are concerned with a product's user-friendliness, whereas early adopters focus on patient preference. Middle adopters consider reduced treatment time or office visits more often. Broadly considering factors for acquisition is insightful, but to fully understand the adoption story, we asked orthodontists specifics about technologies they regularly use, why certain tools were acquired, and others were never purchased. Across all groups and technologies, the adoption barrier most commonly Journal of Orthodontics and Dentofacial Orthopedics Table III. Important adoption factors by adopter group Adoption factors Adopter group P Early adopter (n 5 67) Middle adopter (n 5 169) Late adopter (n 5 96) Total (n 5 332) Costs, overhead, and return on investment 50 (74.6) 125 (74.0) 78 (81.2) 253 (76.2) 0.389 Treatment outcome 47 (70.1) 119 (70.4) 63 (65.6) 229 (69.0) 0.706 Practice workflow and efficiency 29 (43.3) 68 (40.2) 42 (43.8) 139 (41.9) 0.825 User-friendly, easy to implement 15 (22.4) 42 (24.9) 25 (26.0) 82 (24.7) 0.875 Equipment performance (fast, accurate, reliable, no bugs) 13 (19.4) 28 (16.6) 23 (24.0) 64 (19.3) 0.327 Satisfies patient preferences or requests 15 (22.4) 24 (14.2) 14 (14.6) 53 (16.0) 0.279 Reduced office visits and/or total treatment time 9 (13.4) 31 (18.3) 12 (12.5) 52 (15.7) 0.452 Added diagnostic value 9 (13.4) 26 (15.4) 9 (9.4) 44 (13.3) 0.401 Additional capabilities 10 (14.9) 19 (11.2) 3 (3.1) 32 (9.6) 0.017 Marketing and word of mouth 4 (6.0) 12 (7.1) 2 (2.1) 18 (5.4) 0.197 Note. Values are percent mean (standard deviation). Jacox et al 369 cited was cost and overhead, yet reducing overhead is asignificant incentive only for 3D printing and in-house aligner production (Figs 2 and 3; Supplementary Tables VI and VII). Cost is largely an impediment to acquisition rather than a motivator for most tools. This is similar to technology performance which dissuades the purchase of 3D printers, intraoral scanners, and off-site aligners, whereas excellent performance is rarely cited as an incentive (Figs 2 and 3; Supplementary Tables VI and VII). Space requirements for an intraoral scanner and 3D printer are also considerations. Implementation of CAD-CAM appliances and in- house 3D printing for aligners is difficult and potentially detrimental to practice workflow. Effect on practice workflow and efficiency is a frequent barrier and incen- tive for most technologies, pointing to the importance of workflow integration. Furthermore, CAD-CAM appli- ances are perceived to offer the same or worse treatment outcomes with higher overhead and inefficiency (Figs 2 and 3; Supplementary Tables VI and VII). However, improved treatment outcomes were also a primary incentive for CAD-CAM appliance adoption, suggesting clinicians have markedly different experiences imple- menting more complex technologies. When asked broadly about adoption factors, addi- tional capabilities are rarely an incentive, contrary to our qualitative results (Figs 2 and 3; Supplementary Tables VI and VII).13 However, when doctors are asked about specific technologies, added capabilities are a commonly cited incentive across all tools and adopters. This suggests doctors are more aware of their motiva- tors when considering specific examples and that our interview sample was representative. Similarly, treat- ment outcome is a regularly chosen factor when asked broadly about adoption factors, but it is an infrequent motivator for all tools except CAD-CAM brackets and American Journal of Orthodontics and Dentofacial Orthoped wires. Treatment outcome ranked eigth in importance in our qualitative results.13 Treatment outcome is crit- ical to orthodontists, but when considering specific technologies, it is selected less often than cost, ease of integration, and impact on efficiency. The patient request drives esthetic treatment modalities and intrao- ral scanning, as satisfying the customer leads to con- versions. Orthodontists care for their patients, but they are running businesses requiring optimization for practice economics, efficiencies, and patient con- versions. Data are consistent with our hypothesis that primary adoption factors include cost, added capabil- ities, practice efficiency, ease of implementation, and performance. Adopters of technology were asked to reflect on how their digital tool influenced their practice and patient care. Each doctor was asked about technologies they recently adopted on the basis of the survey's decision tree; as a result, the total number of responses for each technology was lower than the total sample of the survey, with more commonly adopted digital tools having more responses (Supplementary Table VIII: in- traoral scanner n 5 223; Supplementary Table IX: 3D printer n 5 48; Supplementary Table X: CBCT n 5 46; Supplementary Table XI: CAD-CAM archwires n 5 18; Supplementary Table XII: CAD-CAM brackets n 5 16; Supplementary Table XIII: laboratory-fabricated clear aligners n 5 262; Supplementary Table XIV: in-house fabricated clear aligners n 5 47). The intraoral scanner and 3D printer were seen by most doctors as having a positive effect on improving practice capabilities, efficiency, and workflow while also addressing patient preferences (Supplementary Tables VIII–IX). Both tech- nologies provided a marketing advantage, whereas the intraoral scanner improved the storage needs of practice by eliminating plaster models. ics March 2022 � Vol 161 � Issue 3 Fig 2. Barriers to adoption by technology. The primary barrier is the factor includedmost often for why a doctor is not considering purchasing a technology. The secondary barrier is the factor selected second most frequently for why a doctor is not considering a tool. The number in (parentheses) is the number of responses associated with a factor for a particular technology. Each factor was associated randomly with a color to aid in visual evaluation. Not all responders answered all questions because they had adopted the technology or the display logic decision tree limited the number of questions. 370 Jacox et al As imaging modalities, CBCT and intraoral scanning were seen as improving orthodontist's diagnostic ability and practice capabilities (Supplementary Tables VIII and X). CBCT imaging also enhanced treatment outcomes without impacting treatment time, office visits, or work- flow (Supplementary Table X). CBCT increased operating costs for a majority of doctors, whereas intraoral scan- ning did not (Supplementary Tables VIII and X). CAD-CAM archwires (SureSmile) were positively re- viewed by most doctors and were seen as improving treatment outcomes, practice workflow, and capabilities while reducing treatment time and the number of office visits (Supplementary Table XI). However, the feedback on CAD-CAM brackets was markedly more negative than for CAD-CAM archwires in survey responses and prior interviews, although our sample size was small.13 The majority responded that custom brackets had no ef- fect or a negative effect on practice workflow, treatment outcomes, total treatment time, and the number of of- fice visits (Supplementary Table XII). CAD-CAM brackets did enhance practice capabilities and provided a slight marketing edge for most doctors. With the sizable March 2022 � Vol 161 � Issue 3 American overhead associated with CAD-CAM technologies, custom wires appear to be the preferable investment over brackets: a topic worth exploring with a larger cohort of CAD-CAM adopters. Another promising CAD-CAM product is the nearly ubiquitous clear aligner therapy. Laboratory-produced clear aligners (eg, Invisalign, ClearCorrect) had numerous positive repercussions, including reducing of- fice visits, addressing patient requests for esthetic treat- ment, and boosting practice capabilities, marketing, and workflow efficiency (Supplementary Table XIII). For a majority of orthodontists, lab fabricated clear aligners, CAD-CAM wires, and brackets had a negative impact on overhead and operating costs because of their sizable laboratory fees (Supplementary Tables XI–XIII). In contrast, manufacturing clear aligners in-house reduced overhead, as practices bypassed laboratory costs (Supplementary Table XIV). In-house aligners also satis- fied patients' desires for esthetics and enhanced practice capabilities. However, most doctors reported that in- house aligners did not affect the number of office visits, unlike laboratory-produced aligners. All aligners, both Journal of Orthodontics and Dentofacial Orthopedics Fig 3. Incentives for adoption by technology. The primary incentive is the factor included most often for why a doctor is considering purchasing a technology. The secondary incentive is the factor selected second most frequently for why a doctor is considering a tool. The number in (parentheses) is the num- ber of responses associated with a factor for a particular technology. Each factor was associated randomly with a color to aid in visual evaluation. Not all responders answered all questions because they had adopted the technology or the display logic decision tree limited the number of questions. Jacox et al 371 in-house and laboratory-fabricated, were seen as neither helping nor hurting treatment outcomes and treatment time by most doctors. Treatment was still guided by the practitioner, not the appliance. Across nearly all technologies, a greater fraction of early and middle adopters viewed their digital tools as positively influencing their practices than late adopters, consistent with our qualitative results. DISCUSSION Mixed method studies are rare in the orthodontic literature but allow us to answer nuanced social sciencequestions. To explore a topic as broad and multifaceted as technology adoption, our study required methodo- logical pluralism with a qualitative interview phase fol- lowed by a quantitative survey. Our phase 1 interviews identified factors important to technology adoption because of this format's flexibility to explore topics with depth and breadth.13,18 The results laid the founda- tion for a successful survey, in which we tested the sta- tistical generalizability of our findings with a larger group of participants. This mixed-methods approach American Journal of Orthodontics and Dentofacial Orthoped proves powerful by merging the advantages of qualita- tive research with the pros of quantitative surveys.18 The qualitative research phase generated numerous inductive topics, which we were then able to measure quantitatively using the survey. Through our mixed-methods research, we found practice owners and associates make purchasing deci- sions independently of staff, on the basis of input from other dentists, company representatives, and con- ference continuing education lectures. Academic jour- nals are referenced by only a quarter of doctors looking to adopt a technology, suggesting published data on product efficacy are not reaching private practi- tioners or is reaching them after relevant decisions have already been made. Because of the importance of person-to-person communication, it is critical that sci- entific evidence enters the knowledge food chain to avoid marketing-fueled adoption of unproven technolo- gies at the hands of companies and their representa- tives.19,20 Evidence-based practice can flourish only when evidence is reaching clinicians. As a field, we must reflect on ways to infuse our standard of care ics March 2022 � Vol 161 � Issue 3 372 Jacox et al with up-to-date findings, as academic journals are not fulfilling this role. When research is published in peer- reviewed articles, there is a lag time of at least 6-18 months from data acquisition to publication. For highly relevant findings, this may be too long. Conference continuing education and improved social media and online platforms could be more promising contact points at this time; including a peer-review element to ensure quality control in these formats is the unsolved challenge. Interesting trends emerge regarding features of adopter groups. Early adopters prescribe CBCT scans and clear aligner therapy for a greater fraction of their patients (Table II). Early adopters also use more recent appliances, including self-ligating brackets, CAD-CAM wires, and clear aligners produced in-house with 3D printers and positive pressure fabricators (Table II; Supplementary Table V). CAD-CAM brackets have been tried by significantly more early adopters, but there is no significant difference between groups in current use, which may suggest doctors abandoned these appli- ances after trying them. In our small sample, the main barrier to CAD-CAM appliances is increased cost with no anticipated benefit to treatment outcome or effi- ciency. This perception may stem from early adopters who were dissatisfied with custom brackets, discontin- ued use, and spread the word to their colleagues via the communication hierarchy identified in our qualita- tive study.13 Frequently, early adopters try new technol- ogies and make recommendations to their community of middle and late adopters. CAD-CAM brackets will need notable advances in efficiency and effectiveness for wider adoption to occur and compete with CAD-CAM wires, which are more positively perceived by users (Supplementary Tables XI and XII). Early adopters tend to have privately owned practices with larger patient pools and higher fees on average (Fig 1; Table II). Staff sizes were nearly equivalent between groups, such that the ratio of the patient starts to staff was highest with early adopters. These data could sug- gest more lucrative businesses with more customers, higher fees, and higher patient-to-staff ratios are needed to cover the cost requirements of technology. Alterna- tively, the implementation and adoption of new technol- ogies may help to increase practice size and efficiency. As orthodontics becomes more tech-heavy, there is increased risk to lower-fee, lower volume practices that cannot afford expensive digital tools and practices that are uninterested in tech adoption. Contrary to the qualitative study, which showed early adopters are younger than late adopters, no notable age- relationship was found in our quantitative results (Supplementary Table I). This may be because younger March 2022 � Vol 161 � Issue 3 American doctors have less purchasing autonomy when working as associates and have less available capital when own- ing a recently transitioned practice, preventing them from adopting expensive tools. As a result, young doc- tors are no more likely to adopt a technology than older practitioners, who are approaching retirement and have established systems. Our qualitative interview sample was small and included many doctors practicing in growing or rural areas, who established lucrative prac- tices within a few years of start-up or transition; most doctors were also affiliated with the UNC and Harvard School of Dental Medicine graduate orthodontic resi- dency programs as part-time adjunct faculty, increasing their exposure to new technologies. Therefore, our phase I interview sample was not representative of the greater United States, particularly in saturated urban centers surveyed in our nationwide sample. Another variant be- tween phases I and II occurred in the selection of adop- tion incentives. When orthodontists were surveyed about what, in general, motivates them to buy a tool, the additional capability was rarely chosen while improved treatment outcome was a common selection. However, when doctors were surveyed about specific technologies, similar to our interviews, these factors reversed in importance, with the outcome being an infrequent consideration and new capabilities moti- vating purchase.13 In a sequential study, our qualitative phase directs the quantitative phase, so comparisons are interesting but secondary to our primary objectives. Doctors care about treatment outcomes, but when considering major purchases, cost, added capabilities, workflow integration, and efficiency are considered most often. Orthodontics is a business, and as such, the cost is the most critical factor for adoption across all groups. However, financial and performance consid- erations are more of a barrier than an inducement for most technologies. Effect of a new tool on office effi- ciency is a major incentive and barrier, pointing to the importance of easy onboarding and workflow integra- tion. As hypothesized, primary adoption factors include cost, added capabilities, efficiency, performance, and ease of integration. The survey sample consists of private practitioners actively working in orthodontics-only, group multispe- cialty, sole-ownership, partnership, or corporate prac- tices. The sample was biased by including feedback from orthodontists who pay membership dues to the AAO and participate in an online survey; these are more technologically savvy practitioners who are comfortable with computers and, therefore, more likely to adopt the technology. Data on the influence of tech- nologies were also subject to recall bias. Late adopters more negatively perceived the same technologies as early Journal of Orthodontics and Dentofacial Orthopedics Jacox et al 373 and middle adopters, suggesting confirmation bias; adopters tended to interpret and recall information in a way that confirmed their existing beliefs. Because the survey was lengthy, the sample was also skewed toward practitioners who had time to respond. The total number of responding dentists cannot be fully controlled and was at the low end of our anticipated range of 7%- 11%, on the basis of response rates of similar studies.14,16 The length and complexity of our survey were likely a deterrent,and the small sample size may cause us to miss meaningful data on national trends that could benefit from further investigation. Despite these limitations, understanding the technol- ogy adoption landscape is valuable to the future devel- opment and adoption of digital dental tools. By determining who is making purchasing decisions, what information and incentives form the basis of decisions, and what types of technologies orthodontists are hoping to buy, we can help forward the digital revolution in or- thodontics, as technologies prove themselves to be effective adjuncts to practitioner expertise. CONCLUSIONS The first national survey of AAO membership on technology adoption demonstrates: 1. Purchase decisions are made by practice owners af- ter consulting other dentists, company representa- tives, and conference continuing education. Published literature and staff input rarely impact adoption decisions. 2. Early adopters charge higher fees and have larger practices than middle and late adopters. 3. Primary adoption factors include cost, added capa- bilities, practice efficiency, ease of implementation, and performance. The largest barrier to adoption is cost. AUTHOR CREDIT STATEMENT Laura Anne Jacox contributed to project administra- tion, supervision, funding acquisition, conceptualiza- tion, investigation, formal analysis, visualization, original draft preparation, and manuscript review and editing; Clare Bocklage contributed to investigation, visualization, and manuscript review and editing; Teresa Edwards contributed to methodology, validation, and manuscript review and editing; Paul Mihas contributed to methodology, validation, and manuscript review and editing; Feng-Chang Lin contributed to formal analysis and manuscript review and editing; and Ching-Chang Ko contributed to supervision, funding acquisition, and manuscript review and editing. American Journal of Orthodontics and Dentofacial Orthoped ACKNOWLEDGMENTS We thank all participating orthodontists for their valuable time and willingness to participate in a lengthy online survey. We appreciate the AAO Partners in Research Program for their help and support. 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