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Assuming that the non-disjunction event occurs during meiosis, analyze the following statements: I- Non-disjunction is the failure of homologous c...

Assuming that the non-disjunction event occurs during meiosis, analyze the following statements:
I- Non-disjunction is the failure of homologous chromosomes to separate during meiosis I or the failure of sister chromatids to separate during meiosis II.
II- Non-disjunction can occur in both meiosis I and meiosis II.
III- Non-disjunction can lead to the formation of gametes with an abnormal number of chromosomes.
IV- Non-disjunction can lead to genetic disorders such as Down syndrome.
V- Non-disjunction events occur during the S phase of the cell cycle, that is, during chromosome duplication.
Choose the correct alternative:

I- Non-disjunction is the failure of homologous chromosomes to separate during meiosis I or the failure of sister chromatids to separate during meiosis II.
II- Non-disjunction can occur in both meiosis I and meiosis II.
III- Non-disjunction can lead to the formation of gametes with an abnormal number of chromosomes.
IV- Non-disjunction can lead to genetic disorders such as Down syndrome.
V- Non-disjunction events occur during the S phase of the cell cycle, that is, during chromosome duplication.
a. I, III and V are correct.
b. I, IV and V are correct.
c. II and IV are correct.
d. II, III and IV are correct.
e. III, IV and V are correct.

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Questionário 1
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Biologia, Histologia e Embriologia Universidade PaulistaUniversidade Paulista

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A alternativa correta é a letra B) I, IV e V estão corretas. Explicação: I- Non-disjunction é a falha na separação dos cromossomos homólogos durante a meiose I ou a falha na separação das cromátides irmãs durante a meiose II. II- Non-disjunction pode ocorrer tanto na meiose I quanto na meiose II. III- Non-disjunction pode levar à formação de gametas com número anormal de cromossomos. IV- Non-disjunction pode levar a distúrbios genéticos, como a Síndrome de Down. V- Non-disjunction ocorre durante a meiose, não durante a fase S do ciclo celular. Portanto, apenas as afirmações I, IV e V estão corretas.

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