What are the clinical manifestations of schizophrenia? Genetic factors, biochemical factors, induced by substances, epilepsy, neoplasms, cerebrovas...

What are the clinical manifestations of schizophrenia?
Genetic factors, biochemical factors, induced by substances, epilepsy, neoplasms, cerebrovascular disease or trauma, and other conditions.
Excess of dopaminergic activity, excess of serotonin, norepinephrine related to anhedonia, loss of GABAergic inhibitory neurons could lead to hyperactivity of dopaminergic neurons, neuropeptides, glutamate, and the hypothesis proposed about glutamate includes hyperactivity, hypoactivity, and neurotoxicity induced by it.
Delusions of persecution, delusions of grandeur, hallucinations, hostility, verbal and physical self or hetero-aggressiveness.
Disorganization of thought, inappropriate laughter, inappropriate affect, and mannerisms.