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What is the cause of sickle cell anemia? Sickle cell anemia is caused by a substitution of a single nucleotide that changes the codon for the sixt...

What is the cause of sickle cell anemia?

Sickle cell anemia is caused by a substitution of a single nucleotide that changes the codon for the sixth amino acid of β-globin from glutamic acid to valine.
Sickle cell anemia is caused by a deletion of a single nucleotide that changes the codon for the sixth amino acid of β-globin from glutamic acid to valine.
Sickle cell anemia is caused by an insertion of a single nucleotide that changes the codon for the sixth amino acid of β-globin from glutamic acid to valine.
Sickle cell anemia is caused by a substitution of a single nucleotide that changes the codon for the sixth amino acid of α-globin from glutamic acid to valine.

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A causa da anemia falciforme é a substituição de um único nucleotídeo que altera o códon para o sexto aminoácido da β-globina de ácido glutâmico para valina. Portanto, a alternativa correta é: "Sickle cell anemia is caused by a substitution of a single nucleotide that changes the codon for the sixth amino acid of β-globin from glutamic acid to valine."

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