Schistosoma mansoni, popularly known as "schistosomiasis" or "blood fluke," and Fasciola hepatica, popularly known as "liver fluke," are two different parasites that infect humans and animals. Regarding their habitat, Schistosoma mansoni is commonly found in freshwater bodies such as lakes, rivers, and ponds, mainly in tropical and subtropical regions. On the other hand, Fasciola hepatica is found in the liver and bile ducts of various mammals, including humans, sheep, and cattle. Both Schistosoma mansoni and Fasciola hepatica have a heteroxenic cycle, which means they require multiple hosts to complete their life cycle. In the case of Schistosoma mansoni, the intermediate host is a specific type of freshwater snail called Biomphalaria, while humans are the definitive host. For Fasciola hepatica, the intermediate host is a specific type of freshwater snail called Galba truncatula, and the definitive hosts are various mammals, including humans. The biological cycle differences between Schistosoma mansoni and Fasciola hepatica lie in their mode of transmission and the organs they infect. Schistosoma mansoni is transmitted when humans come into contact with contaminated freshwater, where the parasite's larvae (cercariae) penetrate the skin. The adult worms then reside in the blood vessels surrounding the intestines, causing schistosomiasis. On the other hand, Fasciola hepatica is transmitted when humans consume water or food contaminated with the parasite's metacercariae. The adult worms then migrate to the liver, causing fascioliasis. The pathogenesis of Schistosoma mansoni and Fasciola hepatica involves the damage caused by the parasites to the host's organs. In the case of Schistosoma mansoni, the adult worms lay eggs that can become trapped in the liver, intestines, or other organs, leading to inflammation, fibrosis, and various complications. Fasciola hepatica, on the other hand, causes damage to the liver and bile ducts, leading to inflammation, necrosis, and potential obstruction of the bile ducts. It's important to note that these are complex topics, and the information provided here is a simplified overview. For a more in-depth understanding, I recommend consulting reliable sources or textbooks on parasitology.
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