Aula 06 - NP2

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MICOSES
Dr. José S. Soares
Aula 07
Dr. Zezinho
MICOSES
Superficiais (cabelo, unhas, córnea)
Cutâneas
Subcutânea
Sistêmica (endêmica)
Oportunistas
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Classificação das micoses e seus agentes etiológicos
Micoses superficiais
Piedra negra (Piedraia hortae)
Piedra branca (Trichosporon beigeli)
Tinha nigra (Phaeoannelomyces wernickii)
Pitiriase versicolor (Malassezia furfur)
Onicomicose (Cândida spp, Aspergillus spp., Fusarium spp.)
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Classificação das micoses e seus agentes etiológicos
Micoses cutâneas
Dermatomicose
Microsporum spp.
Trichophyton spp.
Epidermophyton floccosum
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Classificação das micoses e seus agentes etiológicos
Micoses subcutâneas
Maduromicose –micetoma-
Acremonium spp., Exophiala jeanselmei, Pseudallescheria boydii, Nocardia spp.
Cromoblastomicose
Cladosporium carionii, Fonsecae spp., Phialophora spp.
Feohifomicose
Alternaria spp., Cladosporium spp., Xylohypha emmonsii, Exophiala spp., Phialophora spp., Wangiella dermatidis
Esporotricose
Sporothrix schenckii
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Classificação das micoses e seus agentes etiológicos
Micoses profundas ou sistêmicas
Blastomicose
Blastomyces dermatidis
Coccidiodomicose
Coccidiodis immitis
Criptococose
Criptococcus neoformans. 
Histoplasmose
Histoplasma capsulatum
Paracoccidiodomicose
Paracoccidiodes brasiliensis
Esporotricose (inusual)
Sporothrix schenckii
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Micoses oportunistas
Aspergilose (Aspergillus fumigatus, A. flavus, A. niger, A. terreus)
Candidiase (Cândida albicans, C. spp.)
Geotricose (Geotrichum candidum)
Feohifomicose (Alternaria spp., Curvularia spp., Exophiala spp., Wangiella spp.)
Hialohifomicose (Acremonium spp., Fusarium spp., Paecilomyces spp., Penicillium spp., Scedosporium spp.)
zigomicose (Rhizopus spp., Mucor spp., Cunninghamella spp.)
Classificação das micoses e seus agentes etiológicos
7
DIAGNÓSTICO LABORATORIAL DAS MICOSES
•     Exame microscópico direto
	Gram, hidróxido potássio (KOH), branco cálcio flúor, tinta Índia
•     Cultura 
	Agar dextrosa Sabouraud 
	Agar Micobiotica
•     Sorologia 
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Termos úteis usados no exame dos fungos
9
Como descrever os fungos…
Levedura
Blastoconidias
pseudo-hifas
Tubo germinativo
Hifas
Septadas
Cenocítica
ramificada
Micélio
Vegetativo
Aéreo (reprodutivo)
Células conidiogenas
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Tipos de reprodução dos fungos
Esporulação vegetativa
Esporulação aérea
Esporulação sexual
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Anthropophilic
Zoophilic
Geophilic
Epidermophyton floccosum
Microsporum audouinii
Microsporum ferrugineum
Trichophyton concentricum
Trichophyton kanei
Trichophyton megninii
Trichophyton mentagrophytes
Trichophyton raubitschekii
Trichophyton rubrum
Trichophyton schoenleinii
Trichophyton soudanense
Trichophyton tonsurans
Trichophyton violaceum
Trichophyton yaoundei
Microsporum canis (cats, dogs, etc.)
Microsporum equinum (horses)
Microsporum nanum (pigs)
Microsporum persicolor(rodents)
Trichophyton equinum (horses)
Trichophyton mentagrophytes(granular)
(rodents, rabbits, hedgehogs, etc.)
Trichophyton simii (monkeys)
Trichophyton verrucosum (cattle)
Microsporumgypseum
Trichophytonajelloi
Trichophytonterrestre
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Clinical
manifestation
Organism
Geographical distribution
Tineabarbae
(beard)
Microsporum canis
North America, some areas of Europe
Trichophyton megninii
Spain, Portugal, Sardinia
Trichophyton mentagrophytes
Worldwide
Trichophyton rubrum
Worldwide
Trichophyton verrucosum
Worldwide
Trichophyton violaceum
North Africa, East Africa, Middle East
.
Tinea capitis
(scalp and hair)
Microsporum audouinii
Eastern Europe, rare in North America
Microsporum canis
North America, some areas of Europe
Microsporum ferrugineum
Africa, India, China, Japan
Microsporum gypseum
Worldwide
Microsporum nanum
Worldwide
Microsporum persicolor
Worldwide
Trichophyton megninii
Spain, Portugal, Sardinia
Trichophyton mentagrophytes
Worldwide
Trichophyton schoenleinii
Europe, Asia, Africa
Trichophyton soudanense
Africa
Trichophyton tonsurans
Worldwide
Trichophyton verrucosum
Worldwide
Trichophyton violaceum
North Africa, East Africa, Middle East
13
.
Tineacorporis
(glabrous skin)
Epidermophyton floccosum
Worldwide
Microsporum audouinii
Eastern Europe, rare in North America
Microsporum canis
North America, some areas of Europe
Microsporum gypseum
Worldwide
Microsporum nanum
Worldwide
Microsporum persicolor
Worldwide
Trichophyton equinum
Worldwide
Trichophyton mentagrophytes
Worldwide
Trichophyton raubitschekii
Asia, Africa, Middle East, North America
Trichophyton rubrum
Worldwide
Trichophyton schoenleinii
Europe, Asia, Africa
Trichophyton tonsurans
Worldwide
Trichophyton verrucosum
Worldwide
Trichophyton violaceum
North Africa, East Africa, Middle East
.
Tinea cruris
(groin)
Epidermophyton floccosum
Worldwide
Microsporum nanum
Worldwide
Trichophyton mentagrophytes
Worldwide
Trichophyton raubitschekii
Asia, Africa, Middle East, North America
Trichophyton rubrum
Worldwide
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.
Tinea manuum
(hand)
Epidermophyton floccosum
Worldwide
Microsporum canis
North America, some areas of Europe
Microsporum gypseum
Worldwide
Trichophyton mentagrophytes
Worldwide
Trichophyton rubrum
Worldwide
Trichophyton verrucosum
Worldwide
.
Tinea pedis
(feet)
Epidermophyton floccosum
Worldwide
Microsporum persicolor
Worldwide
Trichophyton mentagrophytes
Worldwide
Trichophyton raubitschekii
Asia, Africa, Middle East, North America
Trichophyton rubrum
Worldwide
Trichophyton violaceum
North Africa, East Africa, Middle East
15
.
Tinea unguium
(nails)
Epidermophyton floccosum
Worldwide
Trichophyton mentagrophytes
Worldwide
Trichophyton rubrum
Worldwide
Trichophyton tonsurans
Worldwide
Trichophyton violaceum
North Africa, East Africa, Middle East
.
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