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Solutions for Carboxylic Acid Derivatives
49 continued
HH2N O
(e)
C
HH2N O
H
C
HH2N O
H
C
N O
HH H
C
N O
HH
H H
C
N O
HH
H
H– H2OC
N
H
H
C
N
H
H
H2OC
N H
H2OH A
H
A
CCH3
O
OC
O
H3C C
O
O CCH3
O
OH
H3C
H
C
O
OH3C H
O H
H
O CCH3
O
H
OH C4H9
C
O
H3C
CCH3
O
O
+
+
(g)
+
R configuration
No bond to the chiral center 
is broken, so the 
configuration is retained.
still R
(f)
OH2N O
CH3
N O
H H
OCH3
N O
H H
OCH3
H
N O
C
O
O
NH2
Ph C
O
O
C CH3
O
PhCH2OH
C
O
NHCH3
N
H OH
C
O
OCH3
C N
O
Ph
CH3
PhCH2CHCH2NH2
COOH
O
C N
H
OH
Ph
HO Ph (i)(h)(g)(f)(e)
(d)(c)(b)(a)
50
(k)(j) (l)
O
OH
O
OH
transesterification
Na+
536