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Front Cover Crash Course: Cardiology Copyright Series editor foreword Prefaces Authors Faculty Advisor Contents Chapter 1: History Aim of history taking Presenting complaint Chest pain Dyspnoea Syncope Palpitations Ankle swelling Systems review Respiratory system Cough Sputum Haemoptysis Wheeze Gastrointestinal system Appetite Weight loss or gain Nausea and vomiting Indigestion Diarrhoea and constipation Central nervous system Headache Weakness, sensory loss, visual or speech disturbance Skin and joints Rashes Joint pain Genitourinary system Proteinuria Haematuria Frequency, hesitancy, nocturia and terminal dribbling Impotence and failure of ejaculation Past medical history Family history Social history Drug history Allergies Presenting history findings Chapter 2: Examination How to begin the examination Observation Examination of the hands Examination of the pulse Taking the blood pressure Examination of the face Examination of the jugular venous pressure Kussmaul sign Examination of the praecordium Inspection Palpation Auscultation Finishing off the examination Presenting your findings Chapter 3: How to write a clerking Documentation of the history Systems review Risk calculation Documentation of the examination findings At the end of the clerking Further reading Sample medical clerking Chapter 4: Common investigations Electrocardiography Lead placement Limb leads Chest leads 12-lead electrocardiogram Leads I, II and III AVR, AVL and AVF Chest leads QRS axis Paper speed P wave QRS complex ST segment T wave QT interval Q waves U wave Reporting an electrocardiogram Exercise electrocardiography Indications for exercise testing Methods of exercise Patient preparation Variables measured 12-lead electrocardiogram Blood pressure Heart rate response Test end-points Positive exercise test Contraindications to exercise testing Echocardiography M mode echocardiography Two-dimensional echocardiography Doppler echocardiography Other echocardiography modalities Transoesophageal echocardiography Stress echocardiography Myocardial perfusion imaging Methods of stressing the heart Multigated acquisition scanning Cardiac magnetic resonance Positron emission tomography Cardiac catheterization Technique Left heart catheterization and coronary angiography Indications Patient preparation Left ventriculography Coronary angiography Complications of coronary angiography Cardiac computed tomography Chapter 5: Chest pain Differential diagnosis of chest pain History to focus on the differential diagnosis of chest pain Presenting complaint Past medical history Drug history, family history and social history Examination of patients who have chest pain Inspection Cardiovascular system Respiratory system Gastrointestinal system Investigation of patients who have chest pain Blood tests Electrocardiography Chest radiography Echocardiography Computed tomography and magnetic resonance imaging Ventilation/perfusion (V/Q) scan Angiography, myocardial perfusion imaging or stress echocardiography New onset central chest pain at rest in an ill patient Dissection of the thoracic aorta Mediastinitis Pulmonary embolus Chapter 6: Dyspnoea Differential diagnosis of dyspnoea History to focus on the differential diagnosis of dyspnoea Examination of dyspnoeic patients Inspection Cardiovascular system Respiratory system Gastrointestinal system Investigation of dyspnoeic patients Blood tests Electrocardiography Chest radiography Echocardiography Computed tomography Pulmonary function tests Dyspnoea at rest of recent onset in an ill patient Pneumothorax Acute asthma Acute left ventricular failure Pulmonary embolus Pneumonia Chapter 7: Syncope Differential diagnosis of syncope History to focus on the differential diagnosis of syncope Past medical history Drug history Family history Social history Examination of patients who present with syncope Cardiovascular system Neurological system Fingerprick test for blood glucose Investigation of patients who present with syncope Blood tests Electrocardiography Holter monitor Tilt test Chest radiography Echocardiography Electrophysiological study of the heart Electroencephalography Syncope of recent onset in an ill patient Differentiating features of syncope Cardiac causes Aortic stenosis Tachyarrhythmias Bradyarrhythmias Cardiomyopathies Prolonged QT interval Brugada syndrome Circulatory causes Hypovolaemia Septic shock Classic postural hypotension Obstruction of pulmonary arteries Cerebrovascular causes Stroke and transient cerebral ischaemia Vertebrobasilar syndrome Other neurological causes Metabolic causes Chapter 8: Palpitations Differential diagnosis of palpitation Rapid palpitations Slow palpitations Disorders causing increased stroke volume History to focus on the differential diagnosis of palpitation Nature of the palpitation Severity of palpitation Likely underlying causes of palpitation Examination of patients who have palpitation General observation Cardiovascular system Pulse Blood pressure Jugular venous pressure Apex beat Heart sounds Respiratory system Gastrointestinal system Limbs Investigation of patients who have palpitation Biochemical tests Electrocardiography 12-lead electrocardiography 24-h electrocardiography Exercise electrocardiography Vagotonic manoeuvres Adenosine administration Echocardiography Electrophysiological study Other investigations Chapter 9: Peripheral oedema Differential diagnosis of oedema History to focus on the differential diagnosis of peripheral oedema Past medical history Drug history Social history Examination of patients who have oedema Cardiovascular system Respiratory system Gastrointestinal system Renal system Examination of the oedema Investigation of patients who have oedema Blood tests Urine tests Arterial blood gases Electrocardiography Chest radiography Echocardiography Ultrasound Important aspects Salt and water retention Increase in extracellular water and intravascular blood volume Hypertension treated with calcium antagonists Chapter 10: Heart murmur Differential diagnosis of a heart murmur History to focus on the differential diagnosis of a heart murmur Presenting complaint Past medical history Social history Examination of patients who have a heart murmur General observation Hands Cardiovascular system Pulse Blood pressure Jugular venous pressure Praecordium Peripheral vascular system Peripheral oedema Respiratory system Gastrointestinal system Investigation of patients who have a heart murmur Blood tests Chest radiography Electrocardiography Echocardiography Transthoracic echocardiography Transoesophageal echocardiography Cardiac catheterization Chapter 11: High blood pressure Differential diagnosis History to focus on the differential diagnosis of high blood pressure Presenting complaint Past medical history Drug history Family history Social history Examination of patients who have high blood pressure Blood pressure Cardiovascular examination Respiratory system Gastrointestinal system Limbs Eyes Other findings on examination Investigation of patients who have high blood pressure Ambulatory blood pressure monitoring Home blood pressure monitoring Blood tests Urinalysis Electrocardiography Chest radiography Echocardiography Investigations to exclude secondary hypertension Chapter 12: Fever associated with a cardiac symptom or sign Differential diagnosis Rare conditions History to focus on the differential diagnosis of fever Presenting complaint Past medical history Drug history Social history Examination of patients who have a fever associated with a cardiac symptom or sign Temperature Hands Facies Cardiovascular system Pulse Blood pressure Jugular venous pressure Praecordium Respiratory system Gastrointestinal system Skin Investigation of patients who have a fever associated with a cardiac symptom or sign Blood tests Blood cultures Full blood count Other blood tests Urinalysis Electrocardiography Chest radiography Transthoracic echocardiography Transoesophageal echocardiography Pericardiocentesis Chapter 13: Angina pectoris Definition of angina pectoris Pathophysiology of angina pectoris Risk factors for coronary artery disease Clinical features of angina pectoris Symptoms Signs Investigation of angina pectoris Coronary angiography Management of angina pectoris Management of the risk factors Treatment of the angina Drug therapy Aspirin β-Blockers Calcium channel antagonists Nitrates Potassium channel openers New anti-anginals Management plan for angina pectoris Revascularization Percutaneous intervention Advantages of PCI Disadvantages of PCI Complications of PCI Coronary artery bypass grafting Complications of coronary artery bypass grafting Minimally invasive coronary artery bypass grafting Unstable angina Management Further reading Chapter 14: Acute myocardial infarction Definition of acute myocardial infarction Clinical features of acute myocardial infarction History Presenting complaint Past medical history Examination Cardiovascular system Investigation of acute myocardial infarction Blood tests Indicators of myocardial damage Troponin T and troponin I Creatine kinase Renal function and electrolytes Blood glucose Full blood count Serum cholesterol Electrocardiography ECG changes in non-ST-elevation myocardial infarction Chest radiography Echocardiography Management of acute myocardial infarction Treatment Indications for primary PCI Contraindications Other agents used for acute myocardial infarction Aspirin Other antiplatelet agents Diamorphine β-Blockers (β-adrenoceptor antagonists) Oxygen Non-acute management Cardiac rehabilitation Summary of management of ischaemic chest pain Heart block after myocardial infarction Management of postmyocardial infarction heart block Cardiogenic shock after myocardial infarction Chapter 15: Supraventricular tachyarrhythmias Sinus tachycardia Causes Premature atrial complexes Nodal and junctional ectopics Atrial tachycardia Causes Investigation and diagnosis Management Atrioventricular junctional tachycardia Clinical features Management Atrioventricular nodal re-entry tachycardia Clinical features Diagnosis Management Wolff-Parkinson-White syndrome Characteristics of the bundle of Kent Tachycardias associated with Wolff-Parkinson-White syndrome Clinical features Management Drug therapy Ablation therapy Atrial flutter Investigations and diagnosis Management Atrial fibrillation Causes Investigations and diagnosis Management Anticoagulation and atrial fibrillation Anticoagulation and cardioversion of AF Investigation of patients who have supraventricular tachyarrhythmias Blood tests Electrocardiography 24- or 48-h electrocardiography Chest radiography Echocardiography Electrophysiological studies Atrioventricular nodal blocking manoeuvres Carotid sinus massage Adenosine administration Actions of adenosine Drugs used to treat tachyarrhythmias Further reading Chapter 16: Ventricular arrhythmias Ventricular ectopic beats Clinical features Management Definition of ventricular tachyarrhythmias Ventricular tachycardia Clinical features Diagnosis Management Electrophysiological studies Torsades de pointes Clinical features Management Ventricular fibrillation Clinical features Management Drugs used to treat ventricular tachycardia and fibrillation Non-pharmacological treatments of ventricular tachyarrhythmias Radiofrequency ablation Implantable cardioverter defibrillators Further reading Chapter 17: Cardiac arrest and resuscitation Basic life support Principle of chest compressions Recovery position Management of upper airway obstruction by foreign material Advanced life support Points to note about advanced life support Protocol Airway ventilation and protection Placing the defibrillator pads The ventricular tachycardia/fibrillation arm of the advanced life support algorithm The non-VT/VF arm of the ALS algorithm In-hospital cardiac arrest Further reading Chapter 18: Bradyarrhythmias Definition of bradyarrhythmias Sinus bradycardia Sinus node disease Tachy-brady syndrome (sick sinus syndrome) Management Atrioventricular block First-degree atrioventricular block Second-degree atrioventricular block Mobitz type I heart block - Wenckebach phenomenon Mobitz type II heart block 2:1 or 3:1 heart block Third-degree or complete heart block Bundle branch block Left bundle branch block Right bundle branch block Investigation of bradyarrhythmias Electrocardiography Blood tests Chest radiography Echocardiography Pacemakers Indications for a permanent pacemaker Indications for temporary pacing Pacemaker insertion Complications of pacemaker insertion Types of pacemaker Pacemaker syndrome Further reading Chapter 19: Heart failure Definition of heart failure Pathophysiology of heart failure Normal myocardial response to work The failing heart's response to work Salt and water retention in heart failure Other neurohumoral factors Natriuretic peptides Cytokines Endothelin Galectin-3 Causes of cardiac failure Precipitants Clinical features of heart failure Forward effects Backward effects Symptoms Examination of patients who have heart failure Cardiovascular system Respiratory system Gastrointestinal system Investigation of heart failure Blood tests Electrolytes and renal function Full blood count Liver function tests Brain natriuretic peptide Arterial blood gases Electrocardiography Chest radiography Echocardiography Cardiac catheterization Management of heart failure Management of acute left ventricular failure Management of acute right ventricular failure Management of chronic heart failure Angiotensin-converting enzyme inhibitors Clinical use of angiotensin-converting enzyme inhibitors Angiotensin II receptor blockers β-Blockers Diuretics Aldosterone antagonists Nitrates Digoxin Pharmacokinetics Side effects Hydralazine Cardiac resynchronization therapy Further reading Chapter 20: Cardiomyopathy Definition of cardiomyopathy Dilated cardiomyopathy Clinical features Investigation Chest radiography Electrocardiography Echocardiography Cardiac catheterization Magnetic resonance imaging Blood tests Management Hypertrophic cardiomyopathy Clinical features Diagnosis and investigations Electrocardiography Continuous ambulatory electrocardiography Echocardiography Exercise testing Prognosis Management Device therapy Percutaneous treatment (alcohol septal ablation) Surgery Restrictive cardiomyopathy Clinical features Management Arrhythmogenic right-ventricular cardiomyopathy Takotsubo cardiomyopathy Further reading Chapter 21: Pericarditis and pericardial effusion Acute pericarditis Clinical features History Examination Investigation Blood tests Electrocardiography Chest radiography Echocardiography Management Dressler syndrome Constrictive pericarditis Clinical features Examination Investigation Management Pericardial effusion Causes Clinical features History Examination Possible mechanisms for pulsus paradoxus Investigation Electrocardiography Management Further reading Chapter 22: Valve disease Rheumatic fever Causes Clinical features Investigations Management Mitral stenosis Causes Clinical features Examination Investigations Electrocardiography Chest radiography Echocardiography Cardiac catheterization Management Medical management Mitral valvuloplasty Surgical management Open mitral valvotomy Closed mitral valvotomy Mitral valve replacement Mitral regurgitation Pathophysiology Clinical features Examination Mitral valve prolapse Investigations Electrocardiography Chest radiography Echocardiography Cardiac catheterization Management Medical management Surgical management Mitral valve repair Mitral valve replacement Aortic stenosis Pathophysiology Clinical features Examination Investigations Electrocardiography Chest radiography Echocardiography Cardiac catheterization Management Medical management Percutaneous and trans-apical valves Surgical management Aortic regurgitation Pathophysiology Clinical features Examination Investigations Electrocardiography Chest radiography Echocardiography Cardiac catheterization Management Medical management Surgical management Assessing the severity of a valve lesion Tricuspid regurgitation Causes Ebstein anomaly Clinical features Management Other valve lesions Prosthetic heart valves Further reading Chapter 23: Infective endocarditis Definition of infective endocarditis Epidemiology of infective endocarditis Pathophysiology of infective endocarditis Clinical features of infective endocarditis History Examination Investigation of a patient who has infective endocarditis Blood tests Blood cultures Full blood count Erythrocyte sedimentation rate and C-reactive protein Renal function Liver function tests Electrocardiography Urinanalysis Chest radiography Echocardiography Management of infective endocarditis Antibiotic therapy Choice of antibiotic regimen Duration of antibiotic therapy Monitoring antibiotic therapy Complications of infective endocarditis Monitoring of patients who have infective endocarditis Further reading Chapter 24: Hypertension Definition of hypertension Causes of hypertension Clinical features of hypertension History Examination Investigation of a patient who has hypertension Investigation of secondary hypertension Management of hypertension Importance of treating hypertension Non-pharmacological management Pharmacological management Recommended treatment of hypertension Follow-up of patients who have hypertension Cardiovascular risk Phaeochromocytoma Clinical features Investigations Management Further reading Chapter 25: Congenital heart disease Definition of congenital heart disease Causes of congenital heart disease Complications of congenital heart disease Atrial septal defect Clinical features History Examination Investigation Electrocardiography Chest radiography Echocardiography Cardiac catheterization Magnetic resonance imaging Management Patent foramen ovale Ventricular septal defect Clinical features History Examination Investigation Chest radiography Echocardiography Magnetic resonance imaging Management Patent ductus arteriosus Clinical features History Examination Management Coarctation of the aorta Clinical features History Examination Investigation Electrocardiography Chest radiography Echocardiography Cardiac catheterization Magnetic resonance imaging Management Other lesions in congenital heart disease Notes on pulmonary hypertension and Eisenmenger syndrome Pulmonary hypertension Eisenmenger syndrome Further reading Self-Assessment Best of fives (BOFs) Extended-matching questions (EMQs) BOF answers EMQ answers Glossary Index
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