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25/04/2018 1 Henry Okigami\ Fitoterapia Saúde e Esporte 25/04/2018 2 The complex links between dietary phytochemicals and human health deciphered by metabolomics Mol. Nutr. Food Res. 2009, 53, 1303 – 1315 25/04/2018 3 Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges Seminars in Cancer Biology xxx (2016) xxx–xxx Phytochemical Therapies in Vascular Functioning: A Molecular Approach Current Vascular Pharmacology, 2017, 15, 327-338 25/04/2018 4 Phytochemical Therapies in Vascular Functioning: A Molecular Approach Current Vascular Pharmacology, 2017, 15, 327-338 Dietary Capsaicin Protects Cardiometabolic Organs from Dysfunction Nutrients 2016, 8, 174; 25/04/2018 5 The search for compounds that stimulate thermogenesis in obesity management: from pharmaceuticals to functional food ingredients obesity reviews (2011) 12, 866–883 Dietary Capsaicin Protects Cardiometabolic Organs from Dysfunction Nutrients 2016, 8, 174; 25/04/2018 6 Anti-hypertensive Herbs and their Mechanisms of Action: Part I Frontiers in Pharmacology January 2016|Volume6|Article323 Lipid-Modifying Effects of Nutraceuticals: An Evidence-Based Approach Nutrition 25/04/2018 7 Polyphenol protection and treatment of hypertension Phytomedicine Anti-hypertensive Herbs and their Mechanisms of Action: Part I Frontiers in Pharmacology January 2016|Volume6|Article323 25/04/2018 8 Anti-hypertensive Herbs and their Mechanisms of Action: Part I Frontiers in Pharmacology January 2016|Volume6|Article323 Anti-hypertensive Herbs and their Mechanisms of Action: Part I Frontiers in Pharmacology January 2016|Volume6|Article323 25/04/2018 9 Curcumin: A Pleiotropic Phytonutrient in Diabetic Complications Nutrition Crocus sativus L. (saffron) for cancer chemoprevention: A mini review Journal of Traditional and Complementary Medicine 5 (2015) 81e87 25/04/2018 10 Beneficial properties of phytochemicals on NLRP3 inflammasome-mediated gout and complication J. Agric. Food Chem., DOI: 10.1021/acs.jafc.7b05113 Mitochondrial Biogenesis in Neurodegeneration Journal of Neuroscience Research 00:00–00 (2017) 25/04/2018 11 Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities Cancer Metastasis Rev (2012) 31:323–351 Alzheimer’s Disease and Medicinal Plants: An Overview Advances in Neurobiology 12, DOI 10.1007/978-3-319-28383-8_6 25/04/2018 12 Alzheimer’s Disease and Medicinal Plants: An Overview Advances in Neurobiology 12, DOI 10.1007/978-3-319-28383-8_6 Modulation of estrogen chemical carcinogenesis by botanical supplements used for postmenopausal women’s health Drug Discovery Today: Disease Mechanisms Vol. 9, No. 1–2 2012 25/04/2018 13 Black tea improves attention and self-reported alertness Appetite 56 (2011) 235–240 Black tea improves attention and self-reported alertness Appetite 56 (2011) 235–240 25/04/2018 14 Black tea improves attention and self-reported alertness Appetite 56 (2011) 235–240 Black tea improves attention and self-reported alertness Appetite 56 (2011) 235–240 25/04/2018 15 Black tea improves attention and self-reported alertness Appetite 56 (2011) 235–240 Black tea improves attention and self-reported alertness Appetite 56 (2011) 235–240 25/04/2018 16 Fernblock (Polypodium leucotomos Extract): Molecular Mechanisms and Pleiotropic Effects in Light-Related Skin Conditions, Photoaging and Skin Cancers, a Review Int. J. Mol. Sci. 2016, 17, 1026; doi:10.3390/ijms17071026 Phytoestrogens as alternative hormone replacement therapy in menopause: What is real, what is unknown Journal of steroid Biochemistry & Molecular Biology 143(2014)61–71 25/04/2018 17 Phytochemicals Targeting Estrogen Receptors: Beneficial Rather Than Adverse Effects? Int. J. Mol. Sci. 2017, 18, 1381; doi:10.3390/ijms18071381 Phytoestrogens as alternative hormone replacement therapy in menopause: What is real, what is unknown Journal of steroid Biochemistry & Molecular Biology 143(2014)61–71 25/04/2018 18 Dietary nitrate supplementation in cardiovascular health: an ergogenic aid or exercise therapeutic? Am J Physiol Heart Circ Physiol 314: H195–H212, 2018. Regulation of mitochondrial function and energetics by reactive nitrogen oxides Free Radical Biology and Medicine 53(2012)1919–1928 25/04/2018 19 Dietary nitrate supplementation in cardiovascular health: an ergogenic aid or exercise therapeutic? Am J Physiol Heart Circ Physiol 314: H195–H212, 2018. Vascular effects of dietary nitrate (as found in green leafy vegetables and beetroot) via the nitrate-nitrite-nitric oxide pathway Br J Clin Pharmacol / 75:3 / 677–696 / 677 25/04/2018 20 Effect of Mucuna pruriens on semen profile and biochemical parameters in seminal plasma of infertile men Fertil Steril 2008;90:627–35. Mucuna pruriens improves male fertility by its action on the hypothalamus–pituitary–gonadal axis Fertil Steril 2009;92:1934–40. 25/04/2018 21 Mucuna pruriens improves male fertility by its action on the hypothalamus–pituitary–gonadal axis Fertil Steril 2009;92:1934–40. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia xx, 1–5 25/04/2018 22 Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia xx, 1–5 Clinical Assessment of a Supplement of Pycnogenol® and L‐arginine in Japanese Patients with Mild to Moderate Erectile Dysfunction Phytother. Res. (2011) 10 mg of Pycnogenol®, 115 mg of L‐arginine and 92 mg of aspartic acid 25/04/2018 23 Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males Fertil Steril 2010;94:989–96. W. somnifera root poder (5 g/day) Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial Journal of the International Society of Sports Nutrition (2015) 12:43 300 mg of ashwagandha root extract 2 x day 25/04/2018 24 Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial Journal of the International Society of Sports Nutrition (2015) 12:43 300 mg of ashwagandha root extract 2 x day Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial Journal of the International Society of Sports Nutrition (2015) 12:43 300 mg of ashwagandha root extract 2 x day 25/04/2018 25 Supplementation with a Polyphenol-Rich Extract, PerfLoad®, Improves Physical Performance during High-Intensity Exercise: A Randomized, Double Blind, Crossover Trial Nutrients 2017, 9, 421; doi:10.3390/nu9040421 Vitis vinifera L. Punica granatum L.). tCamellia sinensis L. Kuntze Herbs in exercise and sports Journal of Physiological Anthropology 2012, 31:4 25/04/2018 26 Herbs in exercise and sports Journal of Physiological Anthropology 2012, 31:4 Herbs in exercise and sports Journal of Physiological Anthropology 2012, 31:4 25/04/2018 27 Herbs in exercise and sports Journal of Physiological Anthropology 2012, 31:4 Herbs in exercise and sports Journal of Physiological Anthropology 2012, 31:4 25/04/2018 28 Herbs in exercise and sports Journal of Physiological Anthropology 2012, 31:4 Fitoterapia • Potencial enorme. • Interação com nutrientes para sinergia. • Alimentos podemser fitoterápicos. • Prevenção. • Tratamento. • Esporte. 25/04/2018 29 Obrigado www.arvoredoconhecimento.com.br/henryokigami 25/04/2018 30 Henry Okigami\